ChemicalBook > Product Catalog >API >Anesthetic Agents >Local anesthetics >Ropivacaine hydrochloride
Ropivacaine hydrochloride
- CAS No.
- 132112-35-7
- Chemical Name:
- Ropivacaine hydrochloride
- Synonyms
- ROPIVACAINE HCL;ROPIVACAINE HYDROCHLORIDE MONOHYDRATE;Ropivacaine hydrochloride hydrate;LEA-103;LEA-103 HCl;Ropivacaine HCI;S-ROPIVACAINE HCL;Ropivacaine HCl.H2O;Ropivacaine HCl (mono);Ropivacaine HCl hydrate
- CBNumber:
- CB0369811
- Molecular Formula:
- C17H26N2O.ClH.H2O
- Molecular Weight:
- 328.88
- MOL File:
- 132112-35-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/11/25 7:49:43
| Melting point | 267-269°C |
|---|---|
| alpha | D20 -7.28° (c = 2 in water) |
| storage temp. | 2-8°C |
| solubility | H2O: soluble5mg/mL, clear |
| form | powder |
| color | white to off-white |
| optical activity | [α]/D -9 to -12, c = 1 in methanol |
| InChIKey | VSHFRHVKMYGBJL-CKUXDGONSA-N |
| CAS DataBase Reference | 132112-35-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H318 |
| Precautionary statements | P280-P305+P351+P338 |
| Hazard Codes | T,Xi |
| Risk Statements | 26/27/28-41 |
| Safety Statements | 22-36/37/39-45-39-26 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | 3 |
| HS Code | 2933399090 |
Ropivacaine hydrochloride price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | R0283 | Ropivacaine hydrochloride monohydrate ≥98% (HPLC) | 132112-35-7 | 10MG | ₹8540.93 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | R0283 | Ropivacaine hydrochloride monohydrate ≥98% (HPLC) | 132112-35-7 | 50MG | ₹33860.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR2303 | Ropivacaine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material | 132112-35-7 | 500MG | ₹21595.88 | 2022-06-14 | Buy |
Ropivacaine hydrochloride Chemical Properties,Uses,Production
Description
(–)-Ropivacaine is a potent and reversible blocker of sodium channels in nerve fibers. In vivo, (–)-ropivacaine induces complete impairment of proprioception, motor function, and nociception in the hindleg of rats when 100 μL of an 8 mM solution is injected percutaneously into the sciatic nerve. (–)-Ropivacaine depresses myocardial contractile force in isolated rat hearts less potently than (±)-ropivacaine, as well as (–)- and (±)-bupivacaine . Formulations containing (–)-ropivacaine have been used as local anesthetics during surgery and childbirth.
Chemical Properties
White Solid
Uses
Ropivacaine hydrochloride monohydrate has been used as an analyte in tandem mass spectrometry and as an amide-based local anaesthetic to test its effect on breast cancer cell methylation.
Definition
ChEBI: The monohydrate form of (S)-ropivacaine hydrochloride.
General Description
Ropivacaine has lidocaine-related structure with tertiary amine side chains.?It is a pure S(-)enantiomer with a propyl group on the piperidine nitrogen atom.
Ropivacaine hydrochloride Preparation Products And Raw materials
Global( 397)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| NB Healthcare Pvt Ltd | +91 7227055467 | Gujarat, India | 37 | 58 | Inquiry |
| Gonane Pharma | +91-9819380043 +91-9819380043 | NaviMumbai, India | 192 | 58 | Inquiry |
| Dishman Carbogen Amcis Ltd (Dishman Group) | +91-2717420100 +91-8154017093 | Gujarat, India | 90 | 58 | Inquiry |
| Mahendra Chemicals | +91-8511204451 +91-9824019625 | Gujarat, India | 7 | 58 | Inquiry |
| Apothecon Pharmaceuticals Pvt Ltd | +91-2662244212 +91-9099007601 | Gujarat, India | 28 | 58 | Inquiry |
| Rivashaa Agrotech Biopharma Pvt. Ltd. | +91-26463395 +91-7926462688 | Gujarat, India | 1615 | 58 | Inquiry |
| Asence Pharma Pvt Ltd | +91-265228317 +91-265228317 | Gujarat, India | 16 | 58 | Inquiry |
| MAC CHEM PRODUCTS INDIA PVT LTD | +91 22 4093 9000 / 01 | New Delhi, India | 13 | 58 | Inquiry |
| PIONEER AGRO INDUSTRIES | +91 186 2345352, 53, 54 | New Delhi, India | 1 | 58 | Inquiry |
| MAC CHEM PRODUCTS (INDIA) PVT. LTD. | +91 22 4093 9000 | New Delhi, India | 39 | 58 | Inquiry |
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IP/USP/BP/EP
132112-35-7
13112-35-7
CAS NO.98717-15
132115-35-7
C17H26N2OxHCL
C17H26N2OHCl
C17H26N2OHCLH2O
C17H28N2O2HCl
C17H26N2O2HClH2O
C17H26N2OClHH2O
Inhibitors
Chiral Reagents
Intermediates & Fine Chemicals
Pharmaceuticals
API
132112-35-7