ChemicalBook > Product Catalog >API >Anesthetic Agents >Local anesthetics >Propitocaine hydrochloride
Propitocaine hydrochloride
- CAS No.
- 1786-81-8
- Chemical Name:
- Propitocaine hydrochloride
- Synonyms
- xylonest;Prilocaine HC;PRILOCAINE HCL;Citanest Plain;Prilocaine HCI;Ropitocaine Hcl;Propitocaine HCL;l-67hydrochloride;prilocainechloride;citanesthydrochloride
- CBNumber:
- CB2139212
- Molecular Formula:
- C13H21ClN2O
- Molecular Weight:
- 256.77
- MOL File:
- 1786-81-8.mol
- Modify Date:
- 2024/8/21 22:41:43
| Melting point | 168-170°C |
|---|---|
| storage temp. | 2-8°C |
| solubility | Freely soluble in water and in ethanol (96 per cent), very slightly soluble in acetone |
| color | White to Off-White |
| Merck | 14,7743 |
| InChI | InChI=1S/C13H20N2O.ClH/c1-4-9-14-11(3)13(16)15-12-8-6-5-7-10(12)2;/h5-8,11,14H,4,9H2,1-3H3,(H,15,16);1H |
| InChIKey | BJPJNTKRKALCPP-UHFFFAOYSA-N |
| SMILES | C1(=CC=CC=C1C)NC(=O)C(C)NCCC.Cl |
| CAS DataBase Reference | 1786-81-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319-H312-H302-H315 | |||||||||
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P280-P302+P352-P312-P322-P363-P501 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UG5775000 | |||||||||
| HS Code | 29242990 | |||||||||
| Toxicity | man,LDLo,parenteral,12343ug/kg/1H (12.343mg/kg),BLOOD: HEMORRHAGE,Journal of Analytical Toxicology. Vol. 10, Pg. 75, 1986. | |||||||||
| NFPA 704 |
|
Propitocaine hydrochloride price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | P9547 | Prilocaine hydrochloride ≥98% (TLC) | 1786-81-8 | 1G | ₹7425.95 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR3106 | Prilocaine Hydrochloride pharmaceutical secondary standard, certified reference material | 1786-81-8 | 500MG | ₹16724.63 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P9547 | Prilocaine hydrochloride ≥98% (TLC) | 1786-81-8 | 5G | ₹24410.38 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P9547 | Prilocaine hydrochloride ≥98% (TLC) | 1786-81-8 | 10G | ₹40810.25 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P3347 | Prilocaine hydrochloride meets USP testing specifications | 1786-81-8 | 1G | ₹6072.83 | 2022-06-14 | Buy |
Propitocaine hydrochloride Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
Propitocaine hydrochloride is a local anesthetic of the amino amide type,it is often used in dentistry. Prilocaine is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/pril ocaine or EMLA), for treatment of conditions like paresthesia.
Definition
ChEBI: The monohydrochloride salt of prilocaine.
Biological Functions
Prilocaine hydrochloride (Citanest) is an amide anesthetic whose onset of action is slightly longer than that of lidocaine; its duration of action is comparable. Prilocaine is 40% less toxic acutely than lidocaine, making it especially suitable for regional anesthetic techniques. It is metabolized by the liver to orthotoluidine, which when it accumulates, can cause conversion of hemoglobin (HB+++ to methemoglobin (HB+++. Oxygen transport is impaired in the presence of methemoglobinemia. Treatment involves the use of reducing agents, such as methylene blue, given intravenously, to reconvert methemoglobin to hemoglobin.
Contact allergens
Prilocaine in a local anesthetic of the amide group. It can induce allergic contact dermatitis, particularly from EMLA? cream.
Side effects
Common adverse reactions include bradycardia, hypotension, urticaria, edema, anaphylactoid reactions, lightheadedness, nervousness, euphoria, confusion, dizziness, drowsiness, tinnitus. The safety and effectiveness of prilocaine depend on proper dosage, correct technique, adequate precautions, and readiness for emergencies.
Propitocaine hydrochloride Preparation Products And Raw materials
Global( 390)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| NILKANTH HEALTH CHEM (I) PRIVATE LIMITED | +91 8000452862 | Gujarat, India | 17 | 58 | Inquiry |
| NB Healthcare Pvt Ltd | +91 7227055467 | Gujarat, India | 37 | 58 | Inquiry |
| SNECOFRi Pvt Ltd | +91-9032850129 +91-9032850129 | Telangana, India | 404 | 58 | Inquiry |
| Chynops Pharma | +919998000404 | Gujarat, India | 39 | 58 | Inquiry |
| Apex Healthcare Limited | +9199825711244 | Gujarat, India | 22 | 58 | Inquiry |
| Chemino Pharma Ltd | +91-8689897373 +91-8689897373 | Maharashtra, India | 31 | 58 | Inquiry |
| Anugraha Chemicals | +91-8041685494 +91-9845939733 | Karnataka, India | 22 | 58 | Inquiry |
| Amuna Pharmaceuticals LLP | +91-7940397667 +91-8700823105 | Gujarat, India | 14 | 58 | Inquiry |
| Rivashaa Agrotech Biopharma Pvt. Ltd. | +91-26463395 +91-7926462688 | Gujarat, India | 1615 | 58 | Inquiry |
| Acute Research | +91-9825068697 +91-9825068697 | Gujarat, India | 43 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| NILKANTH HEALTH CHEM (I) PRIVATE LIMITED | 58 |
| NB Healthcare Pvt Ltd | 58 |
| SNECOFRi Pvt Ltd | 58 |
| Chynops Pharma | 58 |
| Apex Healthcare Limited | 58 |
| Chemino Pharma Ltd | 58 |
| Anugraha Chemicals | 58 |
| Amuna Pharmaceuticals LLP | 58 |
| Rivashaa Agrotech Biopharma Pvt. Ltd. | 58 |
| Acute Research | 58 |
Related articles
- Propitocaine hydrochloride: mechanism of action, clinical applications and side effects
- Propitocaine hydrochloride is a local anesthetic that blocks nerve impulses, providing temporary pain relief during various me....
- Nov 22，2023
- Prilocaine Hydrochloride--Metabolism,Excretion,Pediatric use, Biological Functions
- Prilocaine hydrochloride (Citanest) is an amide anesthetic whose onset of action is slightly longer than that of lidocaine; it....
- Oct 12，2020
1786-81-8(Propitocaine hydrochloride )Related Search:
2-(propylamino)-o-propionotoluidide hydrochloride
2-(propylamino)-o-propionotoluididmonohydrochloride
alpha-propylamine-2-methyl-propionanilidehydrochloride
citanesthydrochloride
l-67hydrochloride
Prilocaine HCL //Prilocaine
N-(o-tolyl)-2-(propylamino)propionamide hydrochloride
Prilocaine hydrochloride,N-(2-Methylphenyl)-2-(propylamino)propanamide hydrochloride
Prilocaine Hydrochloride (200 mg)
Prilocaine HC
n-(2-methylphenyl)-2-(propylamino)-propanamidmonohydrochloride
prilocainechloride
xylonest
PRILOCAINE HCL
PRILOCAINE HYDROCHLORIDE
propitocaine hydrochloride
N-(2-METHYLPHENYL)-2-(PROPYLAMINO)PROPANAMIDE HYDROCHLORIDE
Propitocaine HCL
2-(propylaMino)-N-(o-tolyl)propanaMide hydrochloride
Prilocaine hydrochloride, >=99%
PRILOCAINE HYDROCHLORIDE USP
PRILOCAINE HYDROCHLORIDE ASSAY STANDARD BP(CRM STANDARD)
PRILOCAINE HYDROCHLORIDE BP STANDARD
PRILOCAINE HYDROCHLORIDE BP STANDARD(CRM STANDARD)
PRILOCAINE HYDROCHLORIDE EPP
PRILOCAINE HYDROCHLORIDE EPP(CRM STANDARD)
PRILOCAINE HYDROCHLORIDE MM
PRILOCAINE HYDROCHLORIDE MM(CRM STANDARD)
PrilocaineHydrochloroide
Propanamide, N-(2-methylphenyl)-2-(propylamino)-, monohydrochloride
PRILOCAINI HVDROCHLORIDUM
a-(Propylamino)-2-methylpropionanilide hydrochloride
Citanest Plain
o-Propionotoluidide, 2-(propylamino)-, monohydrochloride (8CI)
Propanamide, N-(2-methylphenyl)-2-(propylamino)-, monohydrochloride (9CI)
Prilocaine for peak identification
N1-(2-methylphenyl)-N2-propylalaninamide hydrochloride
Ropitocaine Hcl
Prilocaine hydrochloride, 99%, a local anesthetic of the amino amide type
Ropitocaine hydrochloride
Prilocaine Hydrochloride >
Prilocaine Hydrochloride /Prilocaine HCL
Propanamide, N-(2-methylphenyl)-2-(propylamino)-, hydrochloride (1:1)
2-(Propylamino)-N-(o-tolyl)propionamide Hydrochloride
Propitocaine hydrochloride USP/EP/BP
Prilocaine hydrochloride salt
Prilocaine hydrochloride, Pharma
prilocaine HCL powder
Prilocaine HydrochlorideQ: What is
Prilocaine Hydrochloride Q: What is the CAS Number of
Prilocaine Hydrochloride Q: What is the storage condition of
Prilocaine Hydrochloride Q: What are the applications of
Prilocaine Hydrochloride
Prilocaine Hydrochloride (1561008)
Prilocaine HCI
Prilocaine HCl
IP/USP/BP/EP
Prilocaine Hydrochloride, ≥ 98.0%
Prilocaine HCl|||Propitocaine hydrochloride|||Xylonest
Propylcaine hydrochloride
1786-81-8
C13H20N2OHCl
C13H21ClN2O