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PF06869206

PF06869206 Structure
CAS No.
2227425-05-8
Chemical Name:
PF06869206
Synonyms
CS-2762;PF06869206;PF-06869206;PF-06869206; PF 06869206; PF06869206;inhibit,PF-06869206,Na+ channels,Sodium Channel,Na channels,PF 06869206,Inhibitor,PF06869206;(S)-3-Chloro-7-(2-(hydroxymethyl)morpholino)-2-methyl-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile;1H-Pyrrolo[3,2-b]pyridine-6-carbonitrile, 3-chloro-7-[(2S)-2-(hydroxymethyl)-4-morpholinyl]-2-methyl-5-(trifluoromethyl)-
CBNumber:
CB04187431
Molecular Formula:
C15H14ClF3N4O2
Molecular Weight:
374.75
MOL File:
2227425-05-8.mol
Modify Date:
2024/7/2 8:54:58
Request For Quotation

PF06869206 Properties

Boiling point 599.2±50.0 °C(Predicted)
Density 1.57±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMF: 1 mg/mL; DMSO: 1mg/mL; Ethanol: 10mg/mL; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/mL
form A crystalline solid
pka 11.78±0.40(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

PF06869206 Chemical Properties,Uses,Production

Description

PF-06869206 is an orally bioavailable inhibitor of sodium-phosphate cotransporter 2a (NaPi2a; IC50 = 380 nM). It is selective for NaPi2a over NaPi2b, NaPi2c, PiT-1, and PiT-2 (IC50s = >25 μM).

PF06869206 Preparation Products And Raw materials

Raw materials

Preparation Products

PF06869206 Suppliers

Global( 41)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Wuhan Jingkang en Biomedical Technology Co., Ltd +8613720134139 China 4694 58 Inquiry
Bide Pharmatech Ltd. 400-1647117 15221909166 China 63720 58 Inquiry
InvivoChem 13549236410 China 6749 58 Inquiry
Shanghai SuperLan Chemcial Technique Centre 021-2022843681 15618226720 China 8931 58 Inquiry
Olix (Shanghai) Pharmaceutical Technology Co., Ltd 17316404525 China 9649 58 Inquiry
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 60
Career Henan Chemica Co 58
Zhejiang J&C Biological Technology Co.,Limited 58
InvivoChem 58
Aladdin Scientific 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 58
Bide Pharmatech Ltd. 58
InvivoChem 58
Shanghai SuperLan Chemcial Technique Centre 58
Olix (Shanghai) Pharmaceutical Technology Co., Ltd 58

PF06869206 Spectrum

PF06869206(2227425-05-8)1HNMR

2227425-05-8(PF06869206)Related Search:

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PF06869206 PF-06869206 CS-2762 PF-06869206; PF 06869206; PF06869206 1H-Pyrrolo[3,2-b]pyridine-6-carbonitrile, 3-chloro-7-[(2S)-2-(hydroxymethyl)-4-morpholinyl]-2-methyl-5-(trifluoromethyl)- (S)-3-Chloro-7-(2-(hydroxymethyl)morpholino)-2-methyl-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile inhibit,PF-06869206,Na+ channels,Sodium Channel,Na channels,PF 06869206,Inhibitor,PF06869206 2227425-05-8