4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide
![4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide Structure](CAS/GIF/947303-87-9.gif)
- CAS No.
- 947303-87-9
- Chemical Name:
- 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide
- Synonyms
- CS-122;PF 429242;-4-((Diethylamino);PF-429242;PF429242;-N-(pyrrolidin-3-yl);-N-(2-methoxyphenethyl);PF-429242 dihydrochloride;PF-429242 (hydrochloride);4-((diethylaMino)Methyl)-N-(2-Methoxyphenethyl)-N-(pyrrolidin-3-yl)benzaMide;o)Meth (2-MetR)-4-((diethylaMinyl)-Nhoxyphenethyl)-N-(pyrrolidin-3-yl)benzaMide
- CBNumber:
- CB12554348
- Molecular Formula:
- C25H35N3O2
- Molecular Weight:
- 409.57
- MOL File:
- 947303-87-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/18 11:31:11
Boiling point | 562.2±50.0 °C(Predicted) |
---|---|
Density | 1.11±0.1 g/cm3(Predicted) |
storage temp. | Sealed in dry,2-8°C |
solubility | H2O: soluble15mg/mL, clear |
form | powder |
pka | 9.47±0.10(Predicted) |
color | white to beige |
InChIKey | XKPJTOHUPQWSOJ-HSZRJFAPSA-N |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() GHS07,GHS09 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335-H410 |
Precautionary statements | P273-P302+P352-P305+P351+P338 |
Hazard Codes | Xi,N |
Risk Statements | 36/37/38-50 |
Safety Statements | 26-61 |
RIDADR | UN 3077 9 / PGIII |
WGK Germany | 3 |
4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide price More Price(2)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SML0667 | PF-429242 dihydrochloride ≥98% (HPLC) | 947303-87-9 | 5MG | ₹15209.13 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML0667 | PF-429242 dihydrochloride ≥98% (HPLC) | 947303-87-9 | 25MG | ₹61258.68 | 2022-06-14 | Buy |
4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide Chemical Properties,Uses,Production
Uses
PF 429242 is a novel subtilisin kexin isozyme-1/site-1 (SKI-1/S1P) protease inhibitor. PF 429242 is a sterol regulatory element-binding protein1 (SREBP1) inhibitor and has been shown to decrease pancreatic cancer cell viability and proliferation.
Biochem/physiol Actions
PF-429242 is a potent inhibitor of S1P (cellular proprotein convertase sterol regulatory element-binding protein (SREBP) site 1 protease) that reduces expression levels of hepatic SREBP target genes and lower rates of cholesterol and fatty acid synthesis in mice. PF-429242 is a potent antiviral agent against prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) and LASV in cultured cells. PF-429242 efficiently prevented the processing of GPC from the LCMV and LASV. PF-429242 is expected to be active against CCHFV.
4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
Amadis Chemical Company Limited | 571-89925085 | China | 131980 | 58 | Inquiry |
Twochem Co.Ltd | 021-021-58111628 15800915896 | China | 304 | 55 | Inquiry |
Matrix Scientific | 803 788-9494 All other calls | United States | 6655 | 80 | Inquiry |
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