D-DOPA

- CAS No.
- 5796-17-8
- Chemical Name:
- D-DOPA
- Synonyms
- 3,4-DIHYDROXY-D-PHENYLALANINE;D-DOPA;Dextrodopa;D-DOPA USP/EP/BP;3-Hydroxytyrosine;D-3-HYDROXYTYROSINE;3-HYDROXY-D-TYROSINE;H-D-TYR(3-HYDROXY)-OH;D-Tyrosine,3-hydroxy-;3-hydroxy-tyrosine -D-
- CBNumber:
- CB0470294
- Molecular Formula:
- C9H11NO4
- Molecular Weight:
- 197.19
- MOL File:
- 5796-17-8.mol
- Modify Date:
- 2025/1/27 9:38:02
Melting point | 276-278 °C(lit.) |
---|---|
alpha | D11 +13.0° (c = 5.27 in 1N HCl) |
Boiling point | 448.4±45.0 °C(Predicted) |
Density | 1.468±0.06 g/cm3(Predicted) |
storage temp. | -20°C |
solubility | 0.5 M HCl: soluble |
pka | 2.24±0.20(Predicted) |
form | powder |
color | white to tan |
Merck | 13,3454 |
BRN | 2417637 |
Stability | Hygroscopic |
CAS DataBase Reference | 5796-17-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H335-H319 | |||||||||
Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P | |||||||||
WGK Germany | 3 | |||||||||
F | 10-23 | |||||||||
HS Code | 2922500090 | |||||||||
NFPA 704 |
|
D-DOPA price More Price(2)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | D9378 | 3,4-Dihydroxy-D-phenylalanine powder, ≥95% | 5796-17-8 | 250MG | ₹23760.88 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D9378 | 3,4-Dihydroxy-D-phenylalanine powder, ≥95% | 5796-17-8 | 1G | ₹71964.6 | 2022-06-14 | Buy |
D-DOPA Chemical Properties,Uses,Production
Chemical Properties
Tan Solid
Uses
D-DOPA (Levodopa EP Impurity D) is a DOPA enantiomer that lacks biological activity.
Definition
ChEBI: The D-enantiomer of dopa.
Purification Methods
Likely impurities are vanillin, hippuric acid, 3-methoxytyrosine and 3-aminotyrosine. DOPA recrystallises from large volumes of H2O forming colourless white needles; its solubility in H2O is 0.165%, but it is insoluble in EtOH, *C6H6, CHCl3, and EtOAc. Also crystallise it by dissolving it in dilute HCl and adding dilute ammonia to give pH 5, under N2. Alternatively, crystallise it from dilute aqueous EtOH. It is rapidly oxidised in air when moist, and darkens, particularly in alkaline solution. Dry it in vacuo at 70o in the dark, and store it in a dark container preferably under N2. It has at 220.5nm (log 3.79) and 280nm (log 3.42) in 0.001N max HCl. [Yamada et al. Chem Pharm Bull Jpn 10 693 1962, Bretschneider et al. Helv Chim Acta 56 2857 1973, NMR: Jardetzky & Jardetzky J Biol Chem 233 383 1958, Beilstein 4 IV 2492, 2493.]
D-DOPA Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
KARPSCHEM LABORATORIES | +91-7249203006 +91-7249203006 | Maharashtra, India | 786 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6739 | 58 | Inquiry |
SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6514 | 58 | Inquiry |
Hebei Chuanghai Biotechnology Co., Ltd | +8615531157085 | China | 8808 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29858 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49732 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 32159 | 58 | Inquiry |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | China | 34563 | 58 | Inquiry |
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