ChemicalBook > Product Catalog >API >Circulatory system drugs >Antihypertensive drugs >alpha-Methyldopa sesquihydrate
alpha-Methyldopa sesquihydrate
- CAS No.
- 41372-08-1
- Chemical Name:
- alpha-Methyldopa sesquihydrate
- Synonyms
- (S)-2-AMINO-3-(3,4-DIHYDROXYPHENYL)-2-METHYLPROPIONIC ACID SESQUIHYDRATE;C07194;hyperpax;IDI1_000142;Prestwick2_;KBio2_001417;KBio2_003985;KBio2_006553;KBio3_001521;SPBio_001056
- CBNumber:
- CB7135325
- Molecular Formula:
- C10H15NO5
- Molecular Weight:
- 229.23
- MOL File:
- 41372-08-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:15
| Melting point | >300 °C(lit.) |
|---|---|
| storage temp. | 2-8°C |
| solubility | Slightly soluble in water, very slightly soluble in ethanol (96 per cent). It is freely soluble in dilute mineral acids. |
| form | Solid |
| color | White to Off-White |
| optical activity | [α]25/D 13°, c = 1 in H2O |
| Water Solubility | 0.1-1 g/100 mL at 23 ºC |
| Sensitive | Air & Light Sensitive |
| Merck | 13,6080 |
| BRN | 2417244 |
| Stability | Stable, but may be light sensitive. Very hygroscopic. Undergoes catalytic oxygenation in the presence of magnesium, cupric, cobalt, nickel and ferric ions. Store under a dry atmosphere. |
| CAS DataBase Reference | 41372-08-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P280-P305+P351+P338 | |||||||||
| Risk Statements | 20/21-36/37/38-42/43-65 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | YP2860000 | |||||||||
| F | 10-23 | |||||||||
| HS Code | 2922504500 | |||||||||
| NFPA 704 |
|
alpha-Methyldopa sesquihydrate price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | PHR2672 | Methyldopa Pharmaceutical Secondary Standard; Certified Reference Material | 41372-08-1 | 1G | ₹28404.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 857416 | (−)-3-(3,4-Dihydroxyphenyl)-2-methyl-L-alanine sesquihydrate 99% | 41372-08-1 | 5G | ₹5769.73 | 2022-06-14 | Buy |
alpha-Methyldopa sesquihydrate Chemical Properties,Uses,Production
Chemical Properties
White Solid
Purification Methods
Recrystallise methyldopa from H2O. [Reinhold et al. J Org Chem 33 1209 1968.] The L-isomer forms a sesquihydrate from H2O m 302-304o (dec), and the anhydrous crystals are hygroscopic,[] 23D -4.0o (c 1, 0.1N HCl), []546 +154.5o (c 5, CuSO4 solution). It has max at 281nm ( 2780). Its solubility in H2O at 25o is ~10mg/mL and the pH of an aqueous solution is ~5.0. It is insoluble in most organic solvents. [Stein et al. J Am Chem Soc 77 700 1955, Beilstein 4 IV 2505.]
alpha-Methyldopa sesquihydrate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 285)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Ebenezer Industries | Gujarat, India | 96 | 58 | Inquiry | |
| Kotaru Laboratories Private Limited | 91--9849999231 | Hyderabad, India | 22 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| JSK Chemical | 98797 67970 | Gujarat, India | 291 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Opulent Pharma | 08068441147Ext 981 | Gujarat, India | 810 | 58 | Inquiry |
| Ebenezer Industries | 91--7600807590 | Gujarat, India | 53 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Ebenezer Industries | 58 |
| Kotaru Laboratories Private Limited | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| A.J Chemicals | 58 |
| Pharmaffiliates Analytics and Synthetics P. Ltd | 58 |
| JSK Chemical | 58 |
| SynZeal Research Pvt Ltd | 58 |
| Opulent Pharma | 58 |
| Ebenezer Industries | 58 |
| Pharma Affiliates | 58 |
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