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Bufotenine

Bufotenine Structure
CAS No.
487-93-4
Chemical Name:
Bufotenine
Synonyms
Cohoba;DM5-HT;Mapine;Mappin;NSC 89;Mappine;bufotenin;BUFOTENINE;Bafotenine;Buffoonish
CBNumber:
CB0471554
Molecular Formula:
C12H16N2O
Molecular Weight:
204.27
MOL File:
487-93-4.mol
MSDS File:
SDS
Modify Date:
2023/5/4 17:41:45

Bufotenine Properties

Melting point 62-64°C
Boiling point bp0.1 320°
Density 1.0565 (rough estimate)
refractive index 1.6000 (estimate)
Flash point 2℃
storage temp. Refrigerator, Under Inert Atmosphere
solubility Bufotenine is soluble in dilute acids and alkalis.
pka 10.11±0.40(Predicted)
EPA Substance Registry System 1H-Indol-5-ol, 3-[2-(dimethylamino)ethyl]- (487-93-4)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H302+H312+H332-H319
Precautionary statements  P210-P280-P305+P351+P338
Hazard Codes  F,Xn
Risk Statements  11-20/21/22-36
Safety Statements  16-36/37
RIDADR  1544
WGK Germany  2
HazardClass  6.1(b)
PackingGroup  III
DEA Controlled Substances CSCN: 7433
CSA SCH: Schedule I
NARC: No

Bufotenine Chemical Properties,Uses,Production

Chemical Properties

Bufotenine is an indole alkaloid obtained from the seeds and leaves of Piptadenia peregrine and P. macrocarpa. It has also been isolated from the skin glands of toads (Bufo species). The base is typically seen as white crystalline powder and the oxalate hydrate as a lavender to brown powder. The oxalate hydrate is slightly soluble in chloroform and can be separated from chloroform insoluble material for analysis.

History

Bufotenin was isolated from toad skin, and named by the Austrian chemist Handovsky at the University of Prague during World War I.The structure of bufotenine was confirmed in 1934 by Heinrich Wieland's laboratory in Munich, and the first reported synthesis of bufotenine was by Toshio Hoshino and Kenya Shimodaira in 1935.

Uses

Controlled substance (hallucinogen).
Bufotenine is a hallucinogenic serotonin analog found in frog and toad skins, mushrooms, plants and some mammals (especially in the brains, plasma, and urine of schizophrenics). It is a potent hallucinogen used in its natural state by several shaman sects and in some drug abuse situations in the United States and Australia. It causes schizophrenia and other psychotic symptoms.

Definition

ChEBI: Bufotenine is a tertiary amine that consists of N,N-dimethyltryptamine bearing an additional hydroxy substituent at position 5. It has a role as a hallucinogen and a coral metabolite. It is a tryptamine alkaloid and a tertiary amine. It derives from a N,N-dimethyltryptamine.

Bufotenine Preparation Products And Raw materials

Raw materials

Preparation Products

Bufotenine Suppliers

Global( 41)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Triveni chemicals 08048762458 New Delhi, India 6093 58 Inquiry
Abintio Biosciences 08048372058Ext 514 Hyderabad, India 52 58 Inquiry
Chengdu Biopurify Phytochemicals Ltd. +86-28-82633860 +86-18080483897 China 3424 58 Inquiry
Shaanxi Didu New Materials Co. Ltd +86-89586680 +86-13289823923 China 9003 58 Inquiry
SUZHOU SENFEIDA CHEMICAL CO.,LTD +86-0512-83500002 +8615195660023 China 23053 58 Inquiry
Hubei CuiRan Biotechnology Co., Ltd. 181-86211184 18162791556 China 4351 58 Inquiry
Shanghai Yihe Biological Technology Co., Ltd. 17721395025 China 3422 58 Inquiry
Shanghai Standard Technology Co.,Ltd. 021-021-57127007-6622-6622 15618937986 China 3016 58 Inquiry
Wuhan ChemFaces Biochemical Co., Ltd. 18607101326 15172504745 China 7059 55 Inquiry
BUFOTENINE 1H-Indol-5-ol, 3-[2-(dimethylamino)ethyl]- 3-(2-(dimethylamino)ethyl)-indol-5-o 3-(2-dimethylaminoethyl)-5-indolol 3-(beta-dimethylaminoethyl)-5-hydroxyindole 3-[2-(Dimethylamino)ethyl]-1H-indol-5-ol 3-[2-(Dimethylamino)ethyl]-5-indolol 3-[2-(Dimethylamino)ethyl]indol-5-ol 3-[beta-(Dimethylamino)ethyl]-5-hydroxyindole 5-Hydroxy-N,N-dimethyltryptamine bufotenin Cinobufotenine Cohoba Dimethylserotonin DM5-HT Indol-5-ol, 3-[2-(dimethylamino)ethyl]- Mapine Mappin Mappine N,N-Dimethyl-5-hydroxytryptamine N,N-Dimethylserotonin Bafotenine 3-[2-(Dimethylamino)ethyl]-5-hydroxy-1H-indole 3-(β-DiMethylaMinoethyl)-5-hydroxyindole NSC 89 Bufotenine solution Buffoonish 487-93-4 Amines Aromatics Heterocycles