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SARPAGINE

SARPAGINE Structure
CAS No.
482-68-8
Chemical Name:
SARPAGINE
Synonyms
Raupin;Raupine;SARPAGINE;sarpagan-10,17-diol;Sarpagane-10,17-diol
CBNumber:
CB6174505
Molecular Formula:
C19H22N2O2
Molecular Weight:
310.39
MOL File:
482-68-8.mol
MSDS File:
SDS
Modify Date:
2023/4/23 13:52:06

SARPAGINE Properties

Melting point 320°C
Boiling point 450.55°C (rough estimate)
alpha D20 +54° (c = 0.5 in pyridine)
Density 1.1396 (rough estimate)
refractive index 1.5600 (estimate)
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Powder
pka 10.24±0.40(Predicted)

SAFETY

Risk and Safety Statements

RIDADR  1544
HazardClass  6.1(b)
PackingGroup  III

SARPAGINE Chemical Properties,Uses,Production

Description

This base has been isolated from Rauwolfia serpentina and is an isomer of Ajmalinine (q.v.). Pharmacologically it has between three and four times the effect of the total Rauwolfia alkaloids on isolated rabbit uterus and is very specific. In the cat, the blood pres~ure is lowered by 0.5-2.0 mgm per kilo body weight. The toxicity is low.

Definition

ChEBI: An indole alkaloid that is sarpagan bearing hydroxy groups at positions 10 and 17.

References

Bodendorf, Eder., Naturwis<., 40, 342 (1953)

SARPAGINE Preparation Products And Raw materials

Raw materials

Preparation Products

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SARPAGINE sarpagan-10,17-diol Raupine Sarpagane-10,17-diol Raupin 482-68-8 Alkaloids