Clobetasone butyrate
![Clobetasone butyrate Structure](CAS/GIF/25122-57-0.gif)
- CAS No.
- 25122-57-0
- Chemical Name:
- Clobetasone butyrate
- Synonyms
- eumovate;Clobetasone-17-butyrate;sn203;Emovate;CCl 5537;molivate;GR 2/1214;Kindavate;(16-beta)-);17-Butyrate
- CBNumber:
- CB0497976
- Molecular Formula:
- C26H32ClFO5
- Molecular Weight:
- 478.98
- MOL File:
- 25122-57-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:54:58
Melting point | 90-100° |
---|---|
Boiling point | 573.3±50.0 °C(Predicted) |
Density | 1.1736 (estimate) |
storage temp. | Refrigerator, Under Inert Atmosphere |
solubility | Practically insoluble in water, freely soluble in acetone and in methylene chloride, slightly soluble in ethanol (96 per cent). |
form | Solid |
color | White to Off-White |
Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
InChIKey | FBRAWBYQGRLCEK-JGSYYNBSNA-N |
SMILES | [C@]1(C(=O)CCl)(OC(=O)CCC)[C@@H](C)C[C@@]2([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)C(=O)C[C@]12C |&1:0,11,14,16,26,28,33,r| |
CAS DataBase Reference | 25122-57-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS08 |
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Signal word | Warning | |||||||||
Hazard statements | H351 | |||||||||
Precautionary statements | P280 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 40 | |||||||||
Safety Statements | 22-36 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | TU4154083 | |||||||||
HS Code | 29372290 | |||||||||
Toxicity | mouse,LD50,intraperitoneal,500mg/kg (500mg/kg),Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 14, Pg. 838, 1983. | |||||||||
NFPA 704 |
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Clobetasone butyrate price More Price(4)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | C5548 | Clobetasone butyrate ≥98% | 25122-57-0 | 100MG | ₹5899.63 | 2022-06-14 | Buy |
TCI Chemicals (India) | C3510 | Clobetasone Butyrate | 25122-57-0 | 50MG | ₹1800 | 2022-05-26 | Buy |
TCI Chemicals (India) | C3510 | Clobetasone Butyrate | 25122-57-0 | 250MG | ₹4600 | 2022-05-26 | Buy |
TCI Chemicals (India) | C3510 | Clobetasone Butyrate | 25122-57-0 | 1G | ₹8000 | 2022-05-26 | Buy |
Clobetasone butyrate Chemical Properties,Uses,Production
Chemical Properties
White or almost white powder.
Uses
Clobetasone butyrate is a synthetic glucocorticoid which is used as an anti-inflammatory in the treatment of various skin disorders. As a steroid medicine, it can used on the skin to treat swelling, itching and irritation. Such as eczema, including ;contact dermatitis; psoriasis; insect bites and stings; nappy rash.
Mechanism of action
Topical corticosteroids (Clobetasone butyrate) inhibit the migration of macrophages and leukocytes into areas of inflamed skin by reversing vascular dilation and permeability, resulting in decreased erythema, edema and pruritus.
Side effects
Some people get a burning or stinging feeling for a few minutes when they put clobetasone cream or ointment on their skin. Clobetasone cream contains cetostearyl alcohol and chlorocresol, which may cause local skin reactions or allergic reactions.
Clobetasone butyrate Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Halcyon Labs Pvt. Ltd | +919833750169 | Mumbai, India | 17 | 58 | Inquiry |
Gonane Pharma | +91-9819380043 +91-9819380043 | NaviMumbai, India | 192 | 58 | Inquiry |
Anuh Pharma Ltd (SK GROUP) | +912266227575 | Maharashtra, India | 38 | 58 | Inquiry |
Horster Biotek Pvt Ltd | +91-7359657360 +91-9898127219 | Gujarat, India | 58 | 58 | Inquiry |
Dayaram Pharma Chem | +91-9601766800 +91-9601766800 | Gujarat, India | 61 | 58 | Inquiry |
Stermone Chemicals Pvt Ltd | +91-9328939700 +91-9328939700 | Gujarat, India | 20 | 58 | Inquiry |
Avik Pharmaceutical Limited | +91-9821827247 +91-7600019006 | Maharashtra, India | 22 | 58 | Inquiry |
Bhugan Lifescience Pvt Ltd | +91-9909430337 +91-8849461798 | Gujarat, India | 23 | 58 | Inquiry |
Unimax Chemicals Pvt Ltd | +91-9819363200 +91-9963474090 | Maharashtra, India | 21 | 58 | Inquiry |
Medilink Pharmachem | +91 (79) 3007-0133 | New Delhi, India | 424 | 50 | Inquiry |
Supplier | Advantage |
---|---|
Halcyon Labs Pvt. Ltd | 58 |
Gonane Pharma | 58 |
Anuh Pharma Ltd (SK GROUP) | 58 |
Horster Biotek Pvt Ltd | 58 |
Dayaram Pharma Chem | 58 |
Stermone Chemicals Pvt Ltd | 58 |
Avik Pharmaceutical Limited | 58 |
Bhugan Lifescience Pvt Ltd | 58 |
Unimax Chemicals Pvt Ltd | 58 |
Medilink Pharmachem | 50 |
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