Chlorobutanol
- CAS No.
- 1320-66-7
- Chemical Name:
- Chlorobutanol
- Synonyms
- (0.5 H2O);Chlorobutanol;Chlorobutanol CRS;Butene chlorohydrin;Chlorobutanol(0.5H2O);β,β,β-trichloro-tert-butyl;Trichlorot-butyl alcohol hemihydrate
- CBNumber:
- CB0512284
- Molecular Formula:
- C4H7Cl3O
- Molecular Weight:
- 177.46
- MOL File:
- 1320-66-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/9/13 17:49:43
| Flash point | 100 °C |
|---|---|
| storage temp. | Sealed in dry,Room Temperature |
| Odor | camphoraceous odor |
| CAS DataBase Reference | 1320-66-7(CAS DataBase Reference) |
| EPA Substance Registry System | Butanol, chloro- (1320-66-7) |
SAFETY
Risk and Safety Statements
| Hazard Codes | Xn |
|---|---|
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-36/37/39 |
Chlorobutanol Chemical Properties,Uses,Production
Chemical Properties
Crystalline solid with a camphor-like odorand taste; sublimes; mp 97°C (206°F)(hemihydrate 78°C (172°F)); bp 167°C(332°F); soluble in water and organic solvents..
Uses
Chlorobutanol is used as a plasticizer forcellulose esters, as a preservative for hypodermic solutions, and in veterinary medicineas a mild sedative and antiseptic.
Health Hazard
Chlorobutanol exhibited moderate toxicity intest animals. A lethal dose by oral intake indogs and rabbits were 238 and 213 mg/kg,respectively (NIOSH 1986). The toxic symptoms are not reported. This compound isa mild skin and eye irritant and may bemutagenic.
Clinical Use
1,1,1-Trichloro-2-methyl-2-propanol is a white crystallinesolid with a camphorlike aroma. It occurs in an anhydrousform and a hemihydrate form, both of which sublime at roomtemperature and pressure. Chlorobutanol is slightly soluble inwater and soluble in alcohol and in organic solvents.
Chlorobutanol is used as a bacteriostatic agent in pharmaceuticalsfor injection, ophthalmic use, and intranasal administration.It is unstable when heated in aqueous solution, especially at pH greater than 7. Under these conditions,chlorobutanol undergoes elimination. Solutions with a pHof approximately 5 are reasonably stable at 25°C.Chlorobutanol is stable in oils and organic solvents.
Waste Disposal
A suitable method of destruction of chlorobu tanol is the burning of its solution in a com bustible solvent in a chemical incinerator.
Chlorobutanol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 | China | 5873 | 58 | Inquiry |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | China | 2931 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | China | 34571 | 58 | Inquiry |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | China | 23556 | 58 | Inquiry |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | China | 15395 | 58 | Inquiry |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | China | 52861 | 58 | Inquiry |
| Zhuoer Chemical Co., Ltd | 02120970332; +8613524231522 | China | 2905 | 58 | Inquiry |
| CD Chemical Group Limited | +8615986615575 | China | 20356 | 58 | Inquiry |