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2',3',5'-Tri-O-acetyluridine

CAS No.: 4105-38-8

Chemical Name:: 2',3',5'-Tri-O-acetyluridine

Synonyms: TAU;Uridine triacetate;(2R,3R,4R,5R)-2-(AcetoxyMethyl)-5-(2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate;MTBT1;MAPTL;RG 2133;Vistonuridine;2',3',5'-TriacetyL;Tri-O-acetyl uridine;2',3',5'-Tri-O-acety

CBNumber:: CB0687805

Molecular Formula:: C15H18N2O9

Molecular Weight:: 370.31

MOL File:: 4105-38-8.mol

Modify Date:: 2024/6/4 15:29:52

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2',3',5'-Tri-O-acetyluridine Properties

Melting point	127.0 to 131.0 °C
Density	1.43±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,Store in freezer, under -20°C
solubility	Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly)
form	Solid
pka	9.39±0.10(Predicted)
color	Off-White
InChI	InChI=1S/C15H18N2O9/c1-7(18)23-6-10-12(24-8(2)19)13(25-9(3)20)14(26-10)17-5-4-11(21)16-15(17)22/h4-5,10,12-14H,6H2,1-3H3,(H,16,21,22)/t10-,12-,13-,14-/m1/s1
InChIKey	AUFUWRKPQLGTGF-QRMSVCKNSA-N
SMILES	C(OC(=O)C)[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](OC(=O)C)[C@@H]1OC(=O)C
CAS DataBase Reference	4105-38-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Safety Statements	24/25
WGK Germany	3
HS Code	29349990

2',3',5'-Tri-O-acetyluridine price More Price(4)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	SAB1306711	ANTI-TAU(C-TERMINAL) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution	4105-38-8	400μL	₹47796.6	2022-06-14	Buy
Sigma-Aldrich(India)	SAB1306682	ANTI-TAU (MAPT) (S720) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution	4105-38-8	400μL	₹47796.6	2022-06-14	Buy
TCI Chemicals (India)	T2549	2',3',5'-Tri-O-acetyluridine	4105-38-8	5G	₹6800	2022-05-26	Buy
TCI Chemicals (India)	T2549	2',3',5'-Tri-O-acetyluridine	4105-38-8	25G	₹15000	2022-05-26	Buy

Product number	Packaging	Price	Buy
SAB1306711	400μL	₹47796.6	Buy
SAB1306682	400μL	₹47796.6	Buy
T2549	5G	₹6800	Buy
T2549	25G	₹15000	Buy

2',3',5'-Tri-O-acetyluridine Chemical Properties,Uses,Production

Description

Uridine triacetate is an orally available pro-drug of uridine approved by the FDA for the treatment of the rare autosomal recessive disorder called hereditary orotic aciduria. The drug was also approved for treating overdose of two chemotherapies (fluorouracil and capecitabine). Uridine triacetate was developed by Wellstat Therapeutics and licensed to BTG.

Chemical Properties

White or almost white crystalline powder

Uses

2’,3’,5’-Triacetyluridine is used in the treatment of Alzheimer’s disease in mice and provide neuroprotective effects. Shown to also decrease depressive symptoms and increases in brain pH bipolar patients.

Definition

ChEBI: Uridine triacetate is an acetate ester that is uracil in which the three hydroxy hydrogens are replaced by acetate group. A prodrug for uridine, it is used for the treatment of hereditary orotic aciduria and for management of fluorouracil toxicity. It has a role as a prodrug, a neuroprotective agent and an orphan drug. It is a member of uridines and an acetate ester.

2',3',5'-Tri-O-acetyluridine Preparation Products And Raw materials

Raw materials

Preparation Products

5-Bromouridine 3-METHYL URIDINE

2',3',5'-Tri-O-acetyluridine Suppliers

Global( 307)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
CHEMSWORTH	+91-261-2397244	New Delhi, India	6707	30	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
TCI Chemicals (India) Pvt. Ltd.	1800 425 7889	New Delhi, India	6778	58	Inquiry
Wuhu Nuowei chemistry Co., Ltd.	+86-0553-2911116-802 +undefined17756524438	China	1640	58	Inquiry
Hangzhou Measure Life Technology Co., LTD	+8613343730176	China	83	58	Inquiry
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	China	39916	58	Inquiry
Hebei Mojin Biotechnology Co., Ltd	+86 13288715578 +8613288715578	China	12459	58	Inquiry
Hebei Duling International Trade Co. LTD	+8617333973358	China	15438	58	Inquiry
Ouhuang Engineering Materials (Hubei) Co., Ltd	+86-86177	China	2952	58	Inquiry

Supplier	Advantage
A.J Chemicals	58
CHEMSWORTH	30
Pharmaffiliates Analytics and Synthetics P. Ltd	58
TCI Chemicals (India) Pvt. Ltd.	58
Wuhu Nuowei chemistry Co., Ltd.	58
Hangzhou Measure Life Technology Co., LTD	58
Chongqing Chemdad Co., Ltd	58
Hebei Mojin Biotechnology Co., Ltd	58
Hebei Duling International Trade Co. LTD	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	58

2',3',5'-Tri-O-acetyluridine Spectrum

2',3',5'-Tri-O-acetyluridine(4105-38-8)¹HNMR 2',3',5'-Tri-O-acetyluridine(4105-38-8)IR

4105-38-8(2',3',5'-Tri-O-acetyluridine)Related Search:

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2',3',5'-Triacetylguanosine uridine diphosphate glucose {= UDP-glucose} 2',3',5'-TRI-O-BENZOYLURIDINE Diethyleneglycol diformate 2'-Deoxyuridine

2'-O-Methyluridine (2-ISOPROPOXYETHYL) ACETATE TETRAHYDROFURFURYL ACETATE Uridine Diethyleneglycol diacetate

Uracil 3'-DEOXYURIDINE 1-amino-3-methoxy-propan-2-ol

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2'', 3'', 5''-TRIACETYLURIDINE (2'', 3'', 5''-TRI-O-ACETYLURIDINE) RG 2133 Tri-O-acetyl uridine Vistonuridine 1-((2R,3R,4R,5R)-3,4-Diacetyl-3,4-dihydroxy-5-(1-hydroxy-2-oxopropyl)tetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione 2',3',5'-Tri-O-acetyl-rU 1-((2R,3R,4R,5R)-3,4-Diacetyl-3,4-dihydroxy-5-(1-hydroxy-2-oxopropyl)tetrahydrofuran-2-yl)pyrimid ANTI-TAU(C-TERMINAL) antibody produced in rabbit MAPTL Microtubule-associated protein tau MTBT1 ANTI-TAU (MAPT) (S720) antibody produced in rabbit [4-acetoxy-2-(acetoxymethyl)-5-(2,4-dioxopyrimidin-1-yl)tetrahydrofuran-3-yl] acetate [4-acetyloxy-2-(acetyloxymethyl)-5-( [4-acetyloxy-2-(acetyloxymethyl)-5-(2,4-dioxopyrimidin-1-yl)oxolan-3-yl] acetate 2-(acetoxymethyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate 2-[(acetyloxy)methyl]-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate acetic acid [4-acetoxy-2-(acetoxymethyl)-5-(2,4-diketopyrimidin-1-yl)tetrahydrofuran-3-yl] ester acetic acid [4-acetoxy-2-(acetoxymethyl)-5-(2,4-dioxo-1-pyrimidinyl)-3-tetrahydrofuranyl] ester 1-((2R,3R,4R,5R)-3,4-Diacetyl-3,4-dihydroxy-5-(1-hydroxy-2-oxopropyl)tetrahydrofuran-2-yl)pyri (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4 2',3',5'-tri-O-Acetyluridine≥ 98% (HPLC) URIDINE 2',3',5'-TRIACETATE 2',3',5'-TRI-O-ACETYLURIDINE 2',3',5'-TRIACETYLURIDINE 1-(2-O,3-O,5-O-Triacetyl-β-D-ribofuranosyl)-4-hydroxypyrimidine-2(1H)-one [(2R,3R,4R,5R)-4-acetyloxy-2-(acetyloxymethyl)-5-(2,4-dioxopyrimidin-1-yl)oxolan-3-yl] acetate [(2R,3R,4R,5R)-4-acetyloxy-2-(acetyloxymethyl)-5-(2,4-dioxopyrimidin-1-yl)oxolan-3-yl] ethanoate acetic acid [(2R,3R,4R,5R)-4-acetoxy-2-(acetoxymethyl)-5-(2,4-diketopyrimidin-1-yl)tetrahydrofuran-3-yl] ester 2',3',5'-Tri-O-acety [(2S,3R,4S,5S)-3,4-bis(acetyloxy)-5-(2,4-dioxo-1,2,3,4-tetrahydropyriMidin-1-yl)oxolan-2-yl]Methyl acetate 2',3',5'-Tri0acetyluridine 2`,3`,5`-Tracetyluridine 2',3',5'-Tri-O-acetyl-D-uridine (Ser232) BioAssay&trade Phospho-14-3-3 &theta phosphorylated (S232) 2',3',5'-TriacetyL 2',3',5'-Tri-O-acetyluridine USP/EP/BP Uridine triacetate (2R,3R,4R,5R)-2-(AcetoxyMethyl)-5-(2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate TAU Mouse Anti-Tau antibody 2',3',5'-Tri-O-acetyluridine 2',3',5'-Triacetyluridine 4105-38-8 4105-38-3 C15H18N2O9 Biochemicals and Reagents BioChemical Nucleoside Analogs Nucleosides, Nucleotides, Oligonucleotides