2'-Deoxyuridine
- CAS No.
- 951-78-0
- Chemical Name:
- 2'-Deoxyuridine
- Synonyms
- 2;DU;deoxyuridine;1-((2R,4S,5R)-4-Hydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione;durd;2'-dU;NSC 23615;Uracildeoxyr;Deoxy-uridin;DEOXYURIDINE-2'
- CBNumber:
- CB3472057
- Molecular Formula:
- C9H12N2O5
- Molecular Weight:
- 228.2
- MOL File:
- 951-78-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/25 20:04:51
Melting point | 167-169 °C(lit.) |
---|---|
Boiling point | 370.01°C (rough estimate) |
alpha | D22 +50° (c = 1.1 in N NaOH) |
Density | 1.3705 (rough estimate) |
refractive index | 52 ° (C=1, 1mol/L NaOH) |
storage temp. | Inert atmosphere,2-8°C |
solubility | DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly) |
pka | pKa 9.3(H2O t = 25) (Uncertain) |
form | Powder |
color | White to off-white |
Water Solubility | 300 g/L (20 ºC) |
Sensitive | Air Sensitive |
Merck | 14,2910 |
BRN | 24433 |
InChIKey | MXHRCPNRJAMMIM-ATRFCDNQSA-N |
CAS DataBase Reference | 951-78-0(CAS DataBase Reference) |
EPA Substance Registry System | Uridine, 2'-deoxy- (951-78-0) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H335 | |||||||||
Precautionary statements | P261-P305+P351+P338 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 22-24/25-37/39-36/37/39-26 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | YU7490000 | |||||||||
F | 10-23 | |||||||||
Hazard Note | Air Sensitive | |||||||||
TSCA | Yes | |||||||||
HS Code | 29349990 | |||||||||
NFPA 704 |
|
2'-Deoxyuridine price More Price(9)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | D5412 | 2′-Deoxyuridine ≥98.5% | 951-78-0 | 100MG | ₹2024.28 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D5412 | 2′-Deoxyuridine ≥98.5% | 951-78-0 | 250MG | ₹2998.53 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D5412 | 2′-Deoxyuridine ≥98.5% | 951-78-0 | 1G | ₹7566.68 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D5412 | 2′-Deoxyuridine ≥98.5% | 951-78-0 | 5G | ₹30180.1 | 2022-06-14 | Buy |
TCI Chemicals (India) | D0060 | 2'-Deoxyuridine | 951-78-0 | 1G | ₹1800 | 2022-05-26 | Buy |
2'-Deoxyuridine Chemical Properties,Uses,Production
Description
2'-Deoxyuridine is an intermediate in the synthesis of thymidylate, which is a precursor for DNA synthesis. It has been shown to inhibit the enzymatic activity of enzymes responsible for synthesizing uridine and thymidylate, leading to neuronal death. 2'-Deoxyuridine has been used as a fluorescence probe for nucleic acids and as a polymerase chain reaction (PCR) substrate. It is also known to bind with toll-like receptor 4 (TLR4), which is involved in inflammatory responses.
Chemical Properties
White crystalline powder
Definition
ChEBI: 2'-deoxyuridine is a pyrimidine 2'-deoxyribonucleoside having uracil as the nucleobase. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is functionally related to a uracil.
2'-Deoxyuridine Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
Wuhu Nuowei chemistry Co., Ltd. | +86-0553-2911116-802 +undefined17756524438 | China | 1640 | 58 | Inquiry |
SHANGHAI NOVRIBO BIOTECH | 17821030819 | China | 73 | 58 | Inquiry |
Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 | China | 5959 | 58 | Inquiry |
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