ChemicalBook > Product Catalog >Biochemical Engineering >Nucleoside drugs >Deoxynucleotides and their analogs >Broxuridine
Broxuridine
- CAS No.
- 59-14-3
- Chemical Name:
- Broxuridine
- Synonyms
- BDU;bromodeoxyuridine;5-BRDU;BUDR;BRUDR;BR-DU;5-bdu;5-budr;radibud;NSC-3829
- CBNumber:
- CB2775230
- Molecular Formula:
- C9H11BrN2O5
- Molecular Weight:
- 307.1
- MOL File:
- 59-14-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/10/11 17:37:18
| Melting point | 191-194 °C (dec.)(lit.) |
|---|---|
| alpha | 31 º (c=1, 0.1N NaOH) |
| Density | 1.8573 (rough estimate) |
| refractive index | 22 ° (C=1, H2O) |
| storage temp. | -20°C |
| solubility | NH4OH: 0.1 M at 20 °C, clear, colorless |
| pka | 7.73±0.10(Predicted) |
| form | Crystals or Crystalline Powder |
| color | White to yellow |
| Water Solubility | 1-5 g/100 mL at 22 ºC |
| Merck | 14,1452 |
| BRN | 30395 |
| Stability | Stable, but may be light sensitive. Incompatible with strong oxidizing agents. |
| InChIKey | XMJRLEURHMTTRX-UHFFFAOYSA-N |
| LogP | -0.290 |
| CAS DataBase Reference | 59-14-3(CAS DataBase Reference) |
| EPA Substance Registry System | Uridine, 5-bromo-2'-deoxy- (59-14-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H340-H361fd | |||||||||
| Precautionary statements | P201-P202-P280-P308+P313-P405-P501 | |||||||||
| Hazard Codes | Xn,T | |||||||||
| Risk Statements | 68-36/37/38-63-46-24-61 | |||||||||
| Safety Statements | 36/37/39-26-53-45-36 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | YU7350000 | |||||||||
| F | 10-23 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29349990 | |||||||||
| NFPA 704 |
|
Broxuridine price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | B9285 | 5-Bromo-2′-deoxyuridine BioUltra, ≥99% | 59-14-3 | 50MG | ₹3593.9 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | B5002 | 5-Bromo-2′-deoxyuridine ≥99% (HPLC) | 59-14-3 | 100MG | ₹5758.9 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | B5002 | 5-Bromo-2′-deoxyuridine ≥99% (HPLC) | 59-14-3 | 250MG | ₹7285.23 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | B9285 | 5-Bromo-2′-deoxyuridine BioUltra, ≥99% | 59-14-3 | 250MG | ₹10792.53 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | B5002 | 5-Bromo-2′-deoxyuridine ≥99% (HPLC) | 59-14-3 | 500MG | ₹11052.33 | 2022-06-14 | Buy |
Broxuridine Chemical Properties,Uses,Production
Chemical Properties
White crystalline powder
Uses
A Thymidine analogue used as a mutagen in genetic research. Selectively incorporated into cellular DNA during S-phase
Definition
ChEBI: A pyrimidine 2'-deoxyribonucleoside compound having 5-bromouracil as the nucleobase.
General Description
White crystalline powder.
Air & Water Reactions
Water soluble.
Reactivity Profile
Broxuridine may be heat and light sensitive. .
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition Broxuridine emits very toxic fumes of bromide ion and NOx.
Fire Hazard
Flash point data for Broxuridine are not available; however, Broxuridine is probably combustible.
Safety Profile
Moderately toxic by subcutaneous, intravenous, intraperitoneal, and possibly other routes. Mildly toxic by ingestion. Experimental teratogenic and reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of Brand NOx
Purification Methods
Recrystallise the uridine from EtOH or 96% EtOH. It has max 279 nm at pH 7.0, and 279 nm (log 3.95) at pH 1.9. Its RF values are 0.49, 0.46 and 0.53 in n-BuOH/AcOH/H2O (4:1:1), n-BuOH/EtOH/H2O (40:11:19) and i-PrOH-25% aqueous NH3-H2O (7:1:1), respectively. [Nature 209 230 1966, Pryst.s & Sorm Collect Czech Chem Comm 29 2956 1964, Beilstein 24 III/IV 1234.]
Broxuridine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 377)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| Abintio Biosciences | 08048372058Ext 514 | Hyderabad, India | 52 | 58 | Inquiry |
| Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
| Sisco Resech Laboratories Private Limited | +91-22-4268 5800 | Mumbai, India | 655 | 58 | Inquiry |
| Vyas Bio Life Sciences Pvt. Ltd | -65546373 | Hyderabad, India | 1213 | 58 | Inquiry |
| Oceanic Pharmachem Pvt. Ltd. | 91-22-42128600 | Maharashtra, India | 2006 | 58 | Inquiry |
| Anand Agencies | 91-20-24454597 | Maharashtra, India | 2337 | 58 | Inquiry |
59-14-3(Broxuridine)Related Search:
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5-BROMO-1-(2-DEOXY-BETA-D-RIBOFURANOSYL)URACIL
5-BROMO DEOXYURIDINE
5-BROMO-2'-DESOXYURIDINE
(+)-5-BROMO-2'-DEOXYURIDINE
5-BROMO-2'-DEOXYURIDINE
5-budr
bromouracildeoxyriboside
5-Bromo-1-(2-deoxy-β-D-ribofuranosyl)uracil
5-BROMO-2'-DEOXYURIDINE SIGMAULTRA
5-Bromodeoxyuridine,Crystalline,>98%
Bromo-2'-deoxyuridine
5-Bromo-2'-deoxy-D-uridine
5-BROMO-2-DEOXYURIDINE,ULTRAPURE
5-BROMO-2''-DEOXYURIDINE(5-BRDU)
BROMO-2'-DEOXYURIDINE, 5-(RG)
5-Bromo-2'-deoxyuridine, 99+%
BROMODESOXYURIDINE
5-BROMO-2''-DEOXYURIDINE, HPLC PURIFIED, 98% PURE WITH HPLC UV CHROMATOGRAM
5-BROMO-2''-DEOXYURIDINE CRYSTALLINE
BROMO-2'-DEOXYURIDINE,5-
BRUDR
BROXURIDINE
BR-DU
BRDU LABELING REAGENT
CHEMPACIFIC 52436
5-BROMO-2-DEOXYURIDINE extrapure
5-BrdU, 5-Bromo-1-(2-deoxy-β-D-ribofuranosyl)uracil, 5-Bromouracil deoxyriboside, BUdR
1-(2-deoxy-β-D-ribofuranosyl)-5-bromouracil
5-bdu
5-bromodesoxyuridine
5-bromouracil-2-deoxyriboside
5-bromouracildeoxyriboside
5''-BROMODEOXYURIDINE (BROXURIDINE)
2'-DEOXY-5-BROMOROURIDINE
2'-DEOXY-5-BROMOURIDINE
NSC-3829
radibud
5-Bromo-2’-deoxyridine
5-Bromo-1-(2-deoxy-β-D-ribofuranosyl)uraci
5-Brdu, 5-Bromo-2'-deoxyuridine
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NSC 38297
5-Br-2'--dU
5-Bromo-1-(2-deoxy-beta-D-ribofuranosyl)uracil
5-BrdU
BUdR
l
5-Bromouracil deoxyriboside
5-Bromo-2′-deoxyuridine,5-BrdU, 5-Bromo-1-(2-deoxy-β-D-ribofuranosyl)uracil, 5-Bromouracil deoxyriboside, BUdR
5-broMo-1-[(2S,4R,5S)-4-hydroxy-5-(hydroxyMethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyriMidine-2,4-dione
5-BroMo-3-deoxyuridine
BrdU [5-Bromo-2'-deoxyuridine] *CAS 59-14-3*
5-BrdU5G
Bromodeoxyuridine Cell Proliferation Kit, BioAssay&trade
5-bromo-2-deoxyuridine (BrdU)
5-Bromo-1-(2-deoxy-&beta
-D-ribofuranosyl)uracil
5-Bromo-2'-deoxyuridine>
Uridine, 5-bromo-2'-deoxy-
5-Bromo-1-(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-ylpyrimidine-2,4-dione
Broxuridine USP/EP/BP