Baicalein
![Baicalein Structure](CAS/GIF/491-67-8.gif)
- CAS No.
- 491-67-8
- Chemical Name:
- Baicalein
- Synonyms
- 5,6,7-trihydroxy-2-phenyl-4H-chroMen-4-one;Baicelein;5,6,7-Trihydroxyflavone,97%;BaicaL;Noroxylin;Baicalein;Baicaleine;Baicalein 98%;Baicalein std.;Baicalein (6CI)
- CBNumber:
- CB0738154
- Molecular Formula:
- C15H10O5
- Molecular Weight:
- 270.24
- MOL File:
- 491-67-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/7 16:47:56
Melting point | 256-271 °C (lit.) |
---|---|
Boiling point | 373.35°C (rough estimate) |
Density | 1.3280 (rough estimate) |
refractive index | 1.5000 (estimate) |
storage temp. | Keep in dark place,Sealed in dry,2-8°C |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Yellow solid |
pka | 6.31±0.40(Predicted) |
color | Yellow or yellow-green |
Merck | 14,942 |
BRN | 272683 |
Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week. |
InChIKey | FXNFHKRTJBSTCS-UHFFFAOYSA-N |
LogP | 3.310 (est) |
CAS DataBase Reference | 491-67-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
Hazard Codes | Xi,Xn | |||||||||
Risk Statements | 36/37/38-20/21/22 | |||||||||
Safety Statements | 26-36 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | DJ3100898 | |||||||||
Hazard Note | Irritant | |||||||||
HS Code | 29329990 | |||||||||
NFPA 704 |
|
Baicalein price More Price(10)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 465119 | Baicalein 98% | 491-67-8 | 100MG | ₹2738.73 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 92081 | Baicalein analytical standard | 491-67-8 | 50MG | ₹12264.73 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 465119 | Baicalein 98% | 491-67-8 | 500MG | ₹9147.13 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 196322 | Baicalein - CAS 491-67-8 - Calbiochem A cell-permeable flavone that inhibits the activity of 12-lipoxygenase (IC??= 120 nM) and reverse transcriptase. | 491-67-8 | 10MG | ₹14260 | 2022-06-14 | Buy |
TCI Chemicals (India) | T2721 | Baicalein | 491-67-8 | 1G | ₹8600 | 2022-05-26 | Buy |
Baicalein Chemical Properties,Uses,Production
Chemical Properties
Yellow Crystalline Solid
Uses
An inhibitor of 12-lipoxygenase, leukotriene biosynthesis and release of lysosomal enzymes. It also inhibits cellular Ca2+ uptake and mobilization and adjuvant-induced arthritis. Baicalein is the fl avonoid component of Nepalese and Sino-Japanese crude drugs.
Definition
ChEBI: A trihydroxyflavone with the hydroxy groups at positions C-5, -6 and -7.
General Description
Baicalein, a flavonoid, is a xanthine oxidase inhibitor. Anti-inflammatory effects of baicalein in peripheral human leukocytes has been studied.
Biological Activity
Inhibitor of 5- and platelet 12-lipoxygenases (IC 50 values are 9.5 and 0.12 mM respectively). Also inhibits Raf-mediated MEK-1 phosphorylation in C6 rat glioma cells and induces G1 and G2 cell cycle arrest by decreasing cdk1, cdk2, cyclin D2 and cyclin A expression. Anti-inflammatory in vivo .
Baicalein Preparation Products And Raw materials
Raw materials
1of2
chevron_rightPreparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
Hebei Duling International Trade Co. LTD | +8617333973358 | China | 15440 | 58 | Inquiry |
Wuhan Haorong Biotechnology Co.,ltd | +86-18565342920; +8618565342920 | China | 293 | 58 | Inquiry |
BINBO BIOLOGICAL CO.,LTD | +8618629063126 | China | 346 | 58 | Inquiry |
Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | China | 3002 | 58 | Inquiry |
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