Emodin
![Emodin Structure](CAS/GIF/518-82-1.gif)
- CAS No.
- 518-82-1
- Chemical Name:
- Emodin
- Synonyms
- RHUBARB EXTRACT;EMODOL;EMODINE;1,3,8-TRIHYDROXY-6-METHYL-9-10-ANTHRACENEDIONE;Ecdyson;1,6,8-Trihydroxy-3-Methylanthraquinone;Emdin;EMODIN;Archin;EMODIN 99
- CBNumber:
- CB2258856
- Molecular Formula:
- C15H10O5
- Molecular Weight:
- 270.24
- MOL File:
- 518-82-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/26 15:15:06
Melting point | 255 °C (dec.)(lit.) |
---|---|
Boiling point | 373.35°C (rough estimate) |
Density | 1.3280 (rough estimate) |
refractive index | 1.5000 (estimate) |
storage temp. | 2-8°C |
solubility | DMSO: soluble |
form | powder |
pka | 6.39±0.20(Predicted) |
color | orange |
Water Solubility | <0.1 g/100 mL at 19 ºC |
Merck | 14,3561 |
BRN | 1888141 |
InChIKey | RHMXXJGYXNZAPX-UHFFFAOYSA-N |
LogP | 3.641 (est) |
CAS DataBase Reference | 518-82-1(CAS DataBase Reference) |
EPA Substance Registry System | Emodin (518-82-1) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302 | |||||||||
Precautionary statements | P264-P270-P301+P312+P330-P501 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36-37/39-36/37 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | CB7920600 | |||||||||
F | 8-10-23 | |||||||||
HS Code | 29146990 | |||||||||
NFPA 704 |
|
Emodin price More Price(17)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | E7881 | Emodin from Frangula bark, ≥90% (HPLC) | 518-82-1 | 50MG | ₹12773.5 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | E7881 | Emodin from Frangula bark, ≥90% (HPLC) | 518-82-1 | 250MG | ₹41254.08 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 324694 | Emodin - CAS 518-82-1 - Calbiochem A cell-permeable, reversible, substrate competitive and potent p56lck tyrosine kinase inhibitor (IC?? = 18.5 μM). | 518-82-1 | 50MG | ₹11880.01 | 2022-06-14 | Buy |
Sigma-Aldrich | 30269 | Emodin analytical standard | 518-82-1 | 10MG | ₹30104.33 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 30269 | Emodin analytical standard | 518-82-1 | 10MG | ₹30104.33 | 2022-06-14 | Buy |
Emodin Chemical Properties,Uses,Production
Chemical Properties
red-orange powder
Uses
Emodin has been used:
- to investigate its regulatory mechanisms on lipopolysaccharide (LPS)-induced inflammatory injury in myocarditis
- as a reference standard for the development and validation of high performance liquid chromatography (HPLC)-photodiode array (PDA) assay method
- to inhibit Tau aggregation
- for direct binding assay
General Description
Orange needles or powder.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Emodin may be sensitive to prolonged exposure to light. Probably a weak acid due to the phenolic functional groups.
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition Emodin emits acrid smoke and irritating fumes.
Fire Hazard
Flash point data for Emodin are not available; however, Emodin is probably combustible.
Biological Activity
Naturally occurring anthraquinone that displays a range of biological activities. Exhibits anti-inflammatory, antitumor and neuroprotective effects.
Purification Methods
Archin forms orange needles from EtOH, Et2O, *C6H6, toluene or pyridine. It sublimes above 200o at 12mm. [Tutin & Clewer J Chem Soc 99 946 1911, IR: Bloom et al. J Chem Soc 178 1959, UV: Birkinshaw Biochem J 59 495 1955, Raistrick Biochem J 34 159 1940.] 1R,2S-(-)Ephedrine see (-)-ephedrine (1R,2S-2-methylamino-1-phenylpropanol) in “Miscellaneous” in Chapter 6.
Emodin Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Avra Synthesis Pvt Ltd | +914027175796 | New Delhi, India | 1606 | 30 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
Natucare India | 08048372644Ext 102 | Mumbai, India | 8 | 58 | Inquiry |
Supplier | Advantage |
---|---|
Avra Synthesis Pvt Ltd | 30 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
A.J Chemicals | 58 |
CLEARSYNTH LABS LTD. | 58 |
Pharmaffiliates Analytics and Synthetics P. Ltd | 58 |
Triveni chemicals | 58 |
SynZeal Research Pvt Ltd | 58 |
Otto Chemie Pvt. Ltd. | 58 |
Alfa Aesar | 58 |
Natucare India | 58 |
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