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Scutellarin

CAS No.: 27740-01-8

Chemical Name:: Scutellarin

Synonyms: SCUTELLARIN;Scutellarin B;Scutellarin ,98%;Erigeron extract;Scutellarin Powder;Scutellarin USP/EP/BP;Scutellarin 27740-01-8;Scutellarin (6CI, 7CI);SCUTELLARIN, 98+% BY HPLC;Scutellarein 7-glucuronide

CBNumber:: CB9117918

Molecular Formula:: C21H18O12

Molecular Weight:: 462.36

MOL File:: 27740-01-8.mol

Modify Date:: 2024/7/2 8:55:39

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Scutellarin Properties

Melting point	300～301℃
Boiling point	891.6±65.0 °C(Predicted)
Density	1.810±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
solubility	DMSO (Slightly), Methanol (Very Slightly, Sonicated)
pka	2.72±0.70(Predicted)
form	Solid
color	Light Yellow to Yellow
BRN	71779
CAS DataBase Reference	27740-01-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Safety Statements	24/25
WGK Germany	3
HS Code	29389090

Scutellarin price More Price(1)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	73577	Scutellarin analytical standard	27740-01-8	10MG	₹34899.8	2022-06-14	Buy

Product number	Packaging	Price	Buy
73577	10MG	₹34899.8	Buy

Scutellarin Chemical Properties,Uses,Production

Description

Scutellarin is a flavone that has been found in S. barbata and has diverse biological activities, including anticancer, lipid lowering, antioxidative, and neurocognitive properties. It inhibits proliferation of PC-9 and H1975 non-small cell lung cancer (NSCLC) cells in a concentration-dependent manner and induces apoptosis and autophagy when used at a concentration of 160 μM, effects that can be blocked by the autophagy inhibitor HCQ . Scutellarin (30 and 60 mg/kg per day) reduces tumor growth in an H1975 mouse xenograft model. It decreases serum total cholesterol and LDL-cholesterol and increases HDL-cholesterol in a high-fat diet-induced mouse model of non-alcoholic fatty liver disease (NAFLD) when administered at doses of 25 and 50 mg/kg. It decreases hepatic malondialdehyde (MDA), glutamic-oxalacetic transaminase (GOT), and glutamic-pyruvic transaminase (GPT) activity, increases catalase (CAT) and total antioxidative capacity (T-AOC) activity, and increases the hepatic expression of PPARγ, PGC-1α, and Nrf2 in the same model. Scutellarin (5, 25, and 50 mg/kg per day) also prevents deficits in spatial and novel object memory in rats in the Y maze and novel object recognition test, respectively.

Definition

ChEBI: The glycosyloxyflavone which is the 7-O-glucuronide of scutellarein.

Scutellarin Preparation Products And Raw materials

Raw materials

4',5,6,7-Tetrahydroxyflavone tetraacetate (2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic SCUTELLAREIN scutellarin Methylester

Preparation Products

cirsimaritin SCUTELLAREIN-7-METHYL ETHER

Scutellarin Suppliers

Global( 276)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
CHEMSWORTH	+91-261-2397244	New Delhi, India	6707	30	Inquiry
Hebei Zhuanglai Chemical Trading Co.,Ltd	+8613343047651	China	3002	58	Inquiry
Hebei Shengyang Water Conservancy Engineering Co., Ltd.	+8615373025980	China	848	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29901	58	Inquiry
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	China	3424	58	Inquiry
BOC Sciences	+1-631-485-4226	United States	19553	58	Inquiry
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	China	39916	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49391	58	Inquiry

Supplier	Advantage
A.J Chemicals	58
CLEARSYNTH LABS LTD.	58
CHEMSWORTH	30
Hebei Zhuanglai Chemical Trading Co.,Ltd	58
Hebei Shengyang Water Conservancy Engineering Co., Ltd.	58
career henan chemical co	58
Chengdu Biopurify Phytochemicals Ltd.	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58

Scutellarin Spectrum

Scutellarin(27740-01-8)¹HNMR

27740-01-8(Scutellarin)Related Search:

Baicalin Baicalein SCUTELLAREIN Isoimperatorin Genistin

Isoliquiritigenin 5,7-Dihydrox -4'-methoxyisoflavone FLAVONE APIGENIN-7-GLUCURONIDE Wogonoside

Tetramethyl-O-scutellarin BAICALIN HYDRATE 3',5'-Dimethoxytricetin 7-O-β-D-glucopypranoside 7-HYDROXYFLAVONE-BETA-D-GLUCOSIDE BREVISCAPIN

Scutellarin ERIGERON BREVISCAPUS SCUTELLARIN:>5%,DCQ:>5%

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SCUTELLARIN, 98+% BY HPLC (4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl β-D-Glucopyranosiduronicacid,5,6-dihydroxy-2- 4',5,6-Trihydroxy-7-[(β-D-glucopyranuronosyl)oxy]flavone 4',5,6-Trihydroxyflavon-7-yl β-D-glucopyranosiduronic acid 5,6-Dihydroxy-4-oxo-2-(4-hydroxyphenyl)-4H-1-benzopyran-7-yl β-D-glucopyranosiduronic acid Scutellarein 4'-methyl ether 7-glucuronide Scutellarein 7-glucuronide SCUTELLARIN SCUTELLAREIN 7-O-GLUCURONIDE Scutellarin ,98% Scutellarin B 7-(beta-d-glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4h-1-benzopyran-4-one 4',5,6,7-Tetrahydroxyflavone 7-β-D-Glucopyranuronoside 5,6-Dihydroxy-2-(p-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl β-D-Glucopyranosiduronic Acid Scutellarein 7-O-β-D-Glucuronide Scutellarein 7-β-D-Glucuronoside Scutellarein 7-b-D-glucuronide Scutellarin 7-(beta-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one 5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-β-D-glucopyranosiduronic acid 7-(β-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one Scutellarin 27740-01-8 Erigeron extract β-D-Glucopyranosiduronic acid, 5,6-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl Scutellarin USP/EP/BP (2S,3S,4S,5R,6S)-6-((5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid Reference Substance Scutellarin (6CI, 7CI) Scutellarin Powder 27740-01-8 Miscellaneous Natural Products chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Inhibitors