ChemicalBook > Product Catalog >Natural Products >Flavonoids >5,7-Dihydrox -4'-methoxyisoflavone

5,7-Dihydrox -4'-methoxyisoflavone

CAS No.: 491-80-5

Chemical Name:: 5,7-Dihydrox -4'-methoxyisoflavone

Synonyms: BIOCHANIN A;BIOCHANIN;BIOCHANIN A (AHP);OlMelin;Pratensol;Bilchanin A;Biochani,Olmelin;5,7-dihydroxy-3-(4-methoxyphenyl)chromen-4-one;5,7-Dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one;NSC 123538

CBNumber:: CB8474490

Molecular Formula:: C16H12O5

Molecular Weight:: 284.26

MOL File:: 491-80-5.mol

MSDS File:: SDS

Modify Date:: 2024/7/8 20:25:11

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5,7-Dihydrox -4'-methoxyisoflavone Properties

Melting point	210-213 °C(lit.)
Boiling point	340-355 °C(Press: 0.5 Torr)
Density	1.420±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	acetone: 10 mg/mL, clear, brown
pka	6.50±0.20(Predicted)
form	Powder
color	Off-White to Beige
Water Solubility	Soluble in water (<1 mg/ml at 25°C), chloroform, methanol, DMSO (57 mg/ml at 25°C), and ethanol (9 mg/ml at 25°C).
λmax	263nm(EtOH)(lit.)
BRN	278107
LogP	3.341 (est)
CAS DataBase Reference	491-80-5(CAS DataBase Reference)
EPA Substance Registry System	4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-methoxyphenyl)- (491-80-5)

SAFETY

Risk and Safety Statements

Safety Statements

22-24/25

WGK Germany

RTECS

DJ3002500

TSCA

Yes

HS Code

29329990

NFPA 704

	1
0		0

5,7-Dihydrox -4'-methoxyisoflavone price More Price(10)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	D2016	Biochanin A	491-80-5	100MG	₹3031	2022-06-14	Buy
Sigma-Aldrich(India)	D2016	Biochanin A	491-80-5	250MG	₹6246.03	2022-06-14	Buy
Sigma-Aldrich(India)	D2016	Biochanin A	491-80-5	1G	₹15079.23	2022-06-14	Buy
Sigma-Aldrich(India)	92142	Biochanin A analytical standard	491-80-5	50MG	₹14592.1	2022-06-14	Buy
TCI Chemicals (India)	B4098	Biochanin A	491-80-5	200MG	₹4700	2022-05-26	Buy

Product number	Packaging	Price	Buy
D2016	100MG	₹3031	Buy
D2016	250MG	₹6246.03	Buy
D2016	1G	₹15079.23	Buy
92142	50MG	₹14592.1	Buy
B4098	200MG	₹4700	Buy

5,7-Dihydrox -4'-methoxyisoflavone Chemical Properties,Uses,Production

Description

Biochanin A is a natural isoflavone with diverse biological actions, most notably as a phytoestrogen. It can affect hormone levels by inhibiting 5α-reductase and 17β-hydroxysteroid dehydrogenase or altering aromatase (CYP19A1) activity. Also known as 4’-methyl genistein, biochanin A can be metabolized in vivo to genistein , another phytoestrogen with diverse effects. Biochanin A also intersects with signaling through peroxisome proliferator-activated receptors (PPARs), as it activates PPARγ (EC₅₀ = 19 μM) and has also been shown to activate a PPARα promoter. Moreover, it increases the expression of the PPARγ coactivator PGC-1α, promoting mitochondrial biogenesis. Biochanin A also inhibits fatty acid amide hydrolase (IC₅₀ = 2.4 μM) and acts as an agonist of the aryl hydrocarbon receptor (EC₅₀ = 0.25 μM).

Chemical Properties

Off-White Solid

Uses

An isoflavone with anticancer proliferation, differentiation and chemopreventitive properties. Inhibits metabolic activation of benzo[a]pyrene

General Description

Biochanin A (BCA) is synthesized in vitro from phloroglucinol. A series of steps involving Friedel?Crafts reaction results in an intermediate product 1-(2,4,6-trihydroxyphenyl)-2-(4 methoxyphenyl) ethanone, which post cyclization leads to BCA. It is catabolized to isoflavone genistein post ingestion.

5,7-Dihydrox -4'-methoxyisoflavone Preparation Products And Raw materials

Raw materials

1-(2,4,6-Trihydroxyphenyl)-2-(4-methoxyphenyl)ethanone 2,4,6-TRIHYDROXYBENZALDEHYDE 2-Bromo-4'-methoxyacetophenone

Preparation Products

D(+)-Glucose 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-methoxyphenyl)-6-(3-methyl-2-buten-1-yl)-

5,7-Dihydrox -4'-methoxyisoflavone Suppliers

Global( 373)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
chromsynth pvt ltd	+919704220374	Hyderabad, India	244	58	Inquiry
Evans Fine Chem	08048602255	Hyderabad, India	289	58	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
TCI Chemicals (India) Pvt. Ltd.	1800 425 7889	New Delhi, India	6778	58	Inquiry
Alfa Aesar	1 800 209 7001	Maharashtra, India	6913	58	Inquiry
SynZeal Research Pvt Ltd	+1 226-802-2078	Gujarat, India	6522	58	Inquiry
Biosyn Research Chemicals	+91 9346022300/+91 9399339999	Telangana, India	1340	58	Inquiry
Shaanxi Dideu Medichem Co. Ltd	18192627656	China	1318	58	Inquiry
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	China	29798	60	Inquiry

Supplier	Advantage
chromsynth pvt ltd	58
Evans Fine Chem	58
A.J Chemicals	58
CLEARSYNTH LABS LTD.	58
TCI Chemicals (India) Pvt. Ltd.	58
Alfa Aesar	58
SynZeal Research Pvt Ltd	58
Biosyn Research Chemicals	58
Shaanxi Dideu Medichem Co. Ltd	58
Capot Chemical Co.,Ltd.	60

5,7-Dihydrox -4'-methoxyisoflavone Spectrum

5,7-Dihydrox -4'-methoxyisoflavone(491-80-5)MS 5,7-Dihydrox -4'-methoxyisoflavone(491-80-5)¹HNMR 5,7-Dihydrox -4'-methoxyisoflavone(491-80-5)IR1 5,7-Dihydrox -4'-methoxyisoflavone(491-80-5)IR2

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5,7-DIHYDROXY-4''-METHOXYISOFLAVONE, 98% BIOCHANIN A 5,7-Dihydrox -4'-methoxyisoflavone Biochanin A, (5,7-Dihydroxy-4’-methoxyisoflavone) Biochanin A，Genistein 4'-methyl ether，5,7-Dihydrox -4'-methoxyisoflavone 3-(4-Methoxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one 4'-Methylgenistein NSC 123538 Biochanin A (4-Methylgenistein) Biochanin A,5,7-Dihydroxy-4′-methoxyisoflavone, Genistein 4′-methyl ether 5,7-dihydroxy-3-(4-methoxyphenyl)-4h-1-benzopyran-4-on 5,7-dihydroxy-3-(4-methoxyphenyl)-4H-1-Benzopyran-4-one APIGENIN 4-METHYL ETHER 5,7-DIHYDROXY-4'-METHOXYISOFLAVONE 5,7-DIHYDROXY-4-METHOXYISOFLAVONE 5,7-dihydroxy-3-p-methoxyphenyl-4H-chromen-4-one 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-methoxyphenyl)- 5,7-Dihydroxy-4'-methoxyisoflavone Genistein 4'-methyl ether 5,7-Dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one 5,7-Dihydrox -4'-methoxyisoflavone 491-80-5 7-hydroxy-3-(4-methoxyphenyl)-4-oxo-1-benzopyran-5-olate Biochanin A > Genistein Methyl Ether Chickpea bud A 5,7-Dihydroxy-4'-methoxyisoflavone (Biochanin A) TIANFUCHEM--High purity 491-80-5 5,7-Dihydrox -4'-methoxyisoflavone Biochani,Olmelin 5,7-dihydroxy-3-(4-methoxyphenyl)chromen-4-one BIOCHANIN A (AHP) BIOCHANIN 5,7-Dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one Bilchanin A OlMelin Pratensol BIOCHANIN A Genistein 4′-methyl ether Chickpea sproutin A Chickpea A 5,7- Dihydroxy - 4'- methoxy Isoflovone (or) Biochanin-A Chickpea sprout extract Biochanin A 98%min Chickpea dentin A 5,7-Dihydrox -4'-methoxyisoflavone 491-80-5 Chromatography Food & Beverage Standards Food Residue Analysis Analytical Standards Analytical Chromatography Product Catalog BioChemical Cancer Research Anti-proliferative Agents Chemopreventive Agents chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Iso-Flavones Inhibitors