Riboflavin 5'-Monophosphate Sodium Salt
![Riboflavin 5'-Monophosphate Sodium Salt Structure](CAS/GIF/130-40-5.gif)
- CAS No.
- 130-40-5
- Chemical Name:
- Riboflavin 5'-Monophosphate Sodium Salt
- Synonyms
- RIBOFLAVIN SODIUM PHOSPHATE;FLAVIN MONONUCLEOTIDE;RIBOFLAVIN-5-PHOSPHATE;Ribo;RIBOFLAVIN 5'-PHOSPHATE SODIUM;Tenofovir Impurity 155;SODIUM RIBOFLAVIN PHOSPHATE;Vitamin B2 Sodium Phosphate;RIBOFLAVINE SODIUM PHOSPHATE;Riboflavin Phosphate Sodium Salt
- CBNumber:
- CB4472478
- Molecular Formula:
- C17H22N4NaO9P
- Molecular Weight:
- 480.35
- MOL File:
- 130-40-5.mol
- Modify Date:
- 2024/5/30 19:23:35
Melting point | >300°C |
---|---|
alpha | [α]D20 +38~+43° (c=1.5, dil. HCl) (Calculated on dehydrous basis) |
FEMA | 2976 | QUININE HYDROCHLORIDE |
refractive index | 41 ° (C=1.5, 5mol/L HCl) |
storage temp. | 2-8°C |
solubility | H2O: soluble50mg/mL, clear, orange |
form | powder |
color | Yellow to Dark Orange |
optical activity | [α]20/D +37 to +42°, c = 1.5 in 5 M HCl(lit.) |
Water Solubility | almost transparency |
Merck | 14,8201 |
BRN | 4106529 |
Stability | Stable. Incompatible with strong oxidizing agents, reducing agents, bases, calcium, metallic salts. Protect from light, air and moisture. |
LogP | -2.193 (est) |
CAS DataBase Reference | 130-40-5(CAS DataBase Reference) |
EPA Substance Registry System | Riboflavin 5'-(dihydrogen phosphate), monosodium salt (130-40-5) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P271-P280 |
Hazard Codes | Xi |
Risk Statements | 36/38 |
Safety Statements | 22-24/25-37/39-26 |
WGK Germany | 3 |
F | 3-8-10 |
HS Code | 29362300 |
Riboflavin 5'-Monophosphate Sodium Salt price More Price(14)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | F6750 | Riboflavin 5′-monophosphate sodium salt hydrate 73-79% (fluorimetric) | 130-40-5 | 25G | ₹7501.73 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | F6750 | Riboflavin 5′-monophosphate sodium salt hydrate 73-79% (fluorimetric) | 130-40-5 | 5G | ₹7815.65 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | F6750 | Riboflavin 5′-monophosphate sodium salt hydrate 73-79% (fluorimetric) | 130-40-5 | 100G | ₹28642.95 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | F2253 | Riboflavin 5′-monophosphate sodium salt hydrate synthetic, ≥70% (HPLC) | 130-40-5 | 10MG | ₹5022.8 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | F2253 | Riboflavin 5′-monophosphate sodium salt hydrate synthetic, ≥70% (HPLC) | 130-40-5 | 25MG | ₹8833.2 | 2022-06-14 | Buy |
Riboflavin 5'-Monophosphate Sodium Salt Chemical Properties,Uses,Production
Chemical Properties
Riboflavin 5'-Monophosphate Sodium Salt is a yellow toorange-yellow, crystalline hygroscopic powder. It is odorless, and has a slightly bitter taste.
It is soluble in water, and practically insoluble in ethanol(95), in chloroform and in diethyl ether.
It is decomposed on exposure to light.
Uses
One of the bioactive forms of Riboflavin. Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, leafy vegetables. Richest natural source is yeast. Minute amounts present in all plant and animal cells. Vitamin (enzyme cofactor).
Application
Riboflavin 5'-Monophosphate Sodium Salt is a coenzyme that is tightly bound to enzymes catalyzing substrate oxidations and reductions, enable an enormous range of chemical transformations in biosynthetic pathways. Riboflavin 5'-Monophosphate Sodium Salt can be used as:
(1) A stable isotope internal standard for the interpretation of data in specific biological samples.
(2) An effective NAD+ reducing agent.
(3) To study progressive keratitis, corneal ectasia and irregular astigmatism.
Biological Functions
Riboflavin 5'-Phosphate Sodium is the phosphate sodium salt form of riboflavin, a water-soluble and essential micronutrient that is the principal growth-promoting factor in naturally occurring vitamin B complexes. Riboflavin phosphate sodium is converted to 2 coenzymes, flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which are necessary for energy production by aiding in the metabolism of fats, carbohydrates and proteins and are required for red blood cell formation and respiration, antibody production and for regulating human growth and reproduction. Riboflavin phosphate sodium is essential for healthy skin, nails and hair growth.
General Description
Riboflavin 5′-monophosphate is also known as flavin mononucleotide (FMN). FMN is a water-soluble micronutrient. It is enzymatically produced from riboflavin (RF). Riboflavin 5′-monophosphate is one of the constituent of enzyme cofactor flavin-adenine dinucleotide.
IC 50
Cryptosporidium hominis TS-DHFR: IC50 = 55 μM; Dihydrofolate reductase: IC50 = 325 μM (human); Thymidylate synthase: IC50 >500 μM (human); Dihydrofolate reductase: IC50 >500 μM (Toxoplasma gondii)
Purification Methods
Purify FMN by paper chromatography using tert-butanol/water, cutting out the main spot and eluting it with water. It can also be purified by adsorption onto an apo-flavodoxin column, followed by elution and freeze drying. It crystallises from aqueous acidic solution. [Mayhew & Strating Eur J Biochem 59 539 1976, Beilstein 26 III/IV 2555.]
Riboflavin 5'-Monophosphate Sodium Salt Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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THE MOLECULEZ | +91-7506703683 +91-7506703683 | Maharashtra, India | 79 | 58 | Inquiry |
Prachi Pharmaceuticals Pvt Ltd | +919004877711 | Mumbai, India | 36 | 58 | Inquiry |
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Supriya Lifescience Ltd | +91-9820804279 +91-9821266261 | Maharashtra, India | 27 | 58 | Inquiry |
Harman Finochem Ltd | +91-2226528080 +91-2226528080 | Maharashtra, India | 37 | 58 | Inquiry |
Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
SKVNTTR LIFE SCIENCE LLP | +91-9825953518 +91-9825953518 | Gujarat, India | 9 | 58 | Inquiry |
Concept Pharmaceuticals Ltd | +91-2242418888 +91-2242418888 | Maharashtra, India | 19 | 58 | Inquiry |
Danashmand Organic Pvt Ltd | +91-9820502311 | Maharashtra, India | 4 | 58 | Inquiry |
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