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ChemicalBook > Product Catalog >Biochemical Engineering >Amino Acids and Derivatives >Glutamic acid derivatives >Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate

Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate

Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate Structure
CAS No.
112889-02-8
Chemical Name:
Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
Synonyms
diethyl n-[5-methylamino-2-thenoyl]-l-glutamate;Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate USP/EP/BP;(S)-Diethyl 2-(5-(MethylaMino)thiophene-2-carboxaMido)pentanedioate;n-[[5-(methylamino)-2-thienyl]carbonyl]-l-glutamic acid diethyl ester;iethyl(2S)-2-[[5-(methylamino)thiophene-2-carbonyl]amino]pentanedioate;L-Glutamic acid, N-[[5-(methylamino)-2-thienyl]carbonyl]-, 1,5-diethyl ester
CBNumber:
CB0855299
Molecular Formula:
C15H22N2O5S
Molecular Weight:
342.41
MOL File:
112889-02-8.mol
MSDS File:
SDS
Modify Date:
2023/12/26 17:07:23
Request For Quotation

Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate Properties

Boiling point 519.6±50.0 °C(Predicted)
Density 1.231
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 12.89±0.46(Predicted)

Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate Chemical Properties,Uses,Production

Uses

N-[[5-(Methylamino)-2-thienyl]carbonyl]-L-glutamic Acid Diethyl Ester can be used as reactant/reagent for synthetic preparation of Raltitrexed (anticancer agent). An intermediate or impurity in the synthesis of Raltitrexed (R100500). Raltitrexed (R100500) is folate-based inhibitor of thymidylate synthase; rapidly and extensively metabolized to its more potent polyglutamate derivatives. Antineoplastic.

Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate Preparation Products And Raw materials

Raw materials

Preparation Products

Diethyl N-[5-[N-[(3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]-N-methylamino]-2-thenoyl]-L-glutamate

Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate Suppliers

Global( 63)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29888 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49392 58 Inquiry
Shanghai Rochi Pharmaceutical Co.,Ltd. 21-38751876 +8615000076078 China 431 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 24200 58 Inquiry
AFINE CHEMICALS LIMITED +86-0571-85134551 China 15395 58 Inquiry
Baoji Guokang Healthchem co.,ltd +8615604608665 15604608665 CHINA 9427 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52861 58 Inquiry
Supplier Advantage
A.J Chemicals 58
CLEARSYNTH LABS LTD. 58
career henan chemical co 58
Chongqing Chemdad Co., Ltd 58
CONIER CHEM AND PHARMA LIMITED 58
Shanghai Rochi Pharmaceutical Co.,Ltd. 58
Dideu Industries Group Limited 58
AFINE CHEMICALS LIMITED 58
Baoji Guokang Healthchem co.,ltd 58
Dayang Chem (Hangzhou) Co.,Ltd. 58

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n-[[5-(methylamino)-2-thienyl]carbonyl]-l-glutamic acid diethyl ester diethyl n-[5-methylamino-2-thenoyl]-l-glutamate (S)-Diethyl 2-(5-(MethylaMino)thiophene-2-carboxaMido)pentanedioate L-Glutamic acid, N-[[5-(methylamino)-2-thienyl]carbonyl]-, 1,5-diethyl ester iethyl(2S)-2-[[5-(methylamino)thiophene-2-carbonyl]amino]pentanedioate Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate USP/EP/BP 112889-02-8 Raltitrexed