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N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid

N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Structure
CAS No.
103878-83-7
Chemical Name:
N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
Synonyms
TeMpiuM;Ro 19-6327/001;JMFKTFLARGGXCC-UHFFFAOYSA-N;N-(2-Aminoethyl)-5-chlor-2-pyridincarbox;N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid;N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride;2-PyridinecarboxaMide, N-(2-aMinoethyl)-5-chloro-, Monohydrochloride;ichemia,Lazabemide,DOPAC,MAO,radical generation,Ro 19-6327,disease,alzheimer′s,Inhibitor,inhibit,Lazabemide hydrochloride,Monoamine Oxidase,smoking cessation,parkinson
CBNumber:
CB11448718
Molecular Formula:
C8H10ClN3O.HCl
Molecular Weight:
0
MOL File:
103878-83-7.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59
Request For Quotation

N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Properties

Melting point 193-195°
storage temp. Desiccate at RT
solubility Soluble to 100 mM in water and to 100 mM in DMSO
form Powder
pka 8.9(at 25℃)

SAFETY

Risk and Safety Statements

Toxicity LD50 orally in mice: 1000-2000 mg/kg (Imhof, Kyburz, 1986)

N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Chemical Properties,Uses,Production

Uses

Treatment of Alzheimer’s disease.

brand name

Tempium (Hoffmann-LaRoche).

Biological Activity

Selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC 50 values are 0.03 and > 100 μ M for MAO-B and MAO-A respectively). Inhibits monoamine uptake at high concentrations (IC 50 values are 86, 123 and > 500 μ M for noradrenalin, serotonin and dopamine uptake respectively).

N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Preparation Products And Raw materials

Raw materials

Preparation Products

N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Suppliers

Global( 23)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Jilin Chinese Academy of Sciences-yanshen Technology +undefined18143011203 China 42057 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 China 48467 58 Inquiry
Jilin Chinese Academy of Sciences-yanshen Technology 18143011203 China 40857 58 Inquiry
MQ (shanghai) Pharmaceuticals Co., Ltd. 13761635123 China 4997 55 Inquiry
BOC Sciences USA 0 65 Inquiry
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 China 15848 69 Inquiry
Supplier Advantage
Career Henan Chemica Co 58
TargetMol Chemicals Inc. 58
LEAPCHEM CO., LTD. 58
Jilin Chinese Academy of Sciences-yanshen Technology 58
Aladdin Scientific 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 58
Jilin Chinese Academy of Sciences-yanshen Technology 58
MQ (shanghai) Pharmaceuticals Co., Ltd. 55
BOC Sciences 65
3B Pharmachem (Wuhan) International Co.,Ltd. 69

103878-83-7(N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid)Related Search:

Methylamine hydrochloride Cysteamine hydrochloride 1-(5-CHLOROPYRIDIN-2-YL)METHANAMINE METHYLPYRIDIN-2-YLMETHYLAMINE DIHYDROCHLORIDE 5-CHLORO-2-FORMYLPYRIDINE
LAZABEMIDE 5-Chloropyridine-2-carboxamide PYRIDINE-2-CARBOXYLIC ACID (2-AMINO-ETHYL)-AMIDE N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
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N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid 2-PyridinecarboxaMide, N-(2-aMinoethyl)-5-chloro-, Monohydrochloride Ro 19-6327/001 TeMpiuM N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride JMFKTFLARGGXCC-UHFFFAOYSA-N N-(2-Aminoethyl)-5-chlor-2-pyridincarbox ichemia,Lazabemide,DOPAC,MAO,radical generation,Ro 19-6327,disease,alzheimer′s,Inhibitor,inhibit,Lazabemide hydrochloride,Monoamine Oxidase,smoking cessation,parkinson 103878-83-7 C8H10ClN3OHCl Monoamine Oxidase