Evans Blue
- CAS No.
- 314-13-6
- Chemical Name:
- Evans Blue
- Synonyms
- t1824;evablin;CI 23860;C.I.24075;DiazoBlue;blue Evan;Evans Blu;diazobleu;Evens Blue;EVANS BLUE
- CBNumber:
- CB1161546
- Molecular Formula:
- C34H29N6NaO14S4
- Molecular Weight:
- 896.86
- MOL File:
- 314-13-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/3/8 18:54:43
| storage temp. | Store at RT. |
|---|---|
| solubility | DMSO (Slightly), Water (Slightly) |
| Colour Index | 23860 |
| form | Powder/Solid |
| color | Dark Brown |
| Water Solubility | 280 g/L (20 ºC) |
| Merck | 14,3905 |
| Stability | Stable. Incompatible with strong reducing agents, strong oxidizing agents. |
| CAS DataBase Reference | 314-13-6 |
| IARC | 3 (Vol. 8, Sup 7) 1987 |
| EPA Substance Registry System | C.I. Direct Blue 53 (314-13-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H350 | |||||||||
| Precautionary statements | P201-P202-P280-P308+P313-P405-P501 | |||||||||
| Hazard Codes | T,F | |||||||||
| Risk Statements | 45-63-11-61-20/21/22 | |||||||||
| Safety Statements | 53-45-36/37-16-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | QJ6440000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 32129000 | |||||||||
| Toxicity | LD50 intraperitoneal in mouse: 340mg/kg | |||||||||
| NFPA 704 |
|
Evans Blue price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | E2129 | Evans Blue Dye content ≥75?% | 314-13-6 | 10G | ₹3507.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | E2129 | Evans Blue Dye content ≥75?% | 314-13-6 | 50G | ₹13963.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | E2129 | Evans Blue Dye content ≥75?% | 314-13-6 | 100G | ₹23887.2 | 2022-06-14 | Buy |
| TCI Chemicals (India) | E0197 | Evans Blue | 314-13-6 | 25G | ₹5200 | 2022-05-26 | Buy |
| SRL | 46650 | Evans Blue | 314-13-6 | 10Gms | ₹1690 | 2022-05-26 | Buy |
Evans Blue Chemical Properties,Uses,Production
Chemical Properties
Evans Blue is a blue crystal with a green metallic luster. It is very soluble in water, slightly soluble in ethanol, and almost insoluble in benzene, chloroform, and ether. It is soluble in acids and alkalis. It is hygroscopic, inducing moisture. It changes color when the pH is close to 10.
Preparation
3,3′-Dimethylbenzidine double nitriding, in alkaline conditions and 4-Amino-5-hydroxynaphthalene-1,3-disulfonic acid (2 Moore) coupled.
Definition
ChEBI: Evans blue is an organic sodium salt that is the tetrasodium salt of 6,6'-{(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[diazene-2,1-diyl]}bis(4-amino-5-hydroxynaphthalene-1,3-disulfonate). It is sometimes used as a counterstain, especially in fluorescent methods to suppress background autofluorescence. It has a role as a histological dye, a fluorochrome, a teratogenic agent and a sodium channel blocker. It contains an Evans blue(4-).
General Description
Blue crystals with a greenish-bronze luster or a black powder.
Air & Water Reactions
Azo dyes can be explosive when suspended in air at specific concentrations. Soluble in water.
Reactivity Profile
Direct Blue 53 is an azo compound. Azo, diazo, azido compounds can detonate. This applies in particular to organic azides that have been sensitized by the addition of metal salts or strong acids. Toxic gases are formed by mixing materials of this class with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. Flammable gases are formed by mixing materials in this group with alkali metals. Explosive combination can occur with strong oxidizing agents, metal salts, peroxides, and sulfides. Direct Blue 53 can react with strong reducing and oxidizing agents.
Fire Hazard
Flash point data for Direct Blue 53 are unavailable; however, Direct Blue 53 is probably combustible.
Biological Activity
Potent inhibitor of L-glutamate uptake into synaptic vesicles. Also inhibits AMPA and kainate receptor-mediated currents (IC 50 values are 220 and 150 nM respectively). P2X-selective purinoceptor antagonist.
Safety Profile
Poison by intraperitoneal route.Moderately toxic by intravenous route. An experimentalteratogen. Other experimental reproductive effects.Questionable carcinogen with experimental tumorigenicdata. Mutation data reported. When heated todecomposition it
Evans Blue Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Arnish Laborates Pvt Ltd | +91 7208475595 | Maharashtra, India | 187 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| Esjay Chemicals | +919820452929 | Maharashtra, India | 110 | 58 | Inquiry |
| GSP Dyes and Chemicals Pvt.Ltd | +91-22-28144802 +91-2228144802 | Maharashtra, India | 79 | 58 | Inquiry |
| Anubhav Business Corporation | +91-2228014519 +91-2228014999 | Maharashtra, India | 119 | 58 | Inquiry |
| Maas Pharma Chemicals | +91-9958666224 | Delhi, India | 1607 | 58 | Inquiry |
| GSP Dyes and Chemicals Pvt. Ltd (Formely known as GSP ENTERPRISES) | 91-22-28144802 | Maharashtra, India | 54 | 58 | Inquiry |
| Kalash Intermediates | 91-9426001352 | Gujarat, India | 39 | 58 | Inquiry |
| Labkemical | 91-171-6532247 | Haryana, India | 73 | 58 | Inquiry |
| Apex Chemicals | +91 22 66313162 | Mumbai, India | 37 | 58 | Inquiry |
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