Ethisterone
- CAS No.
- 434-03-7
- Chemical Name:
- Ethisterone
- Synonyms
- Progestoral;17A-ETHYNYLTESTOSTERONE;Prone;Pranone;Pregnin;Gestoral;NSC-9565;Prodoxan;Produxan;Prolutol
- CBNumber:
- CB1207877
- Molecular Formula:
- C21H28O2
- Molecular Weight:
- 312.45
- MOL File:
- 434-03-7.mol
- Modify Date:
- 2024/11/21 17:11:28
Melting point | 263-269 °C (lit.) |
---|---|
alpha | D23 +23.8° (dioxane); D25 -32.0° (pyridine) |
Boiling point | 392.36°C (rough estimate) |
Density | 1.0697 (rough estimate) |
refractive index | 33 ° (C=1, Pyridine) |
storage temp. | room temp |
solubility | Soluble to 0.05 mg/mL (0.16 mM) in DMSO |
pka | 13.10±0.60(Predicted) |
form | Solid |
color | Light yellow to yellow |
Water Solubility | soluble in chloroform, DMSO (0.05 mg/ml), acetone (slightly ), ethanol (<1 mg/ml at 25°C), and water (<1 mg/ml at 25°C). |
Merck | 14,3741 |
BRN | 1889895 |
InChIKey | CHNXZKVNWQUJIB-CEGNMAFCSA-N |
CAS DataBase Reference | 434-03-7 |
NIST Chemistry Reference | Ethisterone(434-03-7) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS08,GHS09 |
---|---|
Signal word | Danger |
Hazard statements | H360FD-H410 |
Precautionary statements | P201-P202-P273-P280-P308+P313-P391 |
Hazard Codes | Xn,T |
Risk Statements | 40-48-61 |
Safety Statements | 22-24/25-45-53 |
RIDADR | UN 2811 |
WGK Germany | 3 |
RTECS | TU5570250 |
HS Code | 29372390 |
Ethisterone price More Price(2)
Ethisterone Chemical Properties,Uses,Production
Description
Ethisterone is an orally bioavailable synthetic progestin and a derivative of testosterone (Item Nos. ISO60154 | 15645) that binds to progesterone and androgen receptors (EC50s = 23 and 23.1 nM, respectively, in yeast). Ethisterone (1 μM) downregulates progesterone receptors in MCF-7 cells.
Chemical Properties
Off-White Powder
Uses
Ethisterone has been used as a component in Dulbecco′s modified eagle medium (DMEM) to culture the transfected COS-7 cell for transient transfection assay and?gene transfection assay.
Definition
ChEBI: A 17beta-hydroxy steroid that is testosterone in which the 17beta hydrogen is replaced by an ethynyl group. Ethisterone was the first orally active progestin and is a metabolite of danazol.
General Description
Ethisterone is a?progestogen. It is a danazol derivative.
Ethisterone Preparation Products And Raw materials
Raw materials
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AVIK PHARMACEUTICAL LIMITED | +91-22-67685000 | New Delhi, India | 54 | 58 | Inquiry |
Ralington Pharma. | 91-79-48911722 | Gujarat, India | 311 | 58 | Inquiry |
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