Glycine hydrochloride
- CAS No.
- 6000-43-7
- Chemical Name:
- Glycine hydrochloride
- Synonyms
- GLYCINE HCL;GLYCINE-HCL BUFFER;Gly.HCL;h-gly-oh.hcl;ycine hydrochL;GLYCINE HYDROCHLORIDE;Glycocol hydrochloride;GLYCOCOLL HYDROCHLORIDE;GlycineHydrochloride>Glycinehydrochloride,98%
- CBNumber:
- CB1224948
- Molecular Formula:
- C2H6ClNO2
- Molecular Weight:
- 111.53
- MOL File:
- 6000-43-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/13 17:03:25
| Melting point | 176-180 °C(lit.) |
|---|---|
| Density | 1.457[at 20℃] |
| vapor pressure | 0.003Pa at 20℃ |
| storage temp. | 2-8°C |
| form | Crystalline Powder |
| color | White to almost white |
| Water Solubility | SLIGHTLY SOLUBLE |
| Sensitive | Hygroscopic |
| Merck | 14,4491 |
| BRN | 3909617 |
| LogP | -3.25 at 20℃ |
| CAS DataBase Reference | 6000-43-7(CAS DataBase Reference) |
| EPA Substance Registry System | Glycine, hydrochloride (6000-43-7) |
Glycine hydrochloride price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | G2879 | Glycine hydrochloride ≥99% (HPLC) | 6000-43-7 | 100G | ₹4741.35 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | G2879 | Glycine hydrochloride ≥99% (HPLC) | 6000-43-7 | 500G | ₹12264.73 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | G2879 | Glycine hydrochloride ≥99% (HPLC) | 6000-43-7 | 1KG | ₹16421.53 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 55097 | Glycine hydrochloride solution 100?mM amino acid in 0.1 M HCl, analytical standard | 6000-43-7 | 5ML | ₹4286.7 | 2022-06-14 | Buy |
| TCI Chemicals (India) | G0103 | Glycine Hydrochloride | 6000-43-7 | 25G | ₹7200 | 2022-05-26 | Buy |
Glycine hydrochloride Chemical Properties,Uses,Production
Chemical Properties
white crystals or crystalline powder
Uses
Glycine hydrochloride is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.Glycine Hydrochloride is commonly used in buffer solutions, in electrophoresis, and preparative chromatography.
Definition
Glycine hydrochloride is a non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
Preparation
Glycine hydrochloride can be prepared by the action of hydrochloric acid on hippuric acid,aminoacetonitrile,methyleneaminoacetonitrile, and on ethyl phthaliminoacetate. Aniline has been recommended for its conversion into free glycine. Glycine can also be prepared by the interaction of chloroacetic acid and ammonia; by the hydrolysis of methyleneaminoacetonitrile by successive treatments with barium hydroxide and sulfuric acid; and by the hydrolysis of aminoacetonitrile by means of barium hydroxide. A thorough study has been reported for its preparation in improved yields by the sulfuric acid hydrolysis of aminoacetonitrile, and in satisfactory yields from chloroacetic acid and ammonia. Other methods of preparation include the reduction of cyanoformic esters, a modified Curtius degradation of ethyl cyanoacetate, and the hydrolysis of the neck ligaments of cattle.
synthesis of Glycine hydrochloride
Purification Methods
Crystallise the salt from absolute EtOH or 80% EtOH. Monoglycine hydrochloride has m 176-177o, and diglycine monohydrochloride has m 187o. [Frost J Am Chem Soc 64 1286 1942, Beilstein 4 III 1111, 4 IV 2353.]
Glycine hydrochloride Preparation Products And Raw materials
Raw materials
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| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Paras Intermediates Private Limited | +91-2228202847 +91-9820230660 | Maharashtra, India | 11 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6160 | 58 | Inquiry |
| Paras Intermediates Private Limited | 08048970389 | Gujarat, India | 11 | 58 | Inquiry |
| Paras Intermediates Private Limited (PIPL) | 91-22-28202847 | Maharashtra, India | 8 | 58 | Inquiry |
| Maas Pharma Chemicals | +91-9958666224 | Delhi, India | 1607 | 58 | Inquiry |
| Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | China | 2990 | 58 | Inquiry |
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