ChemicalBook > Product Catalog >API >Antineoplastic agents >Antimetabolites, Antineoplastic >Amsacrine
Amsacrine
- CAS No.
- 51264-14-3
- Chemical Name:
- Amsacrine
- Synonyms
- AMSA;CI-880;m-AMSA;C01553;Amekrin;Amsidyl;Amsakrin;AMSIDINE;Lamasine;SN 11841
- CBNumber:
- CB1236394
- Molecular Formula:
- C21H19N3O3S
- Molecular Weight:
- 393.46
- MOL File:
- 51264-14-3.mol
- Modify Date:
- 2024/7/2 8:55:00
| Melting point | 230-240 °C |
|---|---|
| Boiling point | 563.0±60.0 °C(Predicted) |
| Density | 1.2205 (rough estimate) |
| refractive index | 1.6740 (estimate) |
| storage temp. | 2-8°C(protect from light) |
| solubility | Soluble in DMSO |
| form | Powder |
| pka | 8.55±0.10(Predicted) |
| color | Orange to red |
| CAS DataBase Reference | 51264-14-3 |
| IARC | 2B (Vol. 76) 2000 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H227 |
| Precautionary statements | P501-P210-P264-P280-P302+P352-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313-P403+P235 |
| RIDADR | 3249 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| Toxicity | LD50 in male, female CDF1 mice: 810 mg/m2; 729 mg/m2 orally (Pavkov) |
Amsacrine Chemical Properties,Uses,Production
Description
Amsacrine is a cytostatic reported to be active against adult lymphoblastic leukemia which has failed primary treatment or become resistant. Its clinical use, however, is associated with significant neuro-, gastro- and hepatotoxicity.
Uses
Amsacrine (Amsidyl) is used as an Investigational drug.
Definition
ChEBI: A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
Amsacrine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 108)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21675 | 55 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | China | 34571 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 26114 | 58 | Inquiry |
51264-14-3(Amsacrine)Related Search:
M-AMSA, HCL
M-AMSA HYDROCHLORIDE
N-[4-(Acridin-9-ylamino)-3-(methyloxy)phenyl]methanesulfonamide
Amekrin
Amsakrin
Amsidyl
CI-880
4'-(9-Acridinylamino)methanesulfon-m-anisidide
AMSIDINE
META-AMSA
Amsacrine/Amsacrine hydrochloride
Lamasine
m-AMSA
N-[4-(9-Acridinylamino)-3-methoxyphenyl]methanesulfonamide
Amsacrine
4'-(9-Acridinylamino)-3'-methoxymethanesulfonanilide
C01553
N-[4-(acridin-9-ylmethyl)-3-methoxyphenyl]methanesulfonamide
SN 11841
MethanesulfonaMide,N-[4-(9-acridinylaMino)-3-Methoxyphenyl]-
NSC-156303
NSC-249992：SN-11841
AMSA
N-[4-(Acridin-9-yl)amino-3-methoxyphenyl]methanesulfonamide
NSC-249992
m-AMSA Solution
acridinyl anisidide
AMSA;M-AMSA;CI-880;SN-11841;ACRIDINYL ANISIDIDE
Amsacrine USP/EP/BP
51264-14-3
Cell Signaling and Neuroscience
Cell Biology
BioChemical
Apoptosis and Cell Cycle
DNA Repair Regulators
DNA metabolism
Pharmaceutical material and intermeidates