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ChemicalBook > Product Catalog >Organic Chemistry >Inorganic acid Esters >GABEXATE

GABEXATE

GABEXATE Structure
CAS No.
39492-01-8
Chemical Name:
GABEXATE
Synonyms
GABEXATE;Gabexate USP/EP/BP;GabexateMesylateBase;4-[(6-Guanidinohexanoyl)oxy]benzoic acid ethyl ester;ethyl 4-[6-(diaminomethylideneamino)hexanoyloxy]benzoate;diaminomethylidene-[6-(4-ethoxycarbonylphenoxy)-6-oxohexyl]ammonium;4-[[6-[[Amino(imino)methyl]amino]-1-oxohexyl]oxy]benzoic acid ethyl ester;Benzoic acid, 4-[[6-[(aminoiminomethyl)amino]-1-oxohexyl]oxy]-, ethylester;[N'-[5-(4-ethoxycarbonylphenoxy)carbonylpentyl]carbamimidoyl]azanium methanesulfonate
CBNumber:
CB1258637
Molecular Formula:
C16H23N3O4
Molecular Weight:
321.37
MOL File:
39492-01-8.mol
MSDS File:
SDS
Modify Date:
2023/5/15 10:43:59
Request For Quotation

GABEXATE Properties

Boiling point 472.2±55.0 °C(Predicted)
Density 1.20±0.1 g/cm3(Predicted)
storage temp. Desiccate at RT
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 13.83±0.70(Predicted)
color White

GABEXATE Chemical Properties,Uses,Production

Uses

Gabexate mesylate is used in combination with somatostatin and octreotide in the treatment of severe acute pancreatitis in elderly patients.

Biological Activity

Serine protease inhibitor; inhibits trypsin, plasmin, plasma kallikrein and thrombin (IC 50 values are 9.4, 30, 41 and 110 mM respectively). Antithrombotic in vitro and in vivo . Also inhibits LPS-induced TNF- α production, probably by inhibiting NF- κ B and AP-1 activation.

GABEXATE Preparation Products And Raw materials

Raw materials

Sodium hydroxide Ethyl benzoate Thionyl chloride Pyridine

Preparation Products

GABEXATE Suppliers

Global( 31)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-029-89586680 +86-18192503167 China 9030 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 24507 58 Inquiry
Sinoway Industrial co., ltd. 0592-5800732; +8613806035118 China 990 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6846 58 Inquiry
Energy Chemical 021-58432009 400-005-6266 China 44843 58 Inquiry
Foshan Treasure Biotechnology Co., Ltd 0757-85921206 18520245316 China 12664 58 Inquiry
Supplier Advantage
A.J Chemicals 58
Career Henan Chemica Co 58
Shaanxi Dideu Medichem Co. Ltd 58
Dideu Industries Group Limited 58
Sinoway Industrial co., ltd. 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 58
Amadis Chemical Company Limited 58
Shanghai Hao Zhun Biological Technology Co., Ltd. 58
Energy Chemical 58
Foshan Treasure Biotechnology Co., Ltd 58

39492-01-8(GABEXATE)Related Search:

GABEXATE,GABEXATE MESILATE,GABEXATE MESYLATE,GABEXATE METHANESULFONATE,GABEXATE MONOMETHANESULFONATE,Gabexate Mysylate GABEXATE MESILATE WS/JP P-BUTYRYLOXYBENZALDEHYDE 4-PROPIONYLOXYBENZALDEHYDE METHYL 4-ACETOXYBENZOATE
4-N-BUTOXYBENZOIC ACID GABEXATE METHYL 4-N-BUTOXYBENZOATE 6-GUANIDINOHEXANOIC ACID 4-Acetoxybenzoic acid
METHYL 4-N-PENTYLOXYBENZOATE Methyl 4-hexyloxybenzoate
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GABEXATE GabexateMesylateBase [N'-[5-(4-ethoxycarbonylphenoxy)carbonylpentyl]carbamimidoyl]azanium methanesulfonate 4-[(6-Guanidinohexanoyl)oxy]benzoic acid ethyl ester 4-[[6-[[Amino(imino)methyl]amino]-1-oxohexyl]oxy]benzoic acid ethyl ester diaminomethylidene-[6-(4-ethoxycarbonylphenoxy)-6-oxohexyl]ammonium Benzoic acid, 4-[[6-[(aminoiminomethyl)amino]-1-oxohexyl]oxy]-, ethylester Gabexate USP/EP/BP ethyl 4-[6-(diaminomethylideneamino)hexanoyloxy]benzoate 39492-01-8 Proteinase-activated receptor (PAR)