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(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Structure
CAS No.
1987887-92-2
Chemical Name:
(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
Synonyms
Nintedanib-011;Intedanib Impurity D;Nintedanib Impurity q;Nintedanib Impurity 34;Nintedanib impuritiesD;Nintedanib impurities25;NintedanibN-Methylimpurity;Nintedanib N-Methyl Aniline Analog;(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)meth...;(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylen...
CBNumber:
CB13335038
Molecular Formula:
C24H21N3O3
Molecular Weight:
399.44
MOL File:
1987887-92-2.mol
Modify Date:
2023/4/23 13:52:06
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(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Properties

Melting point 273 - 276°C
Boiling point 641.3±55.0 °C(Predicted)
Density 1.316±0.06 g/cm3(Predicted)
storage temp. Refrigerator, under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
pka 11.16±0.20(Predicted)
form Solid
color Yellow to Orange

(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Chemical Properties,Uses,Production

Uses

(3Z)?-2,?3-Dihydro-?3-?[[[4-?(methylamino)?phenyl]?amino]?phenylmethylene]?-?2-?oxo-?1H-?Indole-?6-?carboxylic Acid Methyl Ester is an impurity of Nintedanib (N478290), an angiokinase inhibitor and is used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.

(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Suppliers

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1987887-92-2((Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate)Related Search:

(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester 1-(2-chloroacetyl)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester Nintedanib Methyl oxindole-5-carboxylate N-(4-aMinophenyl)-2-chloro-N-MethylacetaMide
2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID ETHYL ESTER Methyl 1-acetyl-2-oxoindoline-6-carboxylate
1-Chloro-4-(trimethoxymethyl)benzene METHYL OXINDOLE-7-CARBOXYLATE P-ANISALDEHYDE DIMETHYL ACETAL 1,3-DiMethyl 2-[4-(Methoxycarbonyl)-2-nitrophenyl]propanedioate BIBF 1202
N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide Methyl 4-chloro-3-nitrobenzoate
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Intedanib Impurity D Nintedanib Impurity 34 Nintedanib-011 Nintedanib impurity 10/(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)meth... 1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-(methylamino)phenyl]amino]phenylmethylene]-2-oxo-, methyl ester, (3Z)- Nintedanib Impurity q (3Z)?-2,?3-Dihydro-?3-?[[[4-?(methylamino)?phenyl]?amino]?phenylmethylene]?-?2-?oxo-?1H-?Indole-?6-?carboxylic Acid Methyl Ester (Z)-Methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate (Nintedanib Impurity) (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylen... Nintedanib impurities25 Nintedanib impuritiesD NintedanibN-Methylimpurity Nintedanib N-Methyl Aniline Analog (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate 1987887-92-2