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ChemicalBook > Product Catalog >Organic Chemistry >Amides >Amides >N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide

N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide

N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide Structure
CAS No.
1139453-98-7
Chemical Name:
N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide
Synonyms
Nintedanib-003;Intedanib Impurity 12;Intedanib Impurity 27;Nintedanib Intermediate 1;N,4-Dimethyl-N-(4-nitrophenyl)-1-piperazineacetamide;1-Piperazineacetamide, N,4-dimethyl-N-(4-nitrophenyl)-;N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acet...;N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide;N-Methyl-2-(4-methyl-1-piperazinyl)-N-(4-nitrophenyl)acetamide;N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetami...
CBNumber:
CB12520770
Molecular Formula:
C14H20N4O3
Molecular Weight:
292.33
MOL File:
1139453-98-7.mol
Modify Date:
2023/5/4 15:12:17
Request For Quotation

N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide Properties

Melting point 94 - 96°C
Boiling point 446.9±40.0 °C(Predicted)
Density 1.230
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
pka 7.43±0.10(Predicted)
form Solid
color Pale Yellow to Light Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H319-H315-H335
Precautionary statements  P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362

N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide Chemical Properties,Uses,Production

Uses

N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide is used as a reactant in the synthetic preparation of 6-methoxycarbonyl-substituted indolinones, such as Intedanib (I666650), which is a triple angiokinase inhibitor and antitumor agent.

N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide Preparation Products And Raw materials

Raw materials

2-broMo-N-Methyl-N-(4-nitrophenyl)acetaMide 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE 1-Bromo-4-nitrobenzene 1-Methylpiperazine N-Methyl-4-nitroaniline

Preparation Products

(Z)-methyl 3-((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenylamino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide Suppliers

Global( 107)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
BTC pharm India +918790379245 AndhraPradesh, India 1269 58 Inquiry
ALMELO PRIVATE LIMITED +91-9100991345 +91-8500807769 Telangana, India 114 58 Inquiry
Malladi Drugs AND Pharmaceuticals Limited +91-9004653310 +91-9003056437 Tamil Nadu, India 69 58 Inquiry
Accrete Pharmaceuticals Private Limited +91-9246370012 +91-9246370012 Hyderabad, India 24 58 Inquiry
Aventus Labs +91-7021872517 +91-9324342304 Maharashtra, India 168 58 Inquiry
CHEMAZON LABORATORIES +91 9848551964 Hyderabad, India 1320 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29898 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
Supplier Advantage
BTC pharm India 58
ALMELO PRIVATE LIMITED 58
Malladi Drugs AND Pharmaceuticals Limited 58
Accrete Pharmaceuticals Private Limited 58
Aventus Labs 58
CHEMAZON LABORATORIES 58
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
BOC Sciences 58
Chongqing Chemdad Co., Ltd 58

1139453-98-7(N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide)Related Search:

N-(4-aMinophenyl)-2-chloro-N-MethylacetaMide Methyl 1-acetyl-2-oxoindoline-6-carboxylate N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide Nintedanib Methyl oxindole-5-carboxylate
N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID 1-Chloro-4-(trimethoxymethyl)benzene 1-(2-chloroacetyl)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester BIBF 1202
(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester BIBF-1120 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE 2-broMo-N-Methyl-N-(4-nitrophenyl)acetaMide
N-(4-aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide 1,3-DiMethyl 2-[4-(Methoxycarbonyl)-2-nitrophenyl]propanedioate Nintedanib Ethanesulfonate Salt
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N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide N,4-Dimethyl-N-(4-nitrophenyl)-1-piperazineacetamide Nidanib Impurity 12: N-methyl-2- (4-methylpiperazin-1-yl) -N- (4-nitrophenyl) -acetamide N-Methyl-2-(4-methyl-1-piperazinyl)-N-(4-nitrophenyl)acetamide Nintedanib impurity 2/N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide Nintedanib Intermediate 1 Intedanib Impurity 12 Nintedanib-003 1-Piperazineacetamide, N,4-dimethyl-N-(4-nitrophenyl)- N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acet... N,4-Dimethyl-N-(4-Nitrophenyl)-1-Piperazineacetamide(Under Development) N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetami... Intedanib Impurity 27 1139453-98-7 Intermediate of BIBF-1120 and PKI587