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BIBF 1202

BIBF 1202 Structure
CAS No.
894783-71-2
Chemical Name:
BIBF 1202
Synonyms
CS-1313;BIBF 1202;Nintedanib-1;Nintedanib-010;Intedanib Impurity A;Nintedanib impurity A;Nintedanib impuritiesA;Nintedanib Impurity N1;Nintedanib impurities26;Nintedanib Carboxylic Acid
CBNumber:
CB22705077
Molecular Formula:
C30H31N5O4
Molecular Weight:
525.6
MOL File:
894783-71-2.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:15
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BIBF 1202 Properties

Melting point >216°C (dec.)
Boiling point 759.5±60.0 °C(Predicted)
Density 1.331±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility Aqueous Base (Slightly, Heated)
pka 3.94±0.20(Predicted)
form Solid
color Light Yellow to Yellow

BIBF 1202 Chemical Properties,Uses,Production

Description

BIBF 1202 is an active metabolite of the VEGFR, FGFR, and PDGFR inhibitor BIBF 1120 (nintedanib; ). It is formed from BIBF 1120 by intracellular esterases. BIBF 1202 inhibits VEGFR2 with an IC50 value of 62 nM.

Uses

Nintedanib Carboxylic Acid is a related compound of Intedanib (I666650), an indolinone derivative that inhibits angiokinase and an antitumor agent.

BIBF 1202 Preparation Products And Raw materials

Raw materials

Preparation Products

BIBF 1202 Suppliers

Global( 103)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Nanjing Doge Biomedical Technology Co., Ltd +86-25-58227606 +86-15305155328 China 4128 58 Inquiry
China National Standard Pharmaceutical Corporation Limited +8615391658522 China 11927 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Arizest(Shanghai)Pharmatech Co., Ltd +86-021-60753300 China 220 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
SynZeal Research Pvt Ltd 58
BOC Sciences 58
InvivoChem 58
Nanjing Doge Biomedical Technology Co., Ltd 58
China National Standard Pharmaceutical Corporation Limited 58
LEAPCHEM CO., LTD. 58
Arizest(Shanghai)Pharmatech Co., Ltd 58
Amadis Chemical Company Limited 58

894783-71-2(BIBF 1202)Related Search:

Nintedanib N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID ETHYL ESTER (Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
1-Chloro-4-(trimethoxymethyl)benzene Methyl 4-chloro-3-nitrobenzoate 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE 4'-Amino-N-methylacetanilide Ethanesulfonic acid ethyl ester
(3E)-1-Acetyl-3-(ethoxyphenylmethylene)-2,3-dihydro-2-oxo-1H-indole-6-carboxylic Acid Methyl Ester N-(4-aMinophenyl)-2-chloro-N-MethylacetaMide 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Methyl 1-acetyl-2-oxoindoline-6-carboxylate
Nintedanib Impurity 15 P-ANISALDEHYDE DIMETHYL ACETAL Methyl oxindole-5-carboxylate
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(Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1 -yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylic acid Nintedanib impurity A BIBF 1202 (3Z)-2,3-Dihydro-3-[[[4-[methyl[(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic acid Intedanib Impurity A Nintedanib Carboxylic Acid Nintedanib-010 Nintedanib-1 CS-1313 Nintedanib impurity 9/Nintedanib Carboxylic Acid/(Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1 -yl)acetamido)phenyl)amino)(phenyl) methylene)-2-oxoindoline-6-carboxylic acid 1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-, (3Z)- Nintedanib impurities26 Nintedanib impuritiesA Nintedanib Impurity 6Q: What is Nintedanib Impurity 6 Q: What is the CAS Number of Nintedanib Impurity 6 Q: What is the storage condition of Nintedanib Impurity 6 Q: What are the applications of Nintedanib Impurity 6 NintedanibImpurity6-13C-d3 (3Z)-3-[[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]anilino]-phenyl-methylene]-2-oxo-indoline-6-carboxylic acid Nintedanib Impurity N1 Vascular endothelial growth factor receptor|||BIBF-1202|||Inhibitor 894783-71-2 C30H31N5O4