Bupivacaine hydrochloride
- CAS No.
- 14252-80-3
- Chemical Name:
- Bupivacaine hydrochloride
- Synonyms
- Sensorcaine;ah-2250;Bupivocoine HCl;Bupivacaine HCI;Bupivacaine HCL API;marcainehydrochloride;Bupivacaine HCL (USP);BUPIVACAINE HYDROCHLORIDE;Bupivacaine Hydrochloride, USP;Bupivacaine hydrochloride,>98%
- CBNumber:
- CB1386202
- Molecular Formula:
- C18H28N2O.ClH
- Molecular Weight:
- 324.89
- MOL File:
- 14252-80-3.mol
- Modify Date:
- 2024/6/19 22:55:17
Melting point | 249-2510C |
---|---|
storage temp. | Refrigerator |
solubility | Soluble in water, freely soluble in alcohol. |
form | Solid |
color | White to Off-White |
Stability | Hygroscopic |
InChI | InChI=1S/C18H28N2O.ClH/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3;/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21);1H |
InChIKey | SIEYLFHKZGLBNX-UHFFFAOYSA-N |
SMILES | C1(CCCCN1CCCC)C(=O)NC1C(C)=CC=CC=1C.Cl |
CAS DataBase Reference | 14252-80-3(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS06 |
---|---|
Signal word | Danger |
Hazard statements | H330-H300-H310 |
Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P262-P264-P270-P280-P302+P350-P310-P322-P361-P363-P405-P501 |
Hazard Codes | T+ |
Risk Statements | 26/27/28 |
Safety Statements | 22-36/37/39-45 |
RIDADR | UN 2811 6.1/PG 2 |
WGK Germany | 3 |
RTECS | TK6125000 |
HazardClass | 6.1(b) |
PackingGroup | III |
HS Code | 2933399090 |
Toxicity | LD50 in mice (mg/kg): 7.8 i.v., 82 s.c. (Henn, Brattsand) |
Bupivacaine hydrochloride Chemical Properties,Uses,Production
Chemical Properties
White Solid
Biological Functions
Bupivacaine hydrochloride (Marcaine, Sensorcaine) has particularly long action, and some nerve blocks last more than 24 hours; this is often an advantage for postoperative analgesia. Its use for epidural anesthesia in obstetrics has attracted interest because it can relieve the pain of labor at concentrations as low as 0.125% while permitting some motor activity of abdominal muscles to aid in expelling the fetus. The lower concentration minimizes the possibility of cardiac toxicity. Fetal drug concentrations remain low, and drug-induced neurobehavioral changes are not observed in the newborn. Bupivacaine also is approved for spinal anesthesia and is approximately four times more potent and more toxic than mepivacaine and lidocaine. It can be used with or without epinephrine.
Bupivacaine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Dishman Carbogen Amcis Ltd (Dishman Group) | +91-2717420100 +91-8154017093 | Gujarat, India | 90 | 58 | Inquiry |
Mahendra Chemicals | +91-8511204451 +91-9824019625 | Gujarat, India | 7 | 58 | Inquiry |
Harman Finochem Ltd | +91-2226528080 +91-2226528080 | Maharashtra, India | 37 | 58 | Inquiry |
Triveni Interchem Private Limited | +91-02606618618 +91-7574814001 | Gujarat, India | 42 | 58 | Inquiry |
Rivashaa Agrotech Biopharma Pvt. Ltd. | +91-26463395 +91-7926462688 | Gujarat, India | 1615 | 58 | Inquiry |
Narmada Organics | +91-9601758907 +91-9409133000 | Gujarat, India | 19 | 58 | Inquiry |
Surajlok Chemicals Pvt Ltd (Neon Laboratories Ltd) | +91-2268107000 +91-9987232509 | Maharashtra, India | 30 | 58 | Inquiry |
Sanvin Group of Companies (Pioneer Agro Industries) | +91-2261066638 +91-2261066600 | Maharashtra, India | 27 | 58 | Inquiry |
Myosynth Laboratories Pvt Ltd | +91-8913266227 +91-9885891884 | AndhraPradesh, India | 49 | 58 | Inquiry |
Asence Pharma Pvt Ltd | +91-265228317 +91-265228317 | Gujarat, India | 16 | 58 | Inquiry |
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