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Bupivacaine hydrochloride

Bupivacaine hydrochloride Structure
CAS No.
14252-80-3
Chemical Name:
Bupivacaine hydrochloride
Synonyms
Sensorcaine;ah-2250;Bupivocoine HCl;Bupivacaine HCI;Bupivacaine HCL API;marcainehydrochloride;Bupivacaine HCL (USP);BUPIVACAINE HYDROCHLORIDE;Bupivacaine Hydrochloride, USP;Bupivacaine hydrochloride,>98%
CBNumber:
CB1386202
Molecular Formula:
C18H28N2O.ClH
Molecular Weight:
324.89
MOL File:
14252-80-3.mol
Modify Date:
2024/6/19 22:55:17

Bupivacaine hydrochloride Properties

Melting point 249-2510C
storage temp. Refrigerator
solubility Soluble in water, freely soluble in alcohol.
form Solid
color White to Off-White
Stability Hygroscopic
InChI InChI=1S/C18H28N2O.ClH/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3;/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21);1H
InChIKey SIEYLFHKZGLBNX-UHFFFAOYSA-N
SMILES C1(CCCCN1CCCC)C(=O)NC1C(C)=CC=CC=1C.Cl
CAS DataBase Reference 14252-80-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H330-H300-H310
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P262-P264-P270-P280-P302+P350-P310-P322-P361-P363-P405-P501
Hazard Codes  T+
Risk Statements  26/27/28
Safety Statements  22-36/37/39-45
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
RTECS  TK6125000
HazardClass  6.1(b)
PackingGroup  III
HS Code  2933399090
Toxicity LD50 in mice (mg/kg): 7.8 i.v., 82 s.c. (Henn, Brattsand)

Bupivacaine hydrochloride Chemical Properties,Uses,Production

Chemical Properties

White Solid

Biological Functions

Bupivacaine hydrochloride (Marcaine, Sensorcaine) has particularly long action, and some nerve blocks last more than 24 hours; this is often an advantage for postoperative analgesia. Its use for epidural anesthesia in obstetrics has attracted interest because it can relieve the pain of labor at concentrations as low as 0.125% while permitting some motor activity of abdominal muscles to aid in expelling the fetus. The lower concentration minimizes the possibility of cardiac toxicity. Fetal drug concentrations remain low, and drug-induced neurobehavioral changes are not observed in the newborn. Bupivacaine also is approved for spinal anesthesia and is approximately four times more potent and more toxic than mepivacaine and lidocaine. It can be used with or without epinephrine.

Bupivacaine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 330)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Dishman Carbogen Amcis Ltd (Dishman Group) +91-2717420100 +91-8154017093 Gujarat, India 90 58 Inquiry
Mahendra Chemicals +91-8511204451 +91-9824019625 Gujarat, India 7 58 Inquiry
Harman Finochem Ltd +91-2226528080 +91-2226528080 Maharashtra, India 37 58 Inquiry
Triveni Interchem Private Limited +91-02606618618 +91-7574814001 Gujarat, India 42 58 Inquiry
Rivashaa Agrotech Biopharma Pvt. Ltd. +91-26463395 +91-7926462688 Gujarat, India 1615 58 Inquiry
Narmada Organics +91-9601758907 +91-9409133000 Gujarat, India 19 58 Inquiry
Surajlok Chemicals Pvt Ltd (Neon Laboratories Ltd) +91-2268107000 +91-9987232509 Maharashtra, India 30 58 Inquiry
Sanvin Group of Companies (Pioneer Agro Industries) +91-2261066638 +91-2261066600 Maharashtra, India 27 58 Inquiry
Myosynth Laboratories Pvt Ltd +91-8913266227 +91-9885891884 AndhraPradesh, India 49 58 Inquiry
Asence Pharma Pvt Ltd +91-265228317 +91-265228317 Gujarat, India 16 58 Inquiry

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