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ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Pyridine compound >Pyridine derivatives >1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one Structure
CAS No.
55314-16-4
Chemical Name:
1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one
Synonyms
4G-951;Imatinib Impurity 19;Imatinib Impurity 74;Imatinib EP Impurity A;Imatinib USP Impurity A;Nilotinib??Intermediates?B;Imatinib Related Compound A;Imatinib Dimethylamino Impurity;3-Dimethylamino-1-pyridin-3-yl-pr;3-[3-(Dimethylamino)acryloyl]pyridine
CBNumber:
CB1406106
Molecular Formula:
C10H12N2O
Molecular Weight:
176.22
MOL File:
55314-16-4.mol
Modify Date:
2024/6/18 21:58:05
Request For Quotation

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one Properties

Melting point 86-88
Boiling point 281.4±36.0 °C(Predicted)
Density 1.070±0.06 g/cm3(Predicted)
vapor pressure 0.049Pa at 20℃
storage temp. Inert atmosphere,Room Temperature
solubility Soluble in chloroform and dichloromethane.
form powder to crystal
pka 6.19±0.70(Predicted)
color Light yellow to Brown
InChIKey MZLRFUCMBQWLNV-FNORWQNLSA-N
LogP 0.26 at 20℃ and pH7.2
Surface tension 71.8mN/m at 1.008g/L and 20℃
CAS DataBase Reference 55314-16-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xi,Xn
Risk Statements  22-36/37/38
Safety Statements  26-36/37/39
HazardClass  IRRITANT
HS Code  29333990
NFPA 704
1
2 0

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ALFA India ALF-H54187-03 3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one, 97% 55314-16-4 1g ₹5200 2022-05-26 Buy
Product number Packaging Price Buy
ALF-H54187-03 1g ₹5200 Buy

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one Chemical Properties,Uses,Production

Description

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one can be used in the synthesis of imatinib and nilotinib (AMN107), a compound currently in multiple Phase II/III clinical trials for chronic granulocytic leukaemia. Imatinib, on the other hand, is a cancer growth blocker known as a tyrosine kinase inhibitor (TKI), which is used to treat a wide range of leukaemias, myelodysplastic/myeloproliferative disorders, systemic mastocytosis, eosinophilia syndromes, raised dermal fibrosarcoma and gastrointestinal mesenchymal tumours.

Chemical Properties

Off-White Solid

Solubility in organics

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one is soluble in Chloroform and Dichloromethane.

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one Preparation Products And Raw materials

Raw materials

N,N-Dimethylformamide N,N-Dimethylformamide dimethyl acetal 3-Acetylpyridine

Preparation Products

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one Suppliers

Global( 260)Suppliers
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Urantiis Pharmaceuticals Private Limited +918790703567 AndhraPradesh, India 80 58 Inquiry
Rampex Labs Private Limited +91 9168074433 Telangana, India 71 58 Inquiry
Credas Labs Pvt Ltd +91 9133918031 Hyderabad, India 119 58 Inquiry
Shree Jaya Laboratories Pvt. Ltd. +91-91-40-29881167 +91-9966167167 Hyderabad, India 78 58 Inquiry
Lorven therapeutics Pvt Ltd +91-8884110005 +91-8884110005 Hyderabad, India 110 58 Inquiry
Varanous Labs Pvt Ltd +91-7036248882 +91-7036248882 Hyderabad, India 1541 58 Inquiry
Everest Organics Limited +91-4040028838 +91-9440409996 Hyderabad, India 61 58 Inquiry
Vasoya Industries Pvt Ltd +91-9898083583 +91-9898083583 Gujarat, India 42 58 Inquiry
Riddhesh Pharmachem +91-9106014993 +91-9106014993 Gujarat, India 126 58 Inquiry
ALS INDIA LIFE SCIENCES +91-8977036379 +91-8977036379 Hyderabad, India 1879 58 Inquiry
Supplier Advantage
Urantiis Pharmaceuticals Private Limited 58
Rampex Labs Private Limited 58
Credas Labs Pvt Ltd 58
Shree Jaya Laboratories Pvt. Ltd. 58
Lorven therapeutics Pvt Ltd 58
Varanous Labs Pvt Ltd 58
Everest Organics Limited 58
Vasoya Industries Pvt Ltd 58
Riddhesh Pharmachem 58
ALS INDIA LIFE SCIENCES 58

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2-DiMethylaMino-1-(3-pyridyl)-2-propene-1-one 3-[3-(Dimethylamino)acryloyl]pyridine 2-(Dimethylamino)ethenyl 3-Pyridyl Ketone 3-(Dimethylamino)-1-(3-pyridyl)-2-propen-1-one 3-[3-(Dimethylamino)acryloyl]pyridine (E)-3-DIMETHYLAMINO-1-PYRIDIN-3-YL-PROPENONE 3-diMethylaMino-1-(3-pyridyl)-2-propen-1-one, 3-(N,N-diMethylaMino)-1-(pyridin-3-yl)prop-2-en-1-one, 3-(diMethylaMino)-1-(pyridin-3-yl)prop-2-en-1-one 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one 3-(Dimethylamino)-1-(3-pyridinyl)-2-propen-1-one (2E)-3-(Dimethylamino)-1-(3-pyridinyl)-2-propen-1-one (E)-3-dimethylamino-1-(3-pyridyl)prop-2-en-1-one 3-dimethylamino-1-(3-pyridyl)prop-2-en-1-one 3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one 4G-951 Imatinib Dimethylamino Impurity Imatinib USP Impurity A 3-(DIMETHYLAMINO)-1-(3-PYRIDINYL)-2-PROPEN-1-ONE 1-(3-PYRIDYL)-3-(DIMETHYLAMINO)-2-PROPEN-1-ONE 3-(Dimethylamino)-1-pyridin-3-ylprop-2-en-1-one 2-propen-1-one,3-（dimethylamino）-1-（3-pyridinyl） 3-Dimethylamino-1-(pyridin-3-yl)propenone 1-(3-PYRIDYL)-3-(DIMETHYLAMINO)-2-PROPEN-1-ONE 95% 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one ,97% 2-(DiMethylaMino)vinyl 3-Pyridyl Ketone Imatinib Related Compound A 3-(Dimethylamino)-1-(3-pyridinyl)-2-propene-1-one Imatinib Impurity 19 Imatinib EP Impurity A 2-(Dimethylamino)vinyl3-PyridylKetone> Imatinib Dimethylamino Impurity Certified Reference Standard 2-(Dimethylamino)ethenyl 3-Pyridyl Ketone 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one ISO 9001：2015 REACH Imatinib EP Impurity A (Imatinib Dimethylamino Impurity) Nilotinib??Intermediates?B 1 - (3-pyridyl) - 3 - (dimethylamino) - 2-propene-1-one 3-Dimethylamino-1-pyridin-3-yl-pr Imatinib Dimethylamino ImpurityQ: What is Imatinib Dimethylamino Impurity Q: What is the CAS Number of Imatinib Dimethylamino Impurity Q: What is the storage condition of Imatinib Dimethylamino Impurity Q: What are the applications of Imatinib Dimethylamino Impurity Imatinib Impurity 74 2-(Dimethylamino)vinyl 3-Pyridyl Ketone, ≥ 95.0% 55314-16-4 Intermediate of Imatinib Chemical Amines Amines Bases & Related Reagents Intermediates & Fine Chemicals Nucleotides Pharmaceuticals Heterocycles Intermediates