SB 225002
![SB 225002 Structure](CAS/GIF/182498-32-4.gif)
- CAS No.
- 182498-32-4
- Chemical Name:
- SB 225002
- Synonyms
- SB 225002;SB-225002;SB 225002;SB 225002 USP/EP/BP;SB225002 182498-32-4;SB 225002 - CAS 182498-32-4 - Calbiochem;1-(2-bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea;N-(2-BROMOPHENYL)-N'-(2-HYDROXY-4-NITROPHENYL)UREA;N-(2-HYDROXY-4-NITROPHENYL)-N'-(2-BROMOPHENYL)UREA;Urea, N-(2-bromophenyl)-N'-(2-hydroxy-4-nitrophenyl)-
- CBNumber:
- CB1455331
- Molecular Formula:
- C13H10BrN3O4
- Molecular Weight:
- 352.14
- MOL File:
- 182498-32-4.mol
- Modify Date:
- 2023/7/12 16:39:50
Boiling point | 401.6±45.0 °C(Predicted) |
---|---|
Density | 1.793±0.06 g/cm3(Predicted) |
storage temp. | room temp |
solubility | Soluble to 100mM in DMSO and to 50mM in ethanol |
form | Yellow solid |
pka | 5.29±0.10(Predicted) |
color | white to beige |
Sensitive | Moisture Sensitive |
Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months. |
InChIKey | MQBZVUNNWUIPMK-UHFFFAOYSA-N |
CAS DataBase Reference | 182498-32-4 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26 | |||||||||
WGK Germany | 3 | |||||||||
HS Code | 2921490090 | |||||||||
NFPA 704 |
|
SB 225002 price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SML0716 | SB225002 ≥98% (HPLC) | 182498-32-4 | 5MG | ₹11387.9 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML0716 | SB225002 ≥98% (HPLC) | 182498-32-4 | 25MG | ₹46374.3 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 559405 | SB 225002 - CAS 182498-32-4 - Calbiochem A potent, selective, and competitive antagonist of the G-protein coupled receptor CXCR2 (IL-8RB; IC?? = 22 nM for the inhibition of 12?I-IL-8 binding | 182498-32-4 | 1MG | ₹13710 | 2022-06-14 | Buy |
TCI Chemicals (India) | B6055 | SB 225002 | 182498-32-4 | 10MG | ₹7200 | 2022-05-26 | Buy |
TCI Chemicals (India) | B6055 | SB 225002 | 182498-32-4 | 50MG | ₹22500 | 2022-05-26 | Buy |
SB 225002 Chemical Properties,Uses,Production
Description
CXCR2 (IL-
Uses
SB 225002 is a potent and selective CXCR2 antagonist with the ability to inhibit interleukin IL-8 binding to CXCR2.
Biological Activity
Potent and selective CXCR2 chemokine receptor antagonist (IC 50 = 22 nM) that displays > 150-fold selectivity over CXCR1 receptors. Causes inhibition of IL-8 and GRO α -mediated calcium mobilization in HL60 cells (IC 50 values are 8 and 10 nM respectively). Prevents IL-8-induced neutrophil chemotaxis in vitro and sequestration in vivo . Inhibits HIV replication in lymphocytes and macrophages.
SB 225002 Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
Accela ChemBio Inc. | +1-858-6993322 | United States | 19479 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30250 | 58 | Inquiry |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 24200 | 58 | Inquiry |
InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | China | 9991 | 58 | Inquiry |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | China | 11681 | 58 | Inquiry |
182498-32-4(SB 225002)Related Search:
1of4
chevron_right