Ampiroxicam

- CAS No.
- 99464-64-9
- Chemical Name:
- Ampiroxicam
- Synonyms
- Nasil;Flucam;CP 65703;Ampiroam;AMPIROXICAM;Ampiroxicam(CP 65703);Ampiroxicam USP/EP/BP;Ampiroxicam - Bio-X ?;99464-64-9 Ampiroxicam;AMPICILLINTRIHYDRATEPOWDER
- CBNumber:
- CB1461705
- Molecular Formula:
- C20H21N3O7S
- Molecular Weight:
- 447.46
- MOL File:
- 99464-64-9.mol
- Modify Date:
- 2025/1/27 9:38:02
Melting point | 159-161?C |
---|---|
Density | 1.44±0.1 g/cm3(Predicted) |
storage temp. | Sealed in dry,2-8°C |
solubility | Chloroform (Slightly), Methanol (Slightly) |
form | Solid |
pka | 12.74±0.20(Predicted) |
color | White to Off-White |
CAS DataBase Reference | 99464-64-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302 | |||||||||
Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
Toxicity | LD50 orally in male, female rats: 1798, 747 mg/kg (Iijima) | |||||||||
NFPA 704 |
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Ampiroxicam Chemical Properties,Uses,Production
Description
Ampiroxicam is a once-daily non-steroidal anti-inflammatory drug (NSAID) introduced in Japan. As a non-acidic ether carbonate prodrug of the widely used antiinflammatory agent, piroxicam, ampiroxicam is similar or more potent than piroxicam in suppressing carrageenan edema, ultraviolet erythema, traumatic edema, capillary permeability, acetic acid writhing, yeast algesia and yeast hyperthermia in many animals. Eioavailability studies in man show undetectable plasma levels of ampiroxicam indicating 100% conversion to piroxicam during absorption process. Ampiroxicam has been reported to have fewer side effects on the gastric mucosa than piroxicam.
Chemical Properties
White Solid
Uses
Prodrug of Piroxicam. Anti-inflammatory.
Definition
ChEBI: A benzothiazine that is the 1-[(ethoxycarbonyl)oxy]ethyl ether of piroxicam. A prodrug for piroxicam, it is used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis.
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6739 | 58 | Inquiry |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21628 | 55 | Inquiry |
Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | China | 1803 | 55 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29858 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49732 | 58 | Inquiry |
Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | China | 3270 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 32159 | 58 | Inquiry |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 22854 | 58 | Inquiry |