3,4,5-TRIMETHOXYPHENETHYLAMINE, HYDROCHLORIDE
- CAS No.
- 54-04-6
- Chemical Name:
- 3,4,5-TRIMETHOXYPHENETHYLAMINE, HYDROCHLORIDE
- Synonyms
- TMPEA;3,4,5-Trimethoxyphenethylamine;2-(3,4,5-Trimethoxyphenyl)ethanamine;1-amino-2-(3,4,5-trimethoxyphenyl)-ethan;Mezcalin;Mescline;Mescalin;Mezcline;Mezcaline;3,4,5-trimethoxy-phenethylamin
- CBNumber:
- CB1500855
- Molecular Formula:
- C11H17NO3
- Molecular Weight:
- 211.26
- MOL File:
- 54-04-6.mol
- Modify Date:
- 2023/5/9 9:30:27
| Melting point | 35-36° |
|---|---|
| Boiling point | bp12 180° |
| Density | 1.1240 (rough estimate) |
| refractive index | 1.5718 (estimate) |
| pka | 9.57±0.10(Predicted) |
| CAS DataBase Reference | 54-04-6 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
| Toxicity | LD50 i.p. in rats: 370 mg/kg (Speck) |
3,4,5-TRIMETHOXYPHENETHYLAMINE, HYDROCHLORIDE Chemical Properties,Uses,Production
Description
Mescaline is one of the main active ingredients in the peyote plant, Lophophora williamsii. It is also found in several other cacti including the South American Trichocereus otherwise known as the Peruvian torch species. Mescaline can also be synthesized in the laboratory. It is one of the oldest known hallucinogenic drugs. Ingestion of mescaline via use of the peyote cactus has been used in rituals by North American Indians dating back thousands of years. Ingestion of peyote was also common among the Aztec, Apache, and Pima Indians for religious, ceremonial, and medicinal purposes. Mescaline was isolated from peyote in 1896 by the chemist Hefter and in 1919, the chemical structure was confirmed by Spath. There are many analogs of mescaline with over 250 being prepared and self-tested by the chemist and pharmacologist, Alexander Shulgin (aka Sasha Shulgin). Mescaline became a Schedule I drug and was placed in Controlled Substances Act in 1970. Many of the related chemicals or analogs of mescaline were also placed in Schedule I of the Controlled Substances Act.
Chemical Properties
White Powder
Uses
Psychedelic Alkoloid
Definition
ChEBI: A phenethylamine alkaloid that is phenethylamine substituted at positions 3, 4 and 5 by methoxy groups.
Hazard
Highly toxic by ingestion.
Safety Profile
Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion route. An experimental teratogen. Other experimental reproductive effects. Human systemic effects by intramuscular route: euphoria and hallucinations, dstorted perceptions. A psychotoimetic agent (a drug of abuse). When heated to decomposition it emits toxic fumes of NOx.
Environmental Fate
The primary exposure pathway is oral via ingestion of the chemical powder or salt or via ingestion of peyote ‘ buttons.’ These buttons are the round, fleshy tops of the cactus that are sliced and dried. Multiple buttons of peyote are typically ingested due to the relatively small content (i.e., 40–50 mg) of individual peyote buttons.