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ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Epigenetics >HDAC inhibitors >2-Propenamide, N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-, (2E)-

2-Propenamide, N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-, (2E)-

2-Propenamide, N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-, (2E)- Structure
CAS No.
404951-53-7
Chemical Name:
2-Propenamide, N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-, (2E)-
Synonyms
dacinostat;NVP-LAQ824;LAQ-824;CS-1101;Danosta;Danosat;Danostha;Danoselta;LAQ-824 Danosta;LAQ-824 Danos he
CBNumber:
CB1950386
Molecular Formula:
C22H25N3O3
Molecular Weight:
379.45
MOL File:
404951-53-7.mol
MSDS File:
SDS
Modify Date:
2024/7/2 14:09:54
Request For Quotation

2-Propenamide, N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-, (2E)- Properties

Density 1.290±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility insoluble in H2O; insoluble in EtOH; ≥17.45 mg/mL in DMSO
form solid
pka 8.81±0.23(Predicted)
color Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501
NFPA 704
0
2 0

2-Propenamide, N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-, (2E)- Chemical Properties,Uses,Production

Uses

Dacinostat is an inhibitors of aberrant chromatin accessibility. It is also used in the synthesis of triazole-linked indole and oxindole glycoconjugates as potential anticancer agents that inhibits the proliferation of the growth of cancer cell lines.

2-Propenamide, N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-, (2E)- Preparation Products And Raw materials

Raw materials

Preparation Products

2-Propenamide, N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-, (2E)- Suppliers

Global( 110)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Shaanxi Haibo Biotechnology Co., Ltd +undefined18602966907 China 1000 58 Inquiry
Shanghai Daken Advanced Materials Co.,Ltd +86-371-66670886 China 16923 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd +8618829768577 China 1250 58 Inquiry
Nantong HI-FUTURE Biology Co., Ltd. +undefined18051384581 China 3136 58 Inquiry
Supplier Advantage
A.J Chemicals 58
Shaanxi Haibo Biotechnology Co., Ltd 58
Shanghai Daken Advanced Materials Co.,Ltd 58
ATK CHEMICAL COMPANY LIMITED 60
CONIER CHEM AND PHARMA LIMITED 58
career henan chemical co 58
TargetMol Chemicals Inc. 58
InvivoChem 58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd 58
Nantong HI-FUTURE Biology Co., Ltd. 58

2-Propenamide, N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-, (2E)- Spectrum

2-Propenamide, N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-, (2E)-(404951-53-7)1HNMR

404951-53-7(2-Propenamide, N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-, (2E)-)Related Search:

Dideoxyinosine Panobinostat Tacedinaline JNJ-26481585 Mocetinostat (MGCD0103)
Belinostat (PXD101) CRA-02478 2-Propenamide, N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-, (2E)- cinnamoylhydroxamic acid (DIMETHYLAMINOMETHYL)STYRENE
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2-Propenamide, N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-, (2E)- Dacinostat(NVP-LAQ 824) LAQ-824 LAQ824 (Dacinostat) (E)-3-(4-(((2-(1H-indol-3-yl)ethyl)(2-hydroxyethyl)amino)methyl)phenyl)-N-hydroxyacrylamide (E)-N-hydroxy-3-[4-[[2-hydroxyethyl-[2-(1H-indol-3-yl)ethyl]amino]meth yl]phenyl]prop-2-enamide 3-[4-[N-(2-Hydroxyethyl)-N-[2-(1H-indol-3-yl)ethyl]aminomethyl]phenyl]-2(E)-propenohydroxamic acid LAQ824(NVP-LAQ824,Dacinostat) LAQ824 (NVP-LAQ824) Dacinostat(LAQ824) NVP-LAQ824,Dacinostat Dacinostat (NVP-LAQ824, LAQ824) CS-1101 NVP-LAQ824; LAQ824; LAQ 824; LAQ-824 dacinostat NVP-LAQ824 Danoselta Danosta LAQ-824 Danosta Danosat Danostha LAQ-824 Danos he 404951-53-7 Inhibitors Inhibitor