2-amino-4-phosphonobutyric acid

2-amino-4-phosphonobutyric acid Structure
CAS No.
6323-99-5
Chemical Name:
2-amino-4-phosphonobutyric acid
Synonyms
2-Amino-4-phosphonobutanoic acid;Butanoic acid, 2-amino-4-phosphono-;DL-2-Amino-4-phosphonobutyric Acid, 98.0+ % (HPLC)
CBNumber:
CB21333718
Molecular Formula:
C4H10NO5P
Molecular Weight:
183.1
MOL File:
6323-99-5.mol
Modify Date:
2023/6/30 15:45:59

2-amino-4-phosphonobutyric acid Properties

Melting point 229-231 °C(Solv: ethanol (64-17-5); water (7732-18-5))
Boiling point 491.7±55.0 °C(Predicted)
Density 1.628±0.06 g/cm3(Predicted)
storage temp. Store at RT
solubility Water:9.15(Max Conc. mg/mL);50.0(Max Conc. mM)
form White solid.
pka 2.19±0.10(Predicted)
Water Solubility Soluble to 50 mM in water

2-amino-4-phosphonobutyric acid Chemical Properties,Uses,Production

Description

DL-AP4 is a broad-spectrum glutamatergic antagonist. DL-AP4 (2.5 mM) inhibits electrically stimulated synaptic transmission in rabbit hippocampal slices. It also depresses depolarizations induced by NMDA , L-homocysteate, or kainate in isolated frog spinal cord when used at a concentration of 1 mM. DL-AP4 (0.2 mM) inhibits the accumulation of inositol induced by ibotenate , quisqualate, L-glutamate, and L-aspartate in rat hippocampal slices.

2-amino-4-phosphonobutyric acid Preparation Products And Raw materials

Raw materials

Preparation Products

2-amino-4-phosphonobutyric acid Suppliers

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2-Amino-4-phosphonobutanoic acid DL-2-Amino-4-phosphonobutyric Acid, 98.0+ % (HPLC) Butanoic acid, 2-amino-4-phosphono- 6323-99-5