OLSALAZINE
- CAS No.
- 15722-48-2
- Chemical Name:
- OLSALAZINE
- Synonyms
- azodisal;Ph-CJ-91B;Dipentium;OLSALAZINE;Olsalazine D6;Olsalazine-13C6;Olsalazine 13C12;c.i.mordantyellow5;OLSALAZINE USP/EP/BP;OLSALAZINE 15722-48-2
- CBNumber:
- CB2211118
- Molecular Formula:
- C14H10N2O6
- Molecular Weight:
- 302.24
- MOL File:
- 15722-48-2.mol
- Modify Date:
- 2024/7/2 8:55:03
| Melting point | >300 °C(Solv: acetic acid (64-19-7); water (7732-18-5)) |
|---|---|
| Boiling point | 443.29°C (rough estimate) |
| Density | 1.3578 (rough estimate) |
| refractive index | 1.6500 (estimate) |
| pka | 2.40±0.10(Predicted) |
| form | Solid |
| color | Light yellow to yellow |
| Water Solubility | 11.49ug/L(25 ºC) |
| CAS DataBase Reference | 15722-48-2(CAS DataBase Reference) |
OLSALAZINE Chemical Properties,Uses,Production
Uses
Anti-inflammatory (gastrointestinal).
Definition
ChEBI: An azobenzene that consists of two molecules of 4-aminosalicylic acid joined by an azo linkage. A prodrug for mesalazine, an anti-inflammatory drug, it is used (as the disodium salt) in the treatment of inflammatory bowel disease.
Indications
Olsalazine is approved for maintenance of remission of ulcerative colitis, but a commonly reported side effect is a paradoxical increase in diarrhea. The U. S. Food and Drug Administration (FDA) has approved balsalazide disodium (Colazal) as a treatment of mild to moderately active ulcerative colitis.
Mechanism of action
Olsalazine is approved for maintenance of remission of ulcerative colitis, but a commonly reported side effect is a paradoxical increase in diarrhea. The U. S. Food and Drug Administration (FDA) has approved balsalazide disodium (Colazal) as a treatment of mild to moderately active ulcerative colitis.
OLSALAZINE Preparation Products And Raw materials
Raw materials
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OLSALAZINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Varanous Labs Pvt Ltd | +91-7036248882 +91-7036248882 | Hyderabad, India | 1541 | 58 | Inquiry |
| Nivika Chemo Pharma Pvt Ltd | +91-9824176501 +91-9824176501 | Gujarat, India | 15 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21675 | 55 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | China | 9030 | 58 | Inquiry |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | China | 15395 | 58 | Inquiry |
| Sinoway Industrial co., ltd. | 0592-5800732; +8613806035118 | China | 990 | 58 | Inquiry |
| sgtlifesciences pvt ltd | +8617013299288 | China | 12382 | 58 | Inquiry |
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