4'-Hydroxyphenyl Carvedilol
- CAS No.
- 142227-49-4
- Chemical Name:
- 4'-Hydroxyphenyl Carvedilol
- Synonyms
- (R)-BM 14686;(S)-BM 14686;(S)-BM 140686;(R)-BM 140686;4-Hydroxycarvedilol;Carvedilol Impurity 12;(R)-4-Hydroxycarvedilol;(S)-4-Hydroxycarvedilol;4'-HYDROXYPHENYL CARVEDILOL;Carvedilol 4-Hydroxy Metabolite
- CBNumber:
- CB2214210
- Molecular Formula:
- C24H26N2O5
- Molecular Weight:
- 422.47
- MOL File:
- 142227-49-4.mol
- Modify Date:
- 2023/5/18 11:31:03
| Melting point | 163-165°C |
|---|---|
| Boiling point | 702.0±60.0 °C(Predicted) |
| Density | 1.305±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 9.94±0.20(Predicted) |
| color | White to Light Brown |
4'-Hydroxyphenyl Carvedilol Chemical Properties,Uses,Production
Description
4’-hydroxyphenyl Carvedilol is a metabolite of carvedilol that is a more potent β-adrenergic receptor antagonist than carvedilol but has weaker vasodilatory activity. It is formed through oxidation primarily by the cytochrome P450 (CYP) isoform CYP2D6. 4’-hydroxyphenyl Carvedilol inhibits the formation of DPPH radicals in a cell-free assay.
Chemical Properties
Off-White Solid
Uses
4'-Hydroxyphenyl Carvedilol is an optically active metabolite of Carvedilol which is a multiple-action, neurohormonal antagonist that is used in the treatment of hypertension.
4'-Hydroxyphenyl Carvedilol Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 54)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| China National Standard Pharmaceutical Corporation Limited | +8615391658522 | China | 11927 | 58 | Inquiry |
| TCI (Shanghai) Chemical Trading Co., Ltd. | 021-021-61109150 | China | 31163 | 58 | Inquiry |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | China | 29778 | 58 | Inquiry |
| Shenzhen SUNGENING Bio-Medical Co., Ltd. | 0755-28967200 13631290199 | China | 9592 | 60 | Inquiry |
| Chengdu Novel Biomedical Co., Ltd. | 028-85255396 18302801538 | China | 2286 | 58 | Inquiry |
142227-49-4(4'-Hydroxyphenyl Carvedilol)Related Search:
8-Hydroxy Carvedilol
Carvedilol Bisalkylpyrocatechol IMpurity
4'-HYDROXYPHENYL CARVEDILOL
5'-HYDROXYPHENYL CARVEDILOL
(S)-(-)-5'-HYDROXYPHENYL-CARVEDILOL
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(R)-(+)-4'-HYDROXYPHENYL-CARVEDILOL
(S)-(-)-4'-HYDROXYPHENYL-CARVEDILOL
(R)-4-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-3-methoxyphenol
(R)-4-Hydroxycarvedilol
(R)-BM 140686
(R)-BM 14686
(S)-4-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-3-methoxyphenol
(S)-4-Hydroxycarvedilol
(S)-BM 140686
(S)-BM 14686
4-[2-[[3-(9H-Carbazol-4-yloxy)-2-hydroxypropyl]aMino]ethoxy]-3-Methoxyphenol
Carvedilol 4-Hydroxy Metabolite
Carvedilol metabolite 4-Hydroxyphenyl Carvedilol
4'-HYDROXYPHENYL CARVEDILOL
4-Hydroxyphenyl CarvedilolQ: What is
4-Hydroxyphenyl Carvedilol Q: What is the CAS Number of
4-Hydroxyphenyl Carvedilol Q: What is the storage condition of
4-Hydroxyphenyl Carvedilol Q: What are the applications of
4-Hydroxyphenyl Carvedilol
4’-Hydroxyphenyl Carvedilol (10mM in DMSO)
Phenol, 4-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-3-methoxy-
4-Hydroxycarvedilol
Carvedilol Impurity 12
4-(2-((3-((9H-Carbazol-4-yl)oxy)-2-hydroxypropyl)amino)ethoxy)-3-methoxyphenol (Carvedilol Impurity)
142227-49-4
C24H26N2O5
Metabolite
Aromatics
Heterocycles
Chiral Reagents
Intermediates & Fine Chemicals
Metabolites & Impurities
Pharmaceuticals