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Metoprolol tartrate

Metoprolol tartrate Structure
CAS No.
56392-17-7
Chemical Name:
Metoprolol tartrate
Synonyms
beloc;h93/26;Prelis;Niflam;betaloc;seloken;Metapro;Sipseron;lopresor;Selopral
CBNumber:
CB7436617
Molecular Formula:
2C15H25NO3.C4H6O6
Molecular Weight:
684.82
MOL File:
56392-17-7.mol
Modify Date:
2023/6/30 15:45:59

Metoprolol tartrate Properties

Melting point 120℃
Boiling point 695.37°C (rough estimate)
Density 1.1946 (rough estimate)
refractive index 1.5300 (estimate)
Flash point 9℃
storage temp. 2-8°C
solubility H2O: soluble50mg/mL
form powder
color white to off-white
Water Solubility Soluble in water (>1000 mg/ml), methanol (>500 mg/ml), chloroform (496 mg/ml), ethanol (31 mg/ml at 25°C), and DMSO (100 mg/ml at 25°C).
λmax 223nm(H2O)(lit.)
Merck 14,6151
BCS Class 1
Stability Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference 56392-17-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08,GHS09
Signal word  Warning
Hazard statements  H361d-H411
Precautionary statements  P201-P202-P273-P280-P308+P313-P391
Hazard Codes  F,T
Risk Statements  11-23/24/25-39/23/24/25
Safety Statements  7-16-36/37-45-24/25
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  3
RTECS  UB7450100
HS Code  29225090
Toxicity LD50 in female mice, male rats (mg/kg): 118, ~90 i.v.; 2090, 3090 orally (Bodin)
NFPA 704
0
2 0

Metoprolol tartrate price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) M5391 (±)-Metoprolol (+)-tartrate salt ≥98% (titration), powder 56392-17-7 1G ₹3193.38 2022-06-14 Buy
Sigma-Aldrich(India) PHR1076 Metoprolol Tartrate Pharmaceutical Secondary Standard; Certified Reference Material 56392-17-7 1G ₹8465.15 2022-06-14 Buy
Sigma-Aldrich(India) M5391 (±)-Metoprolol (+)-tartrate salt ≥98% (titration), powder 56392-17-7 5G ₹10327.05 2022-06-14 Buy
Sigma-Aldrich(India) M5391 (±)-Metoprolol (+)-tartrate salt ≥98% (titration), powder 56392-17-7 10G ₹18099.4 2022-06-14 Buy
Sigma-Aldrich(India) M-123 Metoprolol tartrate solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? 56392-17-7 1ML ₹3311.7 2022-06-14 Buy
Product number Packaging Price Buy
M5391 1G ₹3193.38 Buy
PHR1076 1G ₹8465.15 Buy
M5391 5G ₹10327.05 Buy
M5391 10G ₹18099.4 Buy
M-123 1ML ₹3311.7 Buy

Metoprolol tartrate Chemical Properties,Uses,Production

Description

Metoprolol (tartrate) (Item No. 21165) is an analytical reference standard categorized as a β1-adrenergic receptor blocker. This product is intended for use in analytical forensic applications. Metoprolol (succinate) is available as a general research tool .

Chemical Properties

White or almost white, crystalline powder or colourless crystals.

Uses

Metoprolol tartrate is an antagonist of the β1-AR (β1-adrenoceptor). It inhibits spontaneous endothelin-1 production in vitro and displays antihypertensive and antianginal activity in vivo.

General Description

A certified solution standard applicable for use in clinical toxicology or forensic analysis by LC-MS/MS or GC/MS. Metoprolol is used for the treatment of multiple heart conditions including hypertension, angina, and tachycardia. This beta blocker is sold under the trade names Lepressor and Toprol XL?.

Biological Activity

Selective β 1 -adrenoceptor antagonist (K i values are 47, 2960 and 10100 nM for β 1 , β 2 and β 3 adrenoceptors respectively). Inhibits spontaneous endothelin-1 production in vitro and displays antihypertensive and antianginal activity in vivo .

Metoprolol tartrate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 480)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Alembic Pharmaceuticals Limited +91-2652280880 +91-2652280550 Gujarat, India 115 58 Inquiry
Ipca Laboratories Ltd +91-2262105000 +91-2262105000 Maharashtra, India 61 58 Inquiry
CTX Lifesciences Pvt Ltd +91-2612399669 +91-7434851395 Gujarat, India 28 58 Inquiry
Sun Pharmaceutical Industries Ltd +91-2242244224 +91-2243244324 Maharashtra, India 108 58 Inquiry
Kopran Ltd +91-9920289074 +91-9820220525 Maharashtra, India 21 58 Inquiry
Afton Pharma +91-9712000202 +91-9712000202 Gujarat, India 63 58 Inquiry
Ralington Pharma +91-7948911722 +91-9687771722 Gujarat, India 1350 58 Inquiry
Reine Lifescience +91-9820193549 +91-9825138460 Gujarat, India 19 58 Inquiry
Globela Industry Pvt Ltd +91-2616158000 +91-9998199919 Gujarat, India 98 58 Inquiry
Exemed Pharmaceuticals (Oneiro Chemicals Pvt Ltd) +91-9687684674 +91-9099061028 Gujarat, India 30 58 Inquiry

Metoprolol tartrate Spectrum

Metoprolol tar 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol, (2R,3R)-2,3-dihydroxybutanedioate (2:1) Metoprolol tartrate solution 2-Propanol, 1-4-(2-methoxyethyl)phenoxy-3-(1-methylethyl)amino-, (2R,3R)-2,3-dihydroxybutanedioate (2:1) (salt) (±)1-(isopropylamino)-3-[p-(β-methoxyethyl)phenoxy]-2-propanol tartrate salt METOPROLOLTARTRATE,USP METOPROLOE TARTRATE (+-)-1-(Isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]-2-propanol tartrate (+-)-Metoprolol bitartrate 1-(Isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]-2-propanol tartrate 2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, (+-)-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (2:1) (salt) 2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, (2R,3R)-2,3-dihydroxybutanedioate (2:1) (salt) (9CI) 2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (2:1) (salt) CGP 2175E HCTCGP 2175E Vasocardin Lopressor, (±)1-(Isopropylamino)-3-[p-(β-methoxyethyl)phenoxy]-2-propanol (+)-tartrate salt 2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, (2R,3R)-2,3-dihydroxybutanedioate (2:1) Metoproferm (±)1-(Isopropylamino)-3-[p-(beta-methoxyethyl)phenoxy]-2-propanol tartrate (2:1) salt Cerekunart Kokonalin Sipseron Zegumular Metoprolol Tartrate (200 mg) (±)-Metoprolol (+)-tartrate salt,(±)1-(Isopropylamino)-3-[p-(β-methoxyethyl)phenoxy]-2-propanol (+)-tartrate salt, Lopressor (±)-Metoprolol (+)-t (±)1-(Isopropylamino)-3-[p-(β-methoxyethyl)phenoxy]-2-propanol tartrate salt Lopressor Metoprolol tartrate, >=99% 1-(Isopropylamino)-3-(4-(2-methoxyethyl)phenoxy)propan-2-ol hemi((2R,3R)-2,3-dihydroxysuccinate) Metoprolol Tartrat (±)1-(Isopropylamino)-3-[p-(β-methoxyethyl)phenoxy]-2-propanol tartrate salt Lopressor 1-(Isopropylamino)-3-(p-(2-methoxyethyl)phenoxy)-2-propanol (2:1) Dextro-tartrate salt artrate(2:1) beloc betaloc h93/26 lopresor lopressor metoprololhemitartrate metoprololtartrate(2:1) seloken slowlopresor METOPROLOL TARTARIC ACID METOPROLOL TARTRATE (+/-)-METOPROLOL (+)-TARTRATE SALT (+-)-1-(isopropylamino)-3-(p-(2-methoxyethyl)phenoxy)-2-propanolhemi-l-tartr (+-)-1-(isopropylamino)-3-(p-(2-methoxyethyl)phenoxy)-2-propanoltartrate(2: 1-(4-(2-methoxyethyl)phenoxy)-3-((1-methylethyl)amino)-2-propano(+-)-2-propanot 1-(isopropylamino)-3-(p-(2-methoxyethyl)phenoxy)-2-propano(+-)-2-propanotartrate 1-(isopropylamino)-3-(p-(2-methoxyethyl)phenoxy)-2-propanol (2:1) dextro-tartrate salt 1-[ISOPROPYLAMINO]-3-[P-(BETA-METHOXY-ETHYL)PHENOXY]-2-PROPANOL(+)-TARTRATE SALT METOPROLOL TARTRATE CRYSTALLINE POWDER 1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol Hemi (+)-Tartrate Lapressor Prelis rac Metoprolol Hemi (+)-Tartrate Selopral 1-(isopropylaMino)-3-(4-(2-Methoxyethyl)phenoxy)propan-2-ol (2R,3R)-2,3-dihydroxysuccinate