Metoprolol tartrate
![Metoprolol tartrate Structure](CAS/GIF/56392-17-7.gif)
- CAS No.
- 56392-17-7
- Chemical Name:
- Metoprolol tartrate
- Synonyms
- beloc;h93/26;Prelis;Niflam;betaloc;seloken;Metapro;Sipseron;lopresor;Selopral
- CBNumber:
- CB7436617
- Molecular Formula:
- 2C15H25NO3.C4H6O6
- Molecular Weight:
- 684.82
- MOL File:
- 56392-17-7.mol
- Modify Date:
- 2023/6/30 15:45:59
Melting point | 120℃ |
---|---|
Boiling point | 695.37°C (rough estimate) |
Density | 1.1946 (rough estimate) |
refractive index | 1.5300 (estimate) |
Flash point | 9℃ |
storage temp. | 2-8°C |
solubility | H2O: soluble50mg/mL |
form | powder |
color | white to off-white |
Water Solubility | Soluble in water (>1000 mg/ml), methanol (>500 mg/ml), chloroform (496 mg/ml), ethanol (31 mg/ml at 25°C), and DMSO (100 mg/ml at 25°C). |
λmax | 223nm(H2O)(lit.) |
Merck | 14,6151 |
BCS Class | 1 |
Stability | Stable. Incompatible with strong oxidizing agents. |
CAS DataBase Reference | 56392-17-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() GHS08,GHS09 |
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Signal word | Warning | |||||||||
Hazard statements | H361d-H411 | |||||||||
Precautionary statements | P201-P202-P273-P280-P308+P313-P391 | |||||||||
Hazard Codes | F,T | |||||||||
Risk Statements | 11-23/24/25-39/23/24/25 | |||||||||
Safety Statements | 7-16-36/37-45-24/25 | |||||||||
RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | |||||||||
WGK Germany | 3 | |||||||||
RTECS | UB7450100 | |||||||||
HS Code | 29225090 | |||||||||
Toxicity | LD50 in female mice, male rats (mg/kg): 118, ~90 i.v.; 2090, 3090 orally (Bodin) | |||||||||
NFPA 704 |
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Metoprolol tartrate price More Price(6)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | M5391 | (±)-Metoprolol (+)-tartrate salt ≥98% (titration), powder | 56392-17-7 | 1G | ₹3193.38 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR1076 | Metoprolol Tartrate Pharmaceutical Secondary Standard; Certified Reference Material | 56392-17-7 | 1G | ₹8465.15 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | M5391 | (±)-Metoprolol (+)-tartrate salt ≥98% (titration), powder | 56392-17-7 | 5G | ₹10327.05 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | M5391 | (±)-Metoprolol (+)-tartrate salt ≥98% (titration), powder | 56392-17-7 | 10G | ₹18099.4 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | M-123 | Metoprolol tartrate solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? | 56392-17-7 | 1ML | ₹3311.7 | 2022-06-14 | Buy |
Metoprolol tartrate Chemical Properties,Uses,Production
Description
Metoprolol (tartrate) (Item No. 21165) is an analytical reference standard categorized as a β1-adrenergic receptor blocker. This product is intended for use in analytical forensic applications. Metoprolol (succinate) is available as a general research tool .
Chemical Properties
White or almost white, crystalline powder or colourless crystals.
Uses
Metoprolol tartrate is an antagonist of the β1-AR (β1-adrenoceptor). It inhibits spontaneous endothelin-1 production in vitro and displays antihypertensive and antianginal activity in vivo.
General Description
A certified solution standard applicable for use in clinical toxicology or forensic analysis by LC-MS/MS or GC/MS. Metoprolol is used for the treatment of multiple heart conditions including hypertension, angina, and tachycardia. This beta blocker is sold under the trade names Lepressor and Toprol XL?.
Biological Activity
Selective β 1 -adrenoceptor antagonist (K i values are 47, 2960 and 10100 nM for β 1 , β 2 and β 3 adrenoceptors respectively). Inhibits spontaneous endothelin-1 production in vitro and displays antihypertensive and antianginal activity in vivo .
Metoprolol tartrate Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Alembic Pharmaceuticals Limited | +91-2652280880 +91-2652280550 | Gujarat, India | 115 | 58 | Inquiry |
Ipca Laboratories Ltd | +91-2262105000 +91-2262105000 | Maharashtra, India | 61 | 58 | Inquiry |
CTX Lifesciences Pvt Ltd | +91-2612399669 +91-7434851395 | Gujarat, India | 28 | 58 | Inquiry |
Sun Pharmaceutical Industries Ltd | +91-2242244224 +91-2243244324 | Maharashtra, India | 108 | 58 | Inquiry |
Kopran Ltd | +91-9920289074 +91-9820220525 | Maharashtra, India | 21 | 58 | Inquiry |
Afton Pharma | +91-9712000202 +91-9712000202 | Gujarat, India | 63 | 58 | Inquiry |
Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
Reine Lifescience | +91-9820193549 +91-9825138460 | Gujarat, India | 19 | 58 | Inquiry |
Globela Industry Pvt Ltd | +91-2616158000 +91-9998199919 | Gujarat, India | 98 | 58 | Inquiry |
Exemed Pharmaceuticals (Oneiro Chemicals Pvt Ltd) | +91-9687684674 +91-9099061028 | Gujarat, India | 30 | 58 | Inquiry |