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ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >protein tyrosine kinase >Momelotinib

Momelotinib

Momelotinib Structure
CAS No.
1056634-68-4
Chemical Name:
Momelotinib
Synonyms
Orange solid;Momelotinib (CYT387);momelotinib(JAK inhibitor)ORPHAN DRUG;CS-177;LM-1149;CYT 387;GS-0387;CYT 11387;MoMelotinib;CYT387, >=98%
CBNumber:
CB22514570
Molecular Formula:
C23H22N6O2
Molecular Weight:
414.46
MOL File:
1056634-68-4.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:03
Request For Quotation

Momelotinib Properties

Density 1.292
storage temp. Store at -20°C
solubility insoluble in EtOH; insoluble in H2O; ≥20.7 mg/mL in DMSO
pka 10.94±0.46(Predicted)
form Orange powder.
color Light yellow to yellow
CAS DataBase Reference 1056634-68-4

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
NFPA 704
0
2 0

Momelotinib Chemical Properties,Uses,Production

Uses

CYT387 inhibits Janus kinase 1 (JAK1) and Janus kinase (JAK2). These kinases are part of the JAK-STAT pathway and dysregulated functions are involved with hematology, oncology and inflammatory diseases.

Momelotinib Preparation Products And Raw materials

Raw materials

Benzoic acid, 4-[3-(dimethylamino)-1-oxo-2-propen-1-yl]-, methyl ester 4-Morpholinoaniline 4-(2-(4-MorpholinophenylaMino)pyriMidin-4-yl)benzoic acid 4-Ethoxycarbonylphenylboronic acid 4-(2-chloro-4-pyrimidinyl)benzoic acid methyl ester
4-[(2E)-3-(Dimethylamino)-1-oxo-2-propen-1-yl]benzoic acid methyl ester 4-(4-NITROPHENYL)MORPHOLINE N-[4-(Morpholin-4-yl)phenyl]guanidine METHYL 4-ACETYLBENZOATE 4-Acetylbenzoic acid
4-(METHOXYCARBONYL)PHENYLBORONIC ACID Aminoacetonitrile hydrochloride 4-Chloronitrobenzene AMINOACETONITRILE
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Preparation Products

Momelotinib Suppliers

Global( 208)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29901 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 26216 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
Supplier Advantage
A.J Chemicals 58
CLEARSYNTH LABS LTD. 58
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
BOC Sciences 58
Chongqing Chemdad Co., Ltd 58
CONIER CHEM AND PHARMA LIMITED 58
TargetMol Chemicals Inc. 58
Dideu Industries Group Limited 58
Zhejiang J&C Biological Technology Co.,Limited 58

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CYT387, >=98% CYT 11387 CYT 387 N-(Cyanomethyl)-4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]benzamide LM-1149 CYT 387(CYT 11387) N-(cyanoMethyl)-4-(2-(4-Morpholin-4-ylphenylaMino)pyriMidin-4-yl)benzaMide MoMelotinib Benzamide,N-(cyanomethyl)-4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]- CYT387;CYT 387; CYT-387 N-(Cyanomethyl)-4-(2-((4-morpholinophenyl)-amino)pyrimidin-4-yl)benzamide N-(Cyanomethyl)-4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]benzamide CYT 387 CYT387(momelotinib) Momelotinib (LM1149 CYT 11387;CYT387 (CYT 387);MOMELOTINIB GS-0387 CS-177 Momelotinib (CYT387,CYT-387) CYT 11387;CYT387 (CYT 387) CYT387 (CYT 387) Momelotinib USP/EP/BP momelotinib(JAK inhibitor)ORPHAN DRUG Orange solid Momelotinib (CYT387) N-(Cyanomethyl)-4-[2-[(4-morpholinophenyl)amino]-4-pyrimidinyl]benzamide Momelotinib (PF-06651600) Momelotinib free base 1056634-68-4 API Inhibitor Anti-cancer Inhibitors