Olmesartan
- CAS No.
- 144689-24-7
- Chemical Name:
- Olmesartan
- Synonyms
- Olmesartan Acid;CS 088;CS-415;RNH 6270;CS 088-d6;OMSTint-H;Olmesartan;Olmesartan EP Imp A;Olmesartan (RNH-6270;Olmesartan Olmesartan
- CBNumber:
- CB2350011
- Molecular Formula:
- C24H26N6O3
- Molecular Weight:
- 446.5
- MOL File:
- 144689-24-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/30 15:45:59
Melting point | 186-188°C |
---|---|
Boiling point | 738.3±70.0 °C(Predicted) |
Density | 1.33 |
storage temp. | 2-8°C |
solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
pka | 2.39±0.50(Predicted) |
form | powder |
color | white to beige |
Stability | Hygroscopic |
CAS DataBase Reference | 144689-24-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H312-H332 |
Precautionary statements | P280-P302+P352-P312-P322-P363-P501-P261-P271-P304+P340-P312-P264-P270-P301+P312-P330-P501 |
RTECS | NI4014100 |
HS Code | 29339900 |
Olmesartan price More Price(2)
Olmesartan Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
Olmesartan Acid (Olmesartan EP Impurity A) is an angiotensin II receptor antagonist. Used as an anti-hypertensive.
General Description
Olmesartan medoxomil, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl-5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate (Benicar, Olmetec) uses the tetrazolering system as its acidic system, which participates inreceptor binding.When administered to a patient, the drugis rapidly and completely bioactivated by ester hydrolysis ofthe medoxomil during absorption from the gastrointestinaltract. Once the prodrug is converted to the active form, virtuallyno further metabolism occurs. In September 2007, theFood and Drug Administration (FDA) approved its use as acombination product with the calcium channel blocker amlodipinefor the management of hypertension. This combinationproduct is sold under the tradename of Azor.
Olmesartan Preparation Products And Raw materials
Raw materials
Preparation Products
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