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ChemicalBook > Product Catalog >Organic Chemistry >Amides >Acyclic polyamines and their derivatives >N,N-Diisopropylethylamine

N,N-Diisopropylethylamine

N,N-Diisopropylethylamine Structure
CAS No.
7087-68-5
Chemical Name:
N,N-Diisopropylethylamine
Synonyms
DIPEA;DIEA;DIISOPROPYLETHYLAMINE;N-Ethyl-N,N-diisopropylamine;N-Ethyl-N-isopropylpropan-2-aMine;ETHYLDIISOPROPYLAMINE;N-ETHYLDIISOPROPYLAMINE;HUNIGS BASE;DIEA EthyldiisopropylaMine;N,N-DIISOPROPYLETHYLAMINE (DIPEA)
CBNumber:
CB4854144
Molecular Formula:
C8H19N
Molecular Weight:
129.24
MOL File:
7087-68-5.mol
MSDS File:
SDS
Modify Date:
2024/4/17 13:57:11
Request For Quotation

N,N-Diisopropylethylamine Properties

Melting point <-50 °C (lit.)
Boiling point 127 °C (lit.)
Density 0.742 g/mL at 25 °C (lit.)
vapor pressure 31 mmHg ( 37.7 °C)
refractive index n20/D 1.457
Flash point 6 °C
storage temp. Store below +30°C.
solubility miscible
pka 10.98±0.28(Predicted)
form Liquid
Specific Gravity 0.755 (20/4℃)
color APHA: <20
PH 12.3 (H2O, 20℃)(as an emulsion)
explosive limit 0.7-6.3%(V)
Water Solubility miscible
BRN 605301
Stability Volatile
InChIKey JGFZNNIVVJXRND-UHFFFAOYSA-N
LogP -1.8 at 22.5℃
CAS DataBase Reference 7087-68-5(CAS DataBase Reference)
NIST Chemistry Reference (i-C3H7)2(C2H5)N(7087-68-5)
EPA Substance Registry System 2-Propanamine, N-ethyl-N-(1-methylethyl)- (7087-68-5)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS05,GHS06,GHS09
Signal word  Danger
Hazard statements  H225-H302-H318-H331-H335-H411
Precautionary statements  P210-P273-P280-P301+P312-P304+P340+P311-P305+P351+P338
Hazard Codes  C,F,T
Risk Statements  11-22-34-52/53-20/21/22-10-41-37/38-20/22-36/37/38-61
Safety Statements  26-36/37/39-45-61-16-27-60-23-9-53
RIDADR  UN 2734 8/PG 2
WGK Germany  2
F  9-34
Autoignition Temperature 240 °C
Hazard Note  Highly Flammable/Corrosive/Harmful
TSCA  Yes
HazardClass  3
PackingGroup  II
HS Code  29211980
Toxicity LD50 orally in Rabbit: > 200 - 500 mg/kg
NFPA 704
3
3 0

N,N-Diisopropylethylamine price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 8.00894 N-Ethyldiisopropylamine for synthesis 7087-68-5 250ML ₹5500 2022-06-14 Buy
Sigma-Aldrich(India) 8.00894 N-Ethyldiisopropylamine for synthesis 7087-68-5 1L ₹30580 2022-06-14 Buy
Sigma-Aldrich(India) 8.00894 N-Ethyldiisopropylamine for synthesis 7087-68-5 2.5L ₹31890 2022-06-14 Buy
Sigma-Aldrich(India) 8.00894 N-Ethyldiisopropylamine for synthesis 7087-68-5 19KG ₹76950 2022-06-14 Buy
Sigma-Aldrich(India) D125806 N,N-Diisopropylethylamine ReagentPlus?, ≥99% 7087-68-5 100ML ₹4384.13 2022-06-14 Buy
Product number Packaging Price Buy
8.00894 250ML ₹5500 Buy
8.00894 1L ₹30580 Buy
8.00894 2.5L ₹31890 Buy
8.00894 19KG ₹76950 Buy
D125806 100ML ₹4384.13 Buy

N,N-Diisopropylethylamine Chemical Properties,Uses,Production

Chemical Properties

Diisopropylethylamine (DIPEA) is a clear, colorless to light yellow liquid, insoluble in water and easily soluble in acetone and other organic solvents.

Uses

N,N-Diisopropylethylamine is used as a base in organic reactions. Used in the preparation of (-)Gambierol a marine polycyclic ether toxin. It is also used in the synthesis of potent inhibitors of human brain memapsin, a key effector in the progression of Alzheimer’s disease.

Application

N,N-Diisopropylethylamine is an important pesticide and pharmaceutical intermediate, which can be used to synthesize anesthetics and herbicides, and can also be used as a sterically hindered amine to participate in various catalytic reactions.

Preparation

N,N-Diisopropylethylamine is used as a non-nucleophilic base in organic synthesis. It is prepared by the alkylation of diisopropylamine with diethyl sulphate. DIPEA can then be purified through distillation from potassium hydroxide if necessary.

General Description

N-Ethyldiisopropylamine (EDIA) reacts with monoactivated Michael acceptors to afford symmetrical sulfones.

Purification Methods

Distil the amine from ninhydrin, then from KOH [Dryland & Sheppard, J Chem Soc, Faraday Trans 1 125 1986]. It is a strong base and should be stored in the absence of carbon dioxide. [Hünig & Kiessel Chem Ber 91 380, 387 1958, Wotiz et al. J Org Chem 24 1202 1959, Beilstein 4 IV 551.]

N,N-Diisopropylethylamine Preparation Products And Raw materials

Raw materials

Preparation Products

3-Azetidinecarboxylic acid 6-CHLORO-5-NITROPYRIMIDIN-4-AMINE TERT-BUTYL N-(BENZYLOXY)CARBAMATE METHYL 3-((PIPERIDIN-4-YL)METHYL)BENZOATE 3-(N-Boc-aminomethyl)azetidine
2-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER 4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE Faropenem sodium hemipentahydrate 5-AMINO-6-CHLORO-PYRIMIDIN-4-OL 4-ETHYNYLANILINE
4-((1-(TERT-BUTOXYCARBONYL)PIPERIDIN-4-YL)METHYL)BENZOIC ACID 2-Ethylpiperazine 1-Boc-3-Cyanoazetidine METHYL 4-((PIPERIDIN-4-YL)METHYL)BENZOATE PIPERAZINE-1,4-DICARBOXYLIC ACID TERT-BUTYL ESTER METHYL ESTER
3-(5-METHYL-1,2,4-OXADIAZOL-3-YL)BENZALDEHYDE 4-(3-BROMOPHENYL)MORPHOLINE 2-((1-(TERT-BUTOXYCARBONYL)PIPERIDIN-4-YL)METHYL)BENZOIC ACID 5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4(3H)-one 5-Amino-4,6-dichloropyrimidine
BAPTA 1-Boc-3-(Aminomethyl)azetidine 4,6-Dichloro-5-nitropyrimidine 2-(PIPERAZIN-1-YL)-ACETIC ACID N-(2-PHENYLETHYL)-AMIDE 3-Bromo-2-methoxy-propene
METHYL 5-NITRO-2-FUROATE 3-[(4-METHYLPIPERAZIN-1-YL)METHYL]BENZALDEHYDE BAPTA, TETRASODIUM SALT 4-CHLORO-6-HYDRAZINO-PYRIMIDIN-5-YLAMINE 3-((1-(TERT-BUTOXYCARBONYL)PIPERIDIN-4-YL)METHYL)BENZOIC ACID
4,5-Diaminopyrimidine N-(4-FORMYL-PYRIDIN-3-YL)-2,2-DIMETHYL-PROPIONAMIDE (R)-4-Boc-Piperazine-3-carboxylic acid METHYL 2-((PIPERIDIN-4-YL)METHYL)BENZOATE N-Boc-5,6,7,8-tetrahydro-3-methoxy-[1,2,4]triazolo[4,3-A]pyrazine ,98%
1-Boc-Azetidine-3-yl-methanol (11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-DIMETHYLAMINE 4-Methoxybenzyl isocyanate 2-(TRIFLUOROMETHYL)THIAZOLE-5-CARBALDEHYDE 3-HYDROXYMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
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N,N-Diisopropylethylamine Suppliers

Global( 639)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ANJI BIOSCIENCES +91-9000100077 +91-9000100077 Hyderabad, India 430 58 Inquiry
PACIFIC ORGANICS PVT LTD +91 9322467890 Maharashtra, India 51 58 Inquiry
JSK Chemicals +919879767970 Gujarat, India 3756 58 Inquiry
SYNGENESIS CHEMSCIENCE PRIVATE LIMITED +91-9067779401 +91-9067779401 Maharashtra, India 58 58 Inquiry
BASF India Limited +91-2262785600 +91-2262785600 Maharashtra, India 209 58 Inquiry
Manas Petro Chem +91-9004912487 +91-9004912487 Maharashtra, India 17 58 Inquiry
Asmee Chemicals +91-9422076445 +91-9920257026 Maharashtra, India 16 58 Inquiry
Dr. Silviu Pharmachem Pvt., Ltd. +91-8390608382 +91-8390608382 Mumbai, India 248 58 Inquiry
Rivashaa Agrotech Biopharma Pvt. Ltd. +91-26463395 +91-7926462688 Gujarat, India 1615 58 Inquiry
Naarini MolBio Pharma Pvt Ltd +91-7948949309 +91-7948949309 Gujarat, India 32 58 Inquiry
Supplier Advantage
ANJI BIOSCIENCES 58
PACIFIC ORGANICS PVT LTD 58
JSK Chemicals 58
SYNGENESIS CHEMSCIENCE PRIVATE LIMITED 58
BASF India Limited 58
Manas Petro Chem 58
Asmee Chemicals 58
Dr. Silviu Pharmachem Pvt., Ltd. 58
Rivashaa Agrotech Biopharma Pvt. Ltd. 58
Naarini MolBio Pharma Pvt Ltd 58

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  • What is N,N-Diisopropylethylamine?
  • N,N-Diisopropylethylamine is also known as Hunig’s base and abbreviated as DIPEA or DIEA, N,N-Diisopropylethylamine is a steri....
  • Jun 29，2020

N,N-Diisopropylethylamine Spectrum

N,N-Diisopropylethylamine(7087-68-5)MSN,N-Diisopropylethylamine(7087-68-5)1HNMRN,N-Diisopropylethylamine(7087-68-5)13CNMRN,N-Diisopropylethylamine(7087-68-5)IR1N,N-Diisopropylethylamine(7087-68-5)Raman

7087-68-5(N,N-Diisopropylethylamine)Related Search:

Diisopropylamine POLY(N-ISOPROPYL ACRYLAMIDE) N-Isopropylacrylamide Lithium diisopropylamide Diisopropyl ether
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Diisopropanol-p-toluidine N,N-Diethylaniline ACETIC ACID-DIISOPROPYLAMIDE 4-Acetylphenylboronic acid 2-Diisopropylaminoethyl chloride hydrochloride
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N N-DIISOPROPYLETHYLAMINE (ATOFINA ED& N N-DIISOPROPYLETHYLAMINE REAGENTPLUS(& N,N-DIISOPROPYLETHYLAMINE, BIOTECH GRADE SOLVENT, 99.5% N-ETHYLDIISOPROPYLAMINE, 4X25 ML VIALS N,N-Di-#niso-propylethylamine N N-DIISOPROPYLETHYLAMINE BIOTECH GRAD& N N-DIISOPROPYLETHYLAMINE REDISTILLED & N,N-DIISOPROPYLETHYLAMINE, REDISTILLED, 99.5% HUENIG'S BASE 'HUNIG'S BASE' Hunig’sreagent N,N-Diisopropyl-ethylamin DIEA/NMP (2.0M N,N-Diisopropylethylamine, 98+% N,N-Diisopropylethylamine, 99.5+% N,N-Diisopropylethylamine/1-Methyl-2-pyrrolidinone, 2 bottles kit for 2.0M solution, for peptide synt. DIISOPROPYLETHYLAMINE (DIEA) DIEA N,N’-Diisopropyl ethylamine N,N-DIISOPROPYLETHYLAMINE (HUENIGS BASE) Hμnigs base, N-Ethyldiisopropylamine, DIPEA, Ethyldiisopropylamine N,N-Diisopropylethanamine N,N-Diisopropylethylamine/1-Methyl-2-pyrrolidinone,2 bottles kit for 2.0M solution, for pe N,N-Diisopropylethylamine ,99.5% [Moisture content≤300PPM] N-Ethyldiisopropylamine solution,N,N-Diisopropylethylamine, DIPEA, Hünig’s base N-Ethyldiisopropylamine,N,N-Diisopropylethylamine, Hünigs base DIISOPROPYLETHYLAMINE/WATER, PROTEINSEQU ENCING GRA N,N-Diisopropylethyl N-ethyl-N-propan-2-yl-propan-2-amine N,N-DIISOPROPYLETHYLAMINE N-ETHYLDISSOPROPLYAMINE (CH3)2CHN(C2H5)CH(CH3)2 N,N-Diisopropylethylamine, Ethyldiisopropylamine, Hμnigs base N,N-Diisopropylethylamine, Hμnigs base N,N-DiisopropylethylaMine, 98+% 100GR N,N-DiisopropylethylaMine, 98+% 25GR N,N-DiisopropylethylaMine, 98+% 500GR N,N-DiisopropylethylaMine, 99.5+% 100ML N,N-DiisopropylethylaMine, 99.5+% 50ML N-DiisopropylethylaMine (DIPEA) EthyldiisopropylaMine(DIEA EDIA) N-Ethyldiisopropylamine DIPEA Hunig's Base N-Ethyldiisopropylamine BASF quality, >=98.0% MEDIABAG B WITH 375 G SKIMMED MILK N,N-diisopropyethyl amine N,N'-Diisopropylethylamine≥ 99.7% (GC) N-Ethyldiisopropylamin N-Ethyl-N-(1-methylethyl)-2-methylethanamine n-ethyl-n-(1-methylethyl)-2-propanamin N-Ethyl-N-isopropyl-2-propanamine Triethylamine, 1,1'-dimethyl- Triethylamine,1,1’-dimethyl- 1,1’-Dimethyltriethylamine 2-Propanamine, N-ethyl-N-(1-methylethyl)- 2-Propanamine,N-ethyl-N-(1-methylethyl)- Bis(1-methylethyl)ethylamine Hünig’sBase N,N-DIISOPROPYLETHYLAMINE (HONIG''S BASE) DI-DEHYDROCOELENTERAZINE