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Ethyl maltol

Ethyl maltol Structure
CAS No.
4940-11-8
Chemical Name:
Ethyl maltol
Synonyms
2-ETHYL-3-HYDROXY-4H-PYRAN-4-ONE;6-ETHYL-3-HYDROXY-2-METHYL-4H-PYRAN-4-ONE;3-HYDROXY-2-ETHYL-4-PYRONE;FEMA 3487;2-ETHYL-3-HYDROXY-4-PYRONE;veltolplus;ethyl mantol;ETHYL MALTOL;yijimaiyafen;ethyl palatone
CBNumber:
CB6772323
Molecular Formula:
C7H8O3
Molecular Weight:
140.14
MOL File:
4940-11-8.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:14

Ethyl maltol Properties

Melting point 85-95 °C (lit.)
Boiling point 196.62°C (rough estimate)
Density 1.1624 (rough estimate)
vapor pressure 0.2Pa at 24℃
FEMA 3487 | ETHYL MALTOL
refractive index 1.4850 (estimate)
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
pka 8.38±0.10(Predicted)
form Solid
color White to Pale Yellow
Odor at 5.00 % in benzyl alcohol. sweet caramel jam strawberry cotton candy
Odor Type caramellic
Water Solubility 9.345g/L at 24℃
Merck 14,3824
JECFA Number 1481
LogP 2.9 at 25℃
CAS DataBase Reference 4940-11-8(CAS DataBase Reference)
NIST Chemistry Reference 4H-pyran-4-one, 2-ethyl-3-hydroxy-(4940-11-8)
EPA Substance Registry System 4H-Pyran-4-one, 2-ethyl-3-hydroxy- (4940-11-8)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  Xn
Risk Statements  22
Safety Statements  36
WGK Germany  3
RTECS  UQ0840000
HS Code  29329990
Toxicity LD50 orally in male mice, male rats, female rats, chicks (mg/kg): 780, 1150, 1200, 1270 (Gralla)

Ethyl maltol price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) W348708 Ethyl maltol ≥99%, FCC, FG 4940-11-8 1SAMPLE-K ₹5141.88 2022-06-14 Buy
Sigma-Aldrich(India) W348708 Ethyl maltol ≥99%, FCC, FG 4940-11-8 100G ₹6971.3 2022-06-14 Buy
Sigma-Aldrich(India) W348708 Ethyl maltol ≥99%, FCC, FG 4940-11-8 1KG ₹10889.95 2022-06-14 Buy
Sigma-Aldrich(India) W348708 Ethyl maltol ≥99%, FCC, FG 4940-11-8 5KG ₹30136.8 2022-06-14 Buy
Sigma-Aldrich(India) W348708 Ethyl maltol ≥99%, FCC, FG 4940-11-8 25KG ₹110111.9 2022-06-14 Buy
Product number Packaging Price Buy
W348708 1SAMPLE-K ₹5141.88 Buy
W348708 100G ₹6971.3 Buy
W348708 1KG ₹10889.95 Buy
W348708 5KG ₹30136.8 Buy
W348708 25KG ₹110111.9 Buy

Ethyl maltol Chemical Properties,Uses,Production

Chemical Properties

Ethyl maltol has a very sweet, fruit-like odor of immense tenacity and sweet, fruity taste with initial bitter-tart flavor; rapid loss of flavor per se. It is four to six times more potent than maltol.

Occurrence

Has apparently not been reported to occur in nature.

Uses

Ethyl Maltol is a flavoring agent that is a white, crystalline powder. it has a unique odor and a sweet taste that resembles fruit. the melt- ing point is 90°c. it is sparingly soluble in water and propylene gly- col and soluble in alcohol and chloroform. it is obtained by chemical synthesis.

Preparation

Several syntheses have been developed for its preparation. In a one-pot process, for example, ??-ethylfurfuryl alcohol is treated with halogen to give 4-halo- 6-hydroxy-2-ethyl-2H-pyran-3(6H)-one, which need not be isolated and can be converted to ethylmaltol by aqueous hydrolysis.

Production Methods

Unlike maltol, ethyl maltol does not occur naturally. It may be prepared by treating a-ethylfurfuryl alcohol with a halogen to produce 4-halo-6-hydroxy-2-ethyl-2H-pyran-3(6H)-one, which is converted to ethyl maltol by hydrolysis.

General Description

Ethyl maltol is a synthetic homologue of maltol, often found as flavor enhancers and it contributes to the fragrance of commercials products such as cereals, breads, malt beverages, coffee, soybeans and chocolate milk.

Pharmaceutical Applications

Ethyl maltol is used in pharmaceutical formulations and food products as a flavoring agent or flavor enhancer in applications similar to maltol. It has a flavor and odor 4–6 times as intense asmaltol. Ethyl maltol is used in oral syrups at concentrations of about 0.004% w/v and also at low levels in perfumery.

Safety Profile

Moderately toxic by ingestion and subcutaneous routes. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.

Safety

In animal feeding studies, ethyl maltol has been shown to be well tolerated with no adverse toxic, reproductive, or embryogenic effects. It has been reported that while the acute toxicity of ethyl maltol, in animal studies, is slightly greater than maltol, with repeated dosing the opposite is true. The WHO has set an acceptable daily intake for ethyl maltol at up to 2 mg/kg bodyweight.
LD50 (chicken, oral): 1.27 g/kg
LD50 (rat, oral): 1.15 g/kg
LD50 (mouse, oral): 0.78 g/kg
LD50 (mouse, SC): 0.91 g/kg

Metabolism

When orally administered, ethyl maltol was rapidly and extensively absorbed. Elimination was also extensive and rapid, involving conjugation as the glucuronide and ethereal sulphate, and excretion in the urine to the extent of 65-70% within 24 hr. Rate studies after iv dosage indicated that the bulk (86%) of the recovered conjugates was excreted within 6 hr (Rennhard, 1971).

storage

Solutions may be stored in glass or plastic containers. The bulk material should be stored in a well-closed container, protected from light, in a cool, dry place.

Regulatory Status

GRAS listed. Included in the FDA Inactive Ingredients Database (oral syrup).

Global( 484)Suppliers
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SNECOFRi Pvt Ltd +91-9032850129 +91-9032850129 Telangana, India 404 58 Inquiry
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Colorchem Industries Limited 08048983310 Madhya Pradesh, India 22 58 Inquiry
M. P. Aromas 08048958680 Mumbai, India 40 58 Inquiry
M A Aromas 07942553282 Mumbai, India 26 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry

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