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Kojic acid

Kojic acid Structure
CAS No.
501-30-4
Chemical Name:
Kojic acid
Synonyms
kojic;kojic acid powder;KAD;5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE;4H-Pyran-4-one, 5-hydroxy-2-(hydroxymethyl)-;5-Hydroxy-2-(hydroxyMethyl)-4H-pyranone;KJ ACID;NSC 1942;Kojic acid;Kojci Acid
CBNumber:
CB7272507
Molecular Formula:
C6H6O4
Molecular Weight:
142.11
MOL File:
501-30-4.mol
MSDS File:
SDS
Modify Date:
2024/8/1 17:24:36

Kojic acid Properties

Melting point 152-155 °C (lit.)
Boiling point 179.65°C (rough estimate)
Density 1.1712 (rough estimate)
refractive index 1.4434 (estimate)
storage temp. Store below +30°C.
solubility DMSO (Slightly), Methanol (Slightly, Sonicated)
form Crystalline Powder
pka 7.9(at 25℃)
color White to beige-brown
Water Solubility SOLUBLE
λmax 269nm(CHCl3)(lit.)
Merck 14,5317
BRN 120895
Stability Stable. Combustible. Incompatible with strong oxidizing agents.
LogP -0.640
CAS DataBase Reference 501-30-4(CAS DataBase Reference)
NIST Chemistry Reference 5-Hydroxy-2-(hydroxymethyl)-4h-pyran-4-one(501-30-4)
IARC 3 (Vol. 79) 2001
EPA Substance Registry System Kojic acid (501-30-4)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Warning
Hazard statements  H351
Precautionary statements  P201-P202-P280-P308+P313-P405-P501a
Hazard Codes  Xn
Risk Statements  40-68
Safety Statements  22-24/25-36/37-36
WGK Germany  3
RTECS  UQ0875000
HS Code  29329995
NFPA 704
1
2 0

Kojic acid price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) K3125 Kojic acid 501-30-4 5G ₹6516.65 2022-06-14 Buy
Sigma-Aldrich(India) K3125 Kojic acid 501-30-4 10G ₹12048.23 2022-06-14 Buy
Sigma-Aldrich(India) K3125 Kojic acid 501-30-4 25G ₹21260.3 2022-06-14 Buy
Sigma-Aldrich(India) 95197 Kojic acid analytical standard 501-30-4 100MG ₹8562.58 2022-06-14 Buy
Sigma-Aldrich(India) 8.18461 5-Hydroxy-2-hydroxymethyl-4H-pyran-4-one for synthesis 501-30-4 10G ₹5620.01 2022-06-14 Buy
Product number Packaging Price Buy
K3125 5G ₹6516.65 Buy
K3125 10G ₹12048.23 Buy
K3125 25G ₹21260.3 Buy
95197 100MG ₹8562.58 Buy
8.18461 10G ₹5620.01 Buy

Kojic acid Chemical Properties,Uses,Production

Chemical Properties

tan powder

Uses

kojic acid is a skin-lightening agent that acts through anti-oxidant activity. Kojic acid is a tyrosinase inhibitor, although it is not as effective as licorice extract. When combined with allantoin and other proper ingredients in sunscreen preparations, the mixture can inhibit uV-caused erythema and accelerate wound healing. It is also found to be skin sensitizing and can be irritating.

Definition

ChEBI: A pyranone that is 4H-pyran substituted by a hydroxy group at position 5, a hydroxymethyl group at position 2 and an oxo group at position 4. It has been isolated from the fungus Aspergillus oryzae.

General Description

Kojic acid, a tyrosinase inhibitor, is produced by several fungi species, including Aspergillus oryzae. It exhibits skin-lightening property, due to its ability to chelate the copper-containing enzyme tyrosinase in the formation of melanin. Kojic acid is also commonly used as a whitening agent in regular cosmetics, bleaching cosmetics, etc. It is found to be a therapeutic agent and helps in preventing pigmentation.

Purification Methods

Crystallise the acid from MeOH (charcoal) by adding Et2O. It sublimes at 150-200o/0.1torr. [Beilstein 18 II 57, 18 III/IV 1145, 18/2 V 516.]

Global( 715)Suppliers
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JSK Chemicals +919879767970 Gujarat, India 3756 58 Inquiry
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Triveni chemicals 08048762458 New Delhi, India 6093 58 Inquiry
Pankaj Chem 08047642937 Delhi, India 14 58 Inquiry

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