Kojic acid
![Kojic acid Structure](CAS/GIF/501-30-4.gif)
- CAS No.
- 501-30-4
- Chemical Name:
- Kojic acid
- Synonyms
- kojic;kojic acid powder;KAD;5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE;4H-Pyran-4-one, 5-hydroxy-2-(hydroxymethyl)-;5-Hydroxy-2-(hydroxyMethyl)-4H-pyranone;KJ ACID;NSC 1942;Kojic acid;Kojci Acid
- CBNumber:
- CB7272507
- Molecular Formula:
- C6H6O4
- Molecular Weight:
- 142.11
- MOL File:
- 501-30-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/1 17:24:36
Melting point | 152-155 °C (lit.) |
---|---|
Boiling point | 179.65°C (rough estimate) |
Density | 1.1712 (rough estimate) |
refractive index | 1.4434 (estimate) |
storage temp. | Store below +30°C. |
solubility | DMSO (Slightly), Methanol (Slightly, Sonicated) |
form | Crystalline Powder |
pka | 7.9(at 25℃) |
color | White to beige-brown |
Water Solubility | SOLUBLE |
λmax | 269nm(CHCl3)(lit.) |
Merck | 14,5317 |
BRN | 120895 |
Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
LogP | -0.640 |
CAS DataBase Reference | 501-30-4(CAS DataBase Reference) |
NIST Chemistry Reference | 5-Hydroxy-2-(hydroxymethyl)-4h-pyran-4-one(501-30-4) |
IARC | 3 (Vol. 79) 2001 |
EPA Substance Registry System | Kojic acid (501-30-4) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS08 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H351 | |||||||||
Precautionary statements | P201-P202-P280-P308+P313-P405-P501a | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 40-68 | |||||||||
Safety Statements | 22-24/25-36/37-36 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | UQ0875000 | |||||||||
HS Code | 29329995 | |||||||||
NFPA 704 |
|
Kojic acid price More Price(16)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | K3125 | Kojic acid | 501-30-4 | 5G | ₹6516.65 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | K3125 | Kojic acid | 501-30-4 | 10G | ₹12048.23 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | K3125 | Kojic acid | 501-30-4 | 25G | ₹21260.3 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 95197 | Kojic acid analytical standard | 501-30-4 | 100MG | ₹8562.58 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 8.18461 | 5-Hydroxy-2-hydroxymethyl-4H-pyran-4-one for synthesis | 501-30-4 | 10G | ₹5620.01 | 2022-06-14 | Buy |
Kojic acid Chemical Properties,Uses,Production
Chemical Properties
tan powder
Uses
kojic acid is a skin-lightening agent that acts through anti-oxidant activity. Kojic acid is a tyrosinase inhibitor, although it is not as effective as licorice extract. When combined with allantoin and other proper ingredients in sunscreen preparations, the mixture can inhibit uV-caused erythema and accelerate wound healing. It is also found to be skin sensitizing and can be irritating.
Definition
ChEBI: A pyranone that is 4H-pyran substituted by a hydroxy group at position 5, a hydroxymethyl group at position 2 and an oxo group at position 4. It has been isolated from the fungus Aspergillus oryzae.
General Description
Kojic acid, a tyrosinase inhibitor, is produced by several fungi species, including Aspergillus oryzae. It exhibits skin-lightening property, due to its ability to chelate the copper-containing enzyme tyrosinase in the formation of melanin. Kojic acid is also commonly used as a whitening agent in regular cosmetics, bleaching cosmetics, etc. It is found to be a therapeutic agent and helps in preventing pigmentation.
Purification Methods
Crystallise the acid from MeOH (charcoal) by adding Et2O. It sublimes at 150-200o/0.1torr. [Beilstein 18 II 57, 18 III/IV 1145, 18/2 V 516.]
Kojic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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chevron_rightSupplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
Vipul Organics Ltd | +91-2266139999 +91-2266139999 | Maharashtra, India | 277 | 58 | Inquiry |
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
Pankaj Chem | 08047642937 | Delhi, India | 14 | 58 | Inquiry |
Supplier | Advantage |
---|---|
JSK Chemicals | 58 |
Vipul Organics Ltd | 58 |
CHEMSWORTH | 30 |
A.J Chemicals | 58 |
CLEARSYNTH LABS LTD. | 58 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
Otto Chemie Pvt. Ltd. | 58 |
Sisco Research Laboratories Pvt. Ltd. | 58 |
Triveni chemicals | 58 |
Pankaj Chem | 58 |
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