TAPS
- CAS No.
- 29915-38-6
- Chemical Name:
- TAPS
- Synonyms
- TAP;3-[TRIS(HYDROXYMETHYL)METHYLAMINO]-1-PROPANESULFONIC ACID;TAPS;TAPS,99%;TAPS,min;TAPS BIOXTRA;TAPS, ULTROL;Taps, puriss;TAPS ULTRAPURE;TAPS SIGMAULTRA
- CBNumber:
- CB2433242
- Molecular Formula:
- C7H17NO6S
- Molecular Weight:
- 243.28
- MOL File:
- 29915-38-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/5 17:10:12
| Melting point | 230-235 °C (dec.) |
|---|---|
| Density | 1.4290 (rough estimate) |
| refractive index | 1.6370 (estimate) |
| Flash point | 110 °C |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | H2O: 1 M at 20 °C, clear, colorless |
| pka | 8.55; pKa (37°): 8.1; pKa2 (25°): 8.28 |
| form | Solid |
| color | White |
| Odor | Odorless |
| PH Range | 7.7 - 9.1 |
| Water Solubility | Soluble |
| Merck | 13,9148 |
| BRN | 2452420 |
| Stability | Stable. Incompatible with strong oxidizing agents |
| InChIKey | YNLCVAQJIKOXER-UHFFFAOYSA-N |
| CAS DataBase Reference | 29915-38-6(CAS DataBase Reference) |
| EPA Substance Registry System | 1-Propanesulfonic acid, 3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]- (29915-38-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 22-24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29221980 | |||||||||
| NFPA 704 |
|
TAPS price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | T9659 | TAPS BioXtra, ≥99.5% (titration) | 29915-38-6 | 100G | ₹15523.05 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T9659 | TAPS BioXtra, ≥99.5% (titration) | 29915-38-6 | 250G | ₹27430.55 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T9659 | TAPS BioXtra, ≥99.5% (titration) | 29915-38-6 | 1KG | ₹81274.1 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T5316 | TAPS BioPerformance Certified, suitable for cell culture, ≥99.5% (titration) | 29915-38-6 | 25G | ₹3637.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T5316 | TAPS BioPerformance Certified, suitable for cell culture, ≥99.5% (titration) | 29915-38-6 | 100G | ₹9926.53 | 2022-06-14 | Buy |
TAPS Chemical Properties,Uses,Production
Description
TAPS is a zwitterionic buffering agent used in biochemistry and molecular biology. It is part of the Tris family of buffers and is useful for a pH range of 7.7 – 9.1. The members of TRIS family are tris(hydroxymethyl)aminomethane (TRIS), N-[tris(hydroxymethyl)methyl]-2-aminoethanesulfonic acid (TES), N-[tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid (TAPS), N-[tris(hydroxymethyl)methyl]-3-amino-2-hydroxypropanesulfonic acid (TAPSO), and N-tris(hydroxymethyl)methyl-4-aminobutanesulfonic acid (TABS) buffers[1]. The solubilities of TAPS in aqueous solution decrease with increasing concentration of the salts (salting-out effect)[2]. TAPS is the preferred culture media buffer used for dinoflagellate experiments, allowing for minimal pH change and maximal growth. It is also often used in capillary electrophoresis to analyze DNA and in planar chromatography to separate dyes. TAPS may form a complex with some common metals so stability constants and concentrations should be taken into account when choosing this buffer. TAPS is capable of inhibiting connexin channels in animal cells.
Chemical Properties
White/clear crystalline powder
Uses
A zwitterionic Good's Buffer
Application
TAPS is a zwitterionic buffer used in biochemistry and molecular biology. It has a useful pH range of 7.7 - 9.1. TAPS has been utilized in capillary electrophoresis of DNA and DNA-dye complexes. Dyes can be separated by planar chromatography with electroosmotic flow containing 1 mM TAPS in the mobile phase. The stability constants of metal ions with TAPS have been investigated through the use of capillary electrophoresis. TAPS has also been shown to inhibit the activity of connexin channels. The activity of various carbonic anhydrases has been studied using TAPS physiological buffer, pKa = 8.4 at 20° C.
References
[1] Gupta B, et al. Stability Constants for the Equilibrium Models of Iron(III) with Several Biological Buffers in Aqueous Solutions. Journal of Solution Chemistry, 2013; 42: 2296–2309.
[2] Taha M, et al. New Insights into Buffer-Ionic Salt Interactions: Solubilities, Transfer Gibbs Energies, and Transfer Molar Volumes of TAPS and TAPSO from Water to Aqueous Electrolyte Solutions. Journal of Solution Chemistry, 2010; 39: 1665–1680.
TAPS Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| LOBA CHEMIE PVT.LTD. | 91-22-6663 6699 | Mumbai, India | 3077 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6160 | 58 | Inquiry |
| Anand Agencies | 91-20-24454597 | Maharashtra, India | 2337 | 58 | Inquiry |
| Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| CHEMSWORTH | 30 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| A.J Chemicals | 58 |
| Otto Chemie Pvt. Ltd. | 58 |
| Alfa Aesar | 58 |
| LOBA CHEMIE PVT.LTD. | 58 |
| Triveni chemicals | 58 |
| Central Drug House(P) Ltd. | 58 |
| Anand Agencies | 58 |
| Sisco Research Laboratories Pvt. Ltd. | 58 |
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