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ChemicalBook > Product Catalog >API >Antibiotics >Cephalosporins Drugs >Ceforanide

Ceforanide

Ceforanide Structure
CAS No.
60925-61-3
Chemical Name:
Ceforanide
Synonyms
C06884;BL-S-786;Ceforanide;CEFORANIDE (200 MG);Antibiotic BL-S-786;Ceforanide USP/EP/BP;Ceforanide (1097807);2-(2,4-Dimethylphenyl)sulf;Bacterial,inhibit,Antibiotic,Inhibitor,Ceforanide;(6R,7R)-7-(2-(2-(Aminomethyl)phenyl)acetamido)-3-(((1-(carboxymethyl)-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CBNumber:
CB2501637
Molecular Formula:
C20H21N7O6S2
Molecular Weight:
519.55
MOL File:
60925-61-3.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:19
Request For Quotation

Ceforanide Properties

Melting point >150° (dec)
Density 1.79±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility Aqueous Base (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
pka 2.52±0.10(Predicted)
form Solid
color White to Pale Brown
Stability Hygroscopic
InChIKey SLAYUXIURFNXPG-CRAIPNDOSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H317-H334
Precautionary statements  P261-P280-P284-P304+P340-P342+P311
HS Code  2941906000

Ceforanide Chemical Properties,Uses,Production

Description

Ceforanide is a second generation cephalosporin with good β-lactamase resistance. It has a serum half-life of about three hours, allowing twice-daily dosing.

Uses

Ceforanide is a cephalosporin based antibiotic used in the sterilization in various medical procedures.

Definition

ChEBI: A second-generation cephalosporin antibiotic with {[1-(carboxymethyl)-1H-tetrazol-5-yl]sulfanyl}methyl and 2-(aminomethyl)phenylacetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is effective against many col forms, including Escherichia coli, Klebsiella, Enterobacter and Proteus, and most strains of Salmonella, Shigella, Hemophilus, Citrobacter and Ari ona species.

Antimicrobial activity

A semisynthetic parenteral cephalosporin with activity broadly similar to that of cefalotin. Its activity in vitro is significantly reduced in the presence of serum. A 1 g intravenous dose achieves a concentration of c. 135 mg/L at the end of infusion. The response after 0.25, 0.5 and 1 g intravenous doses is essentially linear. A 1 g intramuscular dose produces mean peak values of around 70 mg/L. Plasma protein binding is around 85%.
It is almost entirely eliminated in the urine with a halflife of about 2.5 h, 80–95% being recovered in the first 12 h. The half-life is inversely related to renal function, rising to around 20 h when the creatinine clearance falls below 5 mL/min. About half the dose is removed by hemodialysis over 6 h.
It is generally well tolerated; phlebitis and pain at the site of injection are reported in some patients with occasional transient neutropenia and increased transaminase levels. It has been used principally for the treatment of infections due to Gram-positive cocci, including staphylococcal and streptococcal soft-tissue infections, but is no longer widely available.

Ceforanide Preparation Products And Raw materials

Raw materials

Preparation Products

Ceforanide Suppliers

Global( 86)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29888 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49392 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. +86-0551-65418671 +8618949823763 China 34571 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-029-89586680 +86-18192503167 China 8444 58 Inquiry
Finetech Industry Limited +86-27-87465837 +8618971612321 China 9640 58 Inquiry
Supplier Advantage
A.J Chemicals 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Pharma Affiliates 58
CLEARSYNTH LABS LTD. 58
career henan chemical co 58
Chongqing Chemdad Co., Ltd 58
CONIER CHEM AND PHARMA LIMITED 58
Hefei TNJ Chemical Industry Co.,Ltd. 58
Shaanxi Dideu Medichem Co. Ltd 58
Finetech Industry Limited 58

60925-61-3(Ceforanide)Related Search:

Acetyl chloride PHENYL VALERATE Acetaminophen Acetylacetone Acetyl coenzyme A sodium salt
2-aminomethylphenylacetic acid (intermediate of ceforanide) 2-(5-Mercaptotetrazole-1-yl)ethanol 1H-Tetrazole-1-acetic acid 7-TMCA 7-Phenyl-acetamido-deacetoxy-cephalosporanic-acid
1-Ethyl-1H-1,2,3,4-tetrazole-5-thiol Phenylacetic acid 5-Mercapto-1H-tetrazole-1-acetic acid 1-ETHYL-1H-TETRAZOLE Ceforanide
Acetyl-resveratrol ACETAMINOPHENOL BP/USP 1H-Tetrazole, 5-((3-(ethylthio)propyl)thio)-1-methyl-
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CEFORANIDE (200 MG) Ceforanide (6R,7R)-7α-[[(2-Aminomethylphenyl)acetyl]amino]-3-[[[1-(carboxymethyl)-1H-tetrazol-5-yl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Antibiotic BL-S-786 BL-S-786 C06884 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[2-[2-(aMinoMethyl)phenyl]acetyl]aMino]-3-[[[1-(carboxyMethyl)-1H-tetrazol-5-yl]thio]Methyl]-8-oxo-,(6R,7R)- (6R,7R)-7-[[2-[2-(Aminomethyl)phenyl]acetyl]amino]-3-[[1-(carboxymethyl)tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 2-(2,4-Dimethylphenyl)sulf Ceforanide USP/EP/BP (6R,7R)-7-(2-(2-(Aminomethyl)phenyl)acetamido)-3-(((1-(carboxymethyl)-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Ceforanide (1097807) Bacterial,inhibit,Antibiotic,Inhibitor,Ceforanide 60925-61-3 C20H21N7O6S2 Ceforanide