4-(4-Fluorophenyl)-3-hydroxymethyl-1-methyl-piperidine

4-(4-Fluorophenyl)-3-hydroxymethyl-1-methyl-piperidine Structure
CAS No.
109887-53-8
Chemical Name:
4-(4-Fluorophenyl)-3-hydroxymethyl-1-methyl-piperidine
Synonyms
forParoxetine;trans-4-(4-FL;UNII:QRA30YT0AV;rac-trans Paroxol;)-3-hydroxymethyL;(+/-)-TRANS PAROXOL;(+/-)-Trans-paroxol;Paroxetine Impurity 8;trans-4-(p-Fluorophenyl)-1-Me;(-)Trans-4-(4-Fluorophenyl)-3-
CBNumber:
CB2737005
Molecular Formula:
C13H18FNO
Molecular Weight:
223.29
MOL File:
109887-53-8.mol
MSDS File:
SDS
Modify Date:
2024/3/28 13:39:29

4-(4-Fluorophenyl)-3-hydroxymethyl-1-methyl-piperidine Properties

Melting point 119-121°C
Boiling point 300.3±42.0 °C(Predicted)
Density 1.092±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
form Solid
pka 14.93±0.10(Predicted)
color White to Pale Yellow
CAS DataBase Reference 109887-53-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xn,N
Risk Statements  22-41-51/53
Safety Statements  22-26-39-61

4-(4-Fluorophenyl)-3-hydroxymethyl-1-methyl-piperidine Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Racemic Paroxetine intermediate.

4-(4-Fluorophenyl)-3-hydroxymethyl-1-methyl-piperidine Preparation Products And Raw materials

Raw materials

Preparation Products

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(-)Trans-4-(4-Fluorophenyl)-3- TRANS-4-(4-FLUOROPHENYL)-3-HYDROXY METHYL-N-METHYL PIPERIDINE (3R,4S)-4-(4-FLUOROPHENYL)-1-METHYL-3-PIPERIDINE METHANOL (+/-)-TRANS PAROXOL (+/-)-TRANS-4R-(4-FLUOROPHENYL)-3S-HYDROXYMETHY-1-METHYLPIPERIDINE Trans-4-(p-Fluorophenyl)-3-pydroxymethyl-1-methylpiperidine ((3R)-4-(4-fluorophenyl)-1-methylpiperidin-3-yl)methanol 3R,4S-4-[(4-fluorophenyl)-1-methylpiperi dinyl] methanol rac-trans Paroxol [4-(2-fluorophenyl)-3-Methoxypiperidin-1-yl]Methylidyne trans-3-HydroxyMethyl-4-(4-fluorophenyl)-N-Methylpiperidine trans-4-(p-Fluorophenyl)-1-Me 3-PiperidineMethanol,4-(4-fluorophenyl)-1-Methyl-, (3R,4S)-rel- TRANS-4-(P-FLUOROPHENYL)-3-HYDROXYMETHYL-1-METHYLPIPERIDINE (+/-)-TRANS-4-(FLUOROPHENYL)-3-HYDROXYMETHYL-1-METHYLPIPERIDINE (+/-)-TRANS-4-(4-FLUOROPHENYL)-3-HYDROXYMETHYL-1-METHYLPIPERIDINE TRANS(+/-)-4-(4-FLUOROPHENYL)-3-HYDROXYMETHYL-1-METHYLPIPERIDINE TRANS-4-(4-FLUOROPHENYL)-3-HYDROXYMETHYL-1-METHYLPIPERIDINE Trans-4-(4-fluorophenyl)-3-hydroxymethyl-1-methylpiper-dine trans-N-Methyl-4-(4-fluorophenyl)-3-(hydroxyMethyl)piperidine ((3R,4S)-rel-4-(4-Fluorophenyl)-1-Methylpiperidin-3-yl)Methanol (3R-,4S)-REL-4-(4-FLUOROPHENYL)-1-METHYL-3-PIPERIDINE METHANOL 4-(4-fluorophenyl)-3-hydroxymethyl-1-methyl-piperidine trans-4-(4-Fuorophenyl)-3-hydroxymethyl-1-methylpiperidine Trans-4-(4-Fluorophenyl)-3-Hydroxylmethylpiperidine forParoxetine (3S,4R)-3-(((6-chlorobenzo[d][1,3]dioxol-5-yl)oxy)methyl)-4-(4-fluorophenyl)piperidine Paroxetine Impurity 8 (4-(4-Fluorophenyl)-3-hydroxymethyl-1 Paroxetine Impurity 8 trans-4-(4-FL Paroxetine Impurity 8 (4-(4-Fluorophenyl)-3-hydroxymethyl-1-methyl-piperidine) )-3-hydroxymethyL ((3R,4S)-4-(4-fluorophenyl)-1-methylpiperidin-3-yl)methanol compound with ((3S,4R)-4-(4-fluorophenyl)-1-methylpiperidin-3-yl)methanol (1:1) (-)trans-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine (+/-)-Trans-paroxol rel-(3R,4S)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol trans-4-(4-fluorophenyl)-1-methyl-3-piperidyl]methanol (+/-)-Trans-[4-(4-Fluoro-phenyl)-1-methyl-piperidin-3-yl]-methanol rel-((3S,4R)-4-(4-Fluorophenyl)-1-methylpiperidin-3-yl)methanol UNII:QRA30YT0AV 109887-53-8 C13H18FNO Aromatics Heterocycles Inhibitors Intermediates & Fine Chemicals Pharmaceuticals