Eberconazole
- CAS No.
- 128326-82-9
- Chemical Name:
- Eberconazole
- Synonyms
- Eberconazole;1H-Imidazole, 1-(2,4-dichloro-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-;(+/-)-1-(2,4-Dichloro-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)imidazole
- CBNumber:
- CB31178592
- Molecular Formula:
- C18H14Cl2N2
- Molecular Weight:
- 329.22
- MOL File:
- 128326-82-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/4 17:34:32
Eberconazole Chemical Properties,Uses,Production
Description
Eberconazole is a new member of the azole class of antifungal agents, and it is indicated for the topical treatment of cutaneous fungal infections, including tinea corporis (ringworm of the body), tinea cruris (ringworm of the groin) and tinea pedis (athlete’s foot) infections. Its mode of action is similar to that of other azole antifungals, namely inhibition of fungal lanosterol 14α-demethylase. Eberconazole exhibits good in vitro activity against a wide range of Candida species, including Candida. tropicalis, dermatophytes and Malassezia spp. yeasts. It shows good activity against Candida. Parapsilosis (MIC90=0.125 mg/mL), which is a relevant species in skin and nail disorders. In addition, eberconazole is effective against some of the highly triazole-resistant yeasts such as Candida. glabrata and Candida. krusei, as well as fluconazole-resistant Candida. albicans. However, eberconazole is less active than clotrimazole and ketoconazole against Candida. neoformans and a number of clinically relevant molds. Eberconazole is supplied as a 1% or 2% cream, and the topical application does not result in detectable serum, urine, or fecal levels. In a phase II study of 60 patients with tinea corporis and tinea cruris, treatment with topical eberconazole (1% or 2% cream), applied once or twice daily for 6 weeks, resulted in cure rates ranging from 73.3–93.3% at the end of therapy, and 66.7–100% six weeks post-therapy.
Uses
Eberconazole can be used for a novel antifungal formulation.
Eberconazole Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| BDR Pharmaceuticals International Pvt Ltd | +91-2240560560 +91-7718884418 | Maharashtra, India | 206 | 58 | Inquiry |
| Bioaltus Laboratories Pvt Ltd | +91-2249744539 +91-9820139885 | Maharashtra, India | 34 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Santo Righello Private Limited | 08068970644Ext 147 | Hyderabad, India | 29 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| TargetMol Chemicals Inc. | 15002134094 | China | 28091 | 58 | Inquiry |
| QUALITY CONTROL SOLUTIONS LTD. | 13670046396 | China | 18865 | 58 | Inquiry |
| Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd | 18162595016; 18162595016 | China | 9102 | 58 | Inquiry |
| Lanospharma Laboratories Co.,Ltd | 13440048448 | China | 6343 | 56 | Inquiry |
| Nanjing Rhine Pharm Tech Inc. | 025-85438061 15850564305 | China | 7 | 34 | Inquiry |
128326-82-9(Eberconazole)Related Search:
1of4
chevron_right