Pramlintide

Pramlintide Structure
CAS No.
151126-32-8
Chemical Name:
Pramlintide
Synonyms
CL062;Pramlintide;Triproamylin;Pramlintide D10;Lys-c[Cys-Asn-Thr-Ala-Thr-Cys]-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu -Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Pro-Ile-Leu-Pro-Pro-Thr-Asn-Val-Gly -Ser-Asn-Thr-Tyr-NH2;PramlintideQ: What is Pramlintide Q: What is the CAS Number of Pramlintide Q: What is the storage condition of Pramlintide Q: What are the applications of Pramlintide
CBNumber:
CB31179559
Molecular Formula:
C171H267N51O53S2.C2H4O2.H2O
Molecular Weight:
4027.49
MOL File:
151126-32-8.mol
Modify Date:
2024/4/16 14:59:45

Pramlintide Properties

solubility soluble in Water
form Solid
color White
Water Solubility Soluble to 1 mg/ml in water

Pramlintide Chemical Properties,Uses,Production

Uses

Antidiabetic.

Enzyme inhibitor

This 37-residue pancreatic β-cell hormone (MW = 3.9 kDa; Sequence: KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY), also called Islet Amyloid Polypeptide (IAPP), is co-secreted with insulin and plays a role in glycemic regulation by retarding gastric emptying and promoting satiety. Amylin helps to prevent post-prandial spikes in blood glucose. Amylin potently inhibits (EC50 = 18 pM) amino acid-stimulated glucagon secretion. (Note: Human amylin is amyloidogenic, whereas the synthetic hormone known as Pramlintide (MW = 3951.41g; CAS 151126-32-8; Sequence: KCNTATCATQRLANFLVHSSNNFGPILPPTNVGSNTY-NH2; Tradename: Symlin?) contains three prolyl residues that are found in Rat Amylin (Sequence: KCNTATCATQRLANFLVRSSNNLGPVLPPTNG SNTY) and is nonamyloidogenic.)

Pramlintide Preparation Products And Raw materials

Raw materials

Preparation Products

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Triproamylin Lys-c[Cys-Asn-Thr-Ala-Thr-Cys]-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu -Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Pro-Ile-Leu-Pro-Pro-Thr-Asn-Val-Gly -Ser-Asn-Thr-Tyr-NH2 CL062 Pramlintide D10 PramlintideQ: What is Pramlintide Q: What is the CAS Number of Pramlintide Q: What is the storage condition of Pramlintide Q: What are the applications of Pramlintide Pramlintide 151126-32-8