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Sermorelin acetate

Sermorelin acetate Structure
CAS No.
114466-38-5
Chemical Name:
Sermorelin acetate
Synonyms
SERMORELIN ACETATE;sermoreli;GHRH (1-29);DSIP powder;Sermorelin acetate [USAN];Sermorelin acetate hydrate;Sermorelin Acetate(acetate)
CBNumber:
CB31473150
Molecular Formula:
C149H246N44O42S
Molecular Weight:
3357.91
MOL File:
114466-38-5.mol
Modify Date:
2024/7/25 20:04:51

Sermorelin acetate Properties

storage temp. 0 - 4 °C for short term, or -20 °C for long term
solubility Soluble in DMSO, not in water
InChIKey WGWPRVFKDLAUQJ-PUMMXPSGNA-N

Sermorelin acetate Chemical Properties,Uses,Production

Description

Sermorelin acetate, also known as INN/Geref/Gerel, is a peptide analogue of growth hormone-releasing hormone (GHRH) used as a diagnostic agent to evaluate growth hormone (GH) secretion and diagnose growth hormone deficiency. It is a 29 amino acid polypeptide representing fragments 1-29 from endogenous human GHRH and is considered to be the shortest fully functional fragment of GHRH.

Uses

Sermorelin acetate is used as a diagnostic agent to assess growth hormone (GH) secretion. It is also used as doping agent in sports due to its correlation with increased growth of muscular and skeletal tissue. Sermorelin use is also hypothesized to improve deep rapid eye movement sleep.

benefits

The benefits of using Sermorelin acetate therapy are multifaceted and include: helping to increase muscle strength, weight loss, improved bone mineral density, improved cognitive health, increased energy levels, restoration of sexual dysfunction, improvement of cardiovascular disease, enhancement of the immune system, improvement of skin health, and a boost in metabolism.

Side effects

All medicines may cause side effects, but many have no or minor side effects. The most common side effects: Facial flushing; headache; nausea; pain, redness, or swelling at the injection site; paleness; strange taste in mouth; vomiting.
The Severe side effects : Severe allergic reactions (rash, hives, itching, difficulty breathing, tightness in the chest, swelling of the mouth, face, lips, or tongue).

References

Influence of growth hormone (GH) and GH-releasing factor on locomotor activity in rats DOI: 10.1016/0196-9781(93)90101-L
Comparison of GH-stimulation by GH-RH(1-29)NH2 and an agmatine29 GH-RH analog, after intravenous, subcutaneous and intranasal administration and after pulmonary inhalation in rats DOI: 10.1111/j.1399-3011.1993.tb00332.x
Potent agonists of growth hormone-releasing hormone Part I DOI: 10.1111/j.1399-3011.1992.tb00791.x
Synthesis and in vitro and in vivo activity of analogs of growth hormone-releasing hormone (GH-RH) with C-terminal agmatine DOI: 10.1111/j.1399-3011.1990.tb00988.x
Growth-hormone-releasing hormone DOI: 10.1093/clinchem/36.3.415

Sermorelin acetate Preparation Products And Raw materials

Raw materials

Preparation Products

Sermorelin acetate [USAN] Sermorelin Acetate(acetate) Sermorelin acetate hydrate GHRH (1-29) sermoreli SERMORELIN ACETATE DSIP powder 114466-38-5 C149H246N44O42 C149H246N44O42SC2H4O2