2-Ethyl-2-phenylmalonamide

2-Ethyl-2-phenylmalonamide Structure
CAS No.
7206-76-0
Chemical Name:
2-Ethyl-2-phenylmalonamide
Synonyms
PEMA;pema(amide);Primidone Impurity A;Phenylethylmalonamide;Primidone, M(diamide);Ethylphenylmalonamide;Ethylphenylmalondiamide;Phenylethylmalondiamide;Primidone EP Impurity A;Phenobarbital Impurity 5
CBNumber:
CB3122121
Molecular Formula:
C11H14N2O2
Molecular Weight:
206.24
MOL File:
7206-76-0.mol
MSDS File:
SDS
Modify Date:
2023/5/15 10:44:01

2-Ethyl-2-phenylmalonamide Properties

Melting point 120°C
Boiling point 440.9±45.0 °C(Predicted)
Density 1.183±0.06 g/cm3(Predicted)
Flash point 113 °C
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 14.98±0.50(Predicted)
color White to Off-White
Water Solubility <0.01 g/100 mL at 18 ºC
Stability Stable. Combustible. Incompatible with strong oxidizing agents.
NIST Chemistry Reference Propanediamide, 2-ethyl-2-phenyl-(7206-76-0)
EPA Substance Registry System 2-Phenyl-2-ethylmalonamide (7206-76-0)

SAFETY

Risk and Safety Statements

HS Code  2924296000
NFPA 704
1
1 0

2-Ethyl-2-phenylmalonamide price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) PHR3110 Primidone Related Compound A pharmaceutical secondary standard, certified reference material 7206-76-0 50MG ₹61605.08 2022-06-14 Buy
Product number Packaging Price Buy
PHR3110 50MG ₹61605.08 Buy

2-Ethyl-2-phenylmalonamide Chemical Properties,Uses,Production

Chemical Properties

White Crystalline Solid

Uses

A metabolite of Primidone

General Description

White crystalline solid.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2-Ethyl-2-phenylmalonamide is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Health Hazard

SYMPTOMS: Symptoms of exposure to a related compound through ingestion may include sedation, vertigo, dizziness, nausea, vomiting, ataxia, diplopia, nystagmus, an acute feeling of intoxication and, rarely, maculopapular and morbilliform rash, leukopenia, thrombocytopenia, systemic lupus erythematosus, lymphadenopathy, acute psychotic reactions, hemorrhagic disease in the neonate, megaloblastic anemia and osteomalacia.

Fire Hazard

Flash point data for 2-Ethyl-2-phenylmalonamide are not available. 2-Ethyl-2-phenylmalonamide is probably combustible.

2-Ethyl-2-phenylmalonamide Preparation Products And Raw materials

Raw materials

Preparation Products

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ETHYLPHENYLMALONIC ACID DIAMINE 2-ETHYL-2-PHENYLMALONAMIDE PEMA 2-ethyl-2-phenyl-malonamid 2-Ethyl-2-phenylmalondiamide 2-Ethyl-2-phenylmalonic diamide 2-ethyl-2-phenyl-propanediamid 2-ethyl-2-phenylpropanediamide Ethylphenylmalondiamide Malonamide, 2-ethyl-2-phenyl- pema(amide) Phenylethylmalonamide Phenylethylmalondiamide Primidone, M(diamide) Propanediamide, 2-ethyl-2-phenyl- PriMidone Related CoMpound A Phenobarbital Impurity 5 Primidone Impurity 1(Primidone EP Impurity A) Primidone EP Impurity A Phenobarbital Impurity 1 Ethylphenylmalonamide Primidone Related Compound A (2-ethyl-2-phenylmalonamide) (1562011) 2-ethyl-2-phenylpropanediamide(ethylphenylmalonamide) Primidone Impurity A 7206-76-0 Chemical Amines Amines Aromatics Metabolites & Impurities Intermediates & Fine Chemicals Pharmaceuticals